Bipolar Disorder Drugs (Week 6) Flashcards
what kind of drug is valproate?
Teratogenic
for what kind of symptoms does valproate work best for?
Better for mixed episodes than lithium
what are the side effects of carbamazepine?
leucopenia/agranulocytosis
what are some important things to know about oxcarbazepine?
Better safety index; no GI
issues, no alterations in liver
enzymes (fewer drug
interactions), no leucopenia
(no monitoring required)
what are some important things to know gabapentin/pregabalin?
Excellent safety profile; not metabolized by liver, excreted intact
what are some important things to know
topiramate?
Not super useful as a txt for BD, per se,
however induces weight loss, which can
counteract weight gain seen with other BD
drugs
One of the most serious side effects associated with taking Lamictal is
rash
The therapeutic index for lithium is __________; the antidote for overdose is ______________
low; unavailable
Topamax is used in the treatment of Bipolar Disorder to decrease
weight gain
Antiepileptics include all of the following drugs except
lithium
Valproate appears to be more effective for patients who have ________________, compared to lithium.
mixed episodes.
What is the original primary indication for lamotrigine?
seizure disorder/epilepsy
Electro-convulsive therapy (ECT) is sometimes used to treat Bipolar Disorder because
it has rapid effects
Bipolar patients spend most of their lives in a ____________ state.
asymptomatic
The rate of suicide for bipolar patients is approximately _____ times that of the general population.
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