BIORISK MANAGMENT Flashcards
Risk associated with biological toxins like venom or infectious agents.
Biorisk
6 Risks
Unintentional Exposure
Accidental Release
Theft
Misuse
Diversion
Intentional Release
According to the CEN Workshop Agreement (CWA) 15793:2011, BRM is “a system or process to control safety and security risks associated with the handling or storage and disposal of biological agents and toxins in laboratories and facilities.”
Biorisk Management
Three primary components Biorisk Mangament
assessment (A)
mitigation (M)
performance (P)
This risk response is preventive measures
Mitigation
This risk response is about - safety measures and planning.
Avoidance
This risk response is about information and “ihasa”
Transference
This risk response is the last resort
Acceptance
Like a three-legged stool, a biorisk management system fails if one of the components, or legs, is overlooked or is not addressed.
AMP model
In contrast to other risk management models, which typically focus heavily on mitigation measures, AMP focuses on all components with?
equal attention
In order for a risk to occur, there must be a situation for the hazard to cause harm.
Risk Assessment
Hazard = Object
_______ = Probability
Risk
identify the hazards and risks of the biological agents to be handled.
Define situation
review of how individuals inside and outside the laboratory may be exposed to the hazards.
Define the risk
overall biosafety risks, the risk assessment team needs to compare the likelihood; either qualitatively or quantitatively,.
Characterize the risks
take into account the adequacy of any existing controls and decide whether or not the biorisk is acceptable.
Determine if risks are acceptable or not
- Second fundamental component
- Action and control measures
- Reduce or eliminate the risks
- The five major areas of control or measures.
Mitigation Procedures
involves the total decision not to work with a specific biological agent or even not doing the intent work.
Elimination
replacement of the procedures or biological agent with a similar entity in order to reduce the risk.
Substitution
physical changes in work stations, equipment, production facilities, or any other relevant aspect of the work environment that can reduce or prevent exposure to hazards.
Engineering Controls
policies, standards, and guidelines used to control risks. Proficiency and competency training for laboratory staff.
Administrative Controls
These are devices worn by workers to protect them against chemicals, toxins, and pathogenic hazards in the laboratory.
Personal Protective Equipment (PPE)
- The last pillar of the biorisk management model.
- A systematic process intended to achieve organizational objectives and goals.
- Performance management is simply a reevaluation of the overall mitigation strategy.
Performance Evaluation
Steps of Performance Evaluation
- Identify the Key issues of concern
- Define Outcomes indicators and metrics
- Define Activities indicators and metrics
- Collect Data and Report indicator result
- Act on finding from performance indicators
- Evaluate and Refine performance indicators
