Biology Flashcards

1
Q

Under origin of life,what two approaches help us understand this concept?
Define them each
State and define the types of generations under Philosophy

Origin of life remains a scientific problem which is not yet solved
􏰀 It is generally agreed that all life today evolved by common descent from a single primitive life form.
􏰀 It is not known how this early form came about, but scientists think it was a natural process which took place perhaps 3,900 million years ago.
True or false

A

Religion:
􏰀Origin and meaning of life? 􏰀 Two approaches:
1. Religion:
􏰀 Set of dogmas, usually based on revelation – faith
􏰀 Incontrovertible truth
􏰀 E.g. Belief in the supernatural; trust in biblical teachings)
􏰀 Generally in the form of creation myths – narrative of how the world began and living things inhabit it
􏰀 Are considered sacred accounts and can be found in nearly all known religious traditions
􏰀 Are all stories with a plot and characters who are either deities, human-like figures, or animals, who often speak and transform
easily

Philosophy or science :

Confronting the mysteries of the world with questions,
doubts, curiosity, explanatory endeavours
􏰀 search for natural explanations from observable forces of
nature
􏰀 Spontaneous generation
􏰀 formation of living organisms from inanimate matter 􏰀 fleas could arise from dust,
􏰀 maggots could arise from dead flesh
􏰀 Mice could arise from a pile of rubbish
􏰀 Equivocal generation
􏰀 species arise from unrelated organisms
• Ticks arise from dogs

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2
Q

What is the main hypothesis that supports genetics first and which supports metabolism
Define the hypothesis for both
What did Rudolf Virchow propose in biology? And in which year did he propose what he proposed?

A

It is not known whether metabolism or genetics came first.
􏰀 The main hypothesis which supports genetics first is the RNA
World Hypothesis,
􏰀 self-replicating RNA molecules proliferated before the evolution of DNA and proteins.
􏰀 The main hypothesis which supports metabolism first is the Protein Interaction World hypothesis.
􏰀 The’protein interaction world hypothesis of the origins of life assumes that life emerged as a self-reproducing and expanding system of protein interactions.
􏰀 Rudolf Virchow: Biologist who proposed that all living things are composed of cells, and that all cells arise from pre-existing cells (1858)

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3
Q
Difference between science and religion 
When were cells first discovered?
Who said all plants are made of cells?
Who said animals are made up of cells?
What is a cell?
What are the two types of cellular organisms and state an example each
A

Religion: Set of often revealed dogmas in which there is no alternative or much leeway in interpretation
􏰀Science: Places premium on alternative explanations and readiness to replace one theory with another

Cells were first discovered after examining a thin slice of cock – Robert Hook- 1665. He also contributed to microscopes and did hookes law
􏰀 Only dead cell walls of plants were observed
􏰀 All plants are made up of cells – Mathias J. Schleiden
􏰀 Extended to animals — Theodore Schwann
􏰀 Cell - basic building block of organisms
􏰀 Cells can further be broken down to constituent parts.
􏰀 Constituents parts cannot live and function independently as a living matter.
􏰀 Unicellular organisms
􏰀 bacteria, paramecium and amoeba
􏰀 Multicellular organisms

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4
Q

What are the types of cells? Define them a ns give two examples each

What are the macromolecule components of the plasma membrane?
What about the nucleus?
Which structure in the cell is known as “little organs”?
Which structure in the cell is used for protein synthesis?
Which is used for processing and packaging proteins and lipids?
Which is derived from golgi bodies?
Which structure in green plant cell is used for photosynthesis?
Which structure in a mature green plant cell stores nutrients and toxic waste?
What is the cell wall made up of in plants? What about in fungus?
Between flagella and cilia, which has shorter hair like structures for locomotion?
Which extends from the cell?

A

􏰀 Eukaryotic – has nucleus and is bounded by a pair of nuclear envelope
􏰀 protists, fungi, plants, animals
􏰀 Prokaryotic cell has no definite nucleus 􏰀 No membrane bound organelle
􏰀 Nucleoid diffused
􏰀 bacteria
􏰀 Akaryotic cells have no nucleus but are merely genetic
information surrounded by a protein coat
􏰀 include viruses and are sometimes not considered as cells but particles

Cells possess the following basic features:
􏰀 Cytoplasm: Gel-like substance which is the cell itself
􏰀 Plasma (Cell) Membrane: Outermost cell surface (proteins, lipids)
􏰀 Nucleus: Composed primarily of protein and DNA organized into chromosome units (with genes) and enclosed in a membrane
􏰀 Organelles: A number of microscopic bodies found in cytoplasm; the name means ‘little organs’
􏰀 Endoplasmic Reticulum (ER): Series of membranes running through cytoplasm, some are studded with ribosomes (rough ER) for protein synthesis
􏰀 Golgi Body (Apparatus): System of sacs for processing and packaging proteins and lipids
GEMP Tutorial 9

CELL STRUCTURE (2) 􏰀 Lysosome: Derived from Golgi bodies, with enzymes for digestion in the cell 􏰀 Mitochondria: Releases quantities of energy to form ATP; ‘powerhouse’ of the cell 􏰀 Chloroplast: Found in green plant cells for photosynthesis 􏰀 Vacuole: Large, fluid-filled organelle in mature plant cells; stores nutrients and toxic wastes 􏰀 Cell Wall: Found outside plasma membrane in plant (cellulose), fungal (chitin) and bacterial cells; provide support from mechanical pressures 􏰀 Flagella: Long, hair-like organelles extending from the cell, for locomotion 􏰀 Cilia: Shorter hair-like structures for locomotion
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5
Q

State ten differences between animal cells and plant cells

A

Plant cells have a fixed rectangular shape while animal cells have irregular shape or round shape .
Animal cells have lysosomes but plant cells use their vacuoles for degradation of cellular waste and toxins .
Plant cells have photosynthesis occurring in the mitochondria
Animal cells have smaller and more numerous vacuoles as compared to plant cells vacuoles. Plant cell vacuoles are way bigger. The vacuoles in animal cells are called vesicles. Some vesicles are organelles example, lysosomes,Golgi apparatuses,endosomes,Peroxisomes.
Animal cell membranes give them flexibility since they don’t have cell wall.
Animal cells have centrioles but plant cells don’t
Plant cells have chloroplasts,cell wall, tonoplasts,plasmalemma,glycoxysome and cell wall.
Apart from these, plant cells have everything that animal cells have

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6
Q

A cell has lysosome, mitochondria, Golgi body, smooth
and rough ER. Based on this information, the cell could not be
A. A tapeworm cell
B. A yam cell
C. Yeast cell
D. Escherichia coli cell
E. Plasmodium falciparum cell

You would expect a cell with an extensive Golgi apparatus to
a. make a lot of ATP.
b. secrete a lot of material.
c. move actively.
d. perform photosynthesis.
e. store large quantities of food
􏰀 Which of the following statements is not correct?
A. A eukaryotic cell contains nucleus that is bounded by nuclear
envelope.
B. A prokaryotic cell has no definite nucleus
C. An akaryotic cells has no nucleus but is merely genetic information surrounded by a protein coat
D. The diffused nuclear material of the eukoryotic cell is the nucleoid.
E. In eukaryotic cells, RNA-synthesis takes place inside the nucleus
whilst protein synthesis occurs in the in cytoplasm.

Find the answers

A
  1. Is D. The cell described with lysosomes, mitochondria, Golgi body, smooth and rough endoplasmic reticulum (ER) is characteristic of eukaryotic cells. Among the options provided:
    Jhhhhh
  • A. A tapeworm cell: Tapeworms are multicellular eukaryotic organisms, so they have cells with organelles like lysosomes, mitochondria, Golgi bodies, and ER.
  • B. A yam cell: Yam cells are also eukaryotic and possess these organelles.
  • C. Yeast cell: Yeast cells are single-celled eukaryotic organisms that have all these organelles.
  • D. Escherichia coli cell: Escherichia coli is a prokaryotic bacterium, which lacks membrane-bound organelles like mitochondria, Golgi bodies, and lysosomes.
  • E. Plasmodium falciparum cell: Plasmodium falciparum is a unicellular eukaryotic parasite, and its cells contain organelles such as mitochondria and ER, but may lack some other organelles depending on the stage of its lifecycle.

Therefore, the correct answer based on the presence of lysosomes, mitochondria, Golgi body, smooth and rough ER would be:

D. Escherichia coli cell

Escherichia coli is a prokaryotic cell and does not have membrane-bound organelles like lysosomes, mitochondria, Golgi bodies, smooth ER, or rough ER.

2.Is B
3.D.

Let’s address each question and statement:

  1. Question: You would expect a cell with an extensive Golgi apparatus to
    • Answer: b. secrete a lot of material.
      • The Golgi apparatus in cells is responsible for modifying, sorting, and packaging proteins and lipids into vesicles for secretion to other parts of the cell or outside the cell. Therefore, a cell with an extensive Golgi apparatus would likely be involved in secreting a lot of material.
  2. Statement: Which of the following statements is not correct?
    • Answer: D. The diffused nuclear material of the eukoryotic cell is the nucleoid.
      • This statement is incorrect because “nucleoid” is a term used in prokaryotic cells to refer to the region where genetic material (DNA) is located, but it is not surrounded by a membrane-bound nucleus. In contrast, eukaryotic cells have a well-defined nucleus bounded by a nuclear envelope where genetic material is contained within chromosomes.
      Let’s review the other statements for clarity:
      - A. A eukaryotic cell contains nucleus that is bounded by nuclear envelope.
      - This statement is correct. Eukaryotic cells have a nucleus that is surrounded by a double membrane called the nuclear envelope.
      • B. A prokaryotic cell has no definite nucleus
        • This statement is correct. Prokaryotic cells lack a membrane-bound nucleus; instead, their genetic material is located in a region called the nucleoid.
      • C. An akaryotic cells has no nucleus but is merely genetic information surrounded by a protein coat
        • This statement describes a virus, not a cellular organism. Viruses are acellular and consist of genetic material (DNA or RNA) surrounded by a protein coat (capsid).
      • E. In eukaryotic cells, RNA-synthesis takes place inside the nucleus whilst protein synthesis occurs in the cytoplasm.
        • This statement is correct. In eukaryotic cells, RNA synthesis (transcription) occurs inside the nucleus, where DNA is transcribed into RNA. The RNA then exits the nucleus and travels to the cytoplasm, where protein synthesis (translation) occurs on ribosomes.the rna in eukaryotes nu, remember we have mrna rrna trna

Therefore, the incorrect statement among the options provided is:

D. The diffused nuclear material of the eukoryotic cell is the nucleoid.

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7
Q
What is a tissue
Give two examples each of plant and animal tissues 
What is an organ
What is an organ system
Give two examples of each
A
A tissue is a group of cells that are similar in structure and are bounded by intracellular material to perform a common function.
􏰀 Plants
􏰀 epidermis
􏰀 periderm tissues 􏰀 vascular tissue
􏰀 xylem tissues, phloem tissue 􏰀 parenchyma tissue,
􏰀 sclerenchyma tissue
􏰀 collenchyma
􏰀 Animals
􏰀 Epithelia tissues
􏰀 connective tissues (e.g. blood tissue, cartilage tissue, bone tissue) 
􏰀 nerve tissue
􏰀 muscle tissue

Organ
􏰀 A group of different tissues that perform a common
function are called an organ. 􏰀 The skin of an animal
􏰀 Tissues :
􏰀 epithelium, 􏰀 muscle,
􏰀 nerve,
􏰀 hair,
􏰀 blood.
􏰀 Organ systems
􏰀 a group of organs that interact to perform a common function
which contributes to the survival of the body.
􏰀 Digestion system : teeth, stomach, pancreas, intestines etc.

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8
Q

What are carbohydrates
Give two example of carbs that may not follow the normal ratio of H to O
Give two functions of carbs
State the types of carbs
State the types of carbs
Give two examples of disaccharides
Polysaccharides mainly serve as what kind of compounds?
What is the most important monosaccharide ?
What is it’s function?
What monosaccharide is most important as a component of coenzymes

A

Carbohydrates:
􏰀Biological molecules of carbon, hydrogen and
oxygen atoms with ratio of H to O = 2:1
􏰀 Cm(H2O)n (where m could be different from n)
􏰀 Some exceptions exist; E.g. deoxyribose, a sugar component of DNA, has the empirical formula
C5H10O4
􏰀 Source of energy and structural materials for organisms
􏰀 Storage: e.g., starch and glycogen
􏰀 Structural: cellulose in plants and chitin in arthropods

􏰀Carbohydrates comprising of :
􏰀 monosaccharides
􏰀 single molecules- glucose, fructose, galactose
􏰀 Oligosaccharides —few monosaccharides linked
together. 3-10 monosaccharides
􏰀 disaccharides – double molecules — bonding of two simple sugars so two
Monosaccharides
􏰀 - maltose — two glucose ,
􏰀 - sucrose — glucose + fructose ,
􏰀 - lactose) —– glucose + galactose

Polysaccharides
􏰀 Polymeric carbohydrates that include starches, glycogem, cellulose etc
􏰀 Mainly serve as storage compounds(These are complex carbohydrates known as polysaccharides, formed by linking large numbers of monosaccharides)

􏰀 Glucose (C6H12O6) is the most important monosaccharide, and basic fuel for living things

The 5-carbon monosaccharide ribose is an important component of coenzymes (e.g., ATP, FAD and NAD) and the backbone of the genetic molecule known as RNA.
􏰀 The related deoxyribose is a component of DNA.

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9
Q

How is starch,cellulose and glycogen formed
What are proteins
State the functions of proteins

A

Starch: Composed of hundreds or thousands of glucose units; serves as a storage form of carbohydrates in plants
􏰀 Glycogen: Important polysaccharide composed of glucose units, but combined differently from those in starch. It is the storage form of glucose in animals
􏰀 Cellulose: Primarily structural polysaccharide composed of glucose units, but only a few organisms can break it down to release glucose (found in wood, cotton fabric, paper, etc.)

Proteins:
􏰀 One of the most complex organic compounds, composed of amino
acids (composed of C, H, O and N atoms; also S, P, Fe and Cu)
􏰀 Differ from one another in their sequence of amino acids which usually results in folding of the protein into a specific three-dimensional structure that determines its activity.
􏰀 The sequence of amino acid residues in a protein is defined by the sequence of a gene, which is encoded in the genetic code.
􏰀 Peptide bonds link amino acids,
􏰀 A linear chain of amino acid residues is called a polypeptide.
􏰀 Short polypeptides, containing less than about 20-30 amino acis residues, are rarely considered to be proteins and are commonly called
peptides

Building blocks of life
􏰀 Required by all living things for strengthening and supporting
materials 􏰀 Functions:
􏰀 Used in production of enzymes, which catalyse biochemical reactions
􏰀 Structure (hair, horns, keratin, silk, actin and myosin in muscle )
􏰀 Transport- haemoglobin
􏰀 Defence-antibodies

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10
Q

What are lipids
Another name for glycerol is ?
Name two common lipids and three functions of lipids

A

Lipids:
CHEMICAL BASIS OF LIFE ORGANIC COMPOUNDS (3)
􏰀 Also composed of C, H, O atoms, but higher H:O ratio
􏰀 Molecules are composed of a glycerol molecule and 1-3 molecules of fatty acids
􏰀 A fatty acid is a long chain of carbon atoms (4-24) with a carboxyl (- COOH) at the end, while glycerol contains three hydroxyl (-OH) group

Another name is Glycerin

􏰀Common lipids include steroids (composition of hormones), waxes and fats
􏰀 Source of reserve energy supply to the organism
􏰀 Vitamins A, D, E, and K are fat-soluble, can only be digested,
absorbed, and transported in conjunction with fats.
􏰀 maintaining healthy skin and hair
􏰀 Serves as a useful buffer towards a host of diseases

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11
Q

How do cells communicate with the environment

State and define the four ways

A

MEMBRANE TRANSPORT
􏰀 Cells communicate with the environment in several ways:
􏰀 Diffusion: Movement of molecules from region of higher concentration
to one of lower concentration (concentration gradient);
Types are simple diffusion and then facilitated diffusion
􏰀 Osmosis: Movement of water from region of higher concentration to that of a lower concentration across a semi-permeable membrane
􏰀 Hypotonic? 􏰀 Isotonic?
􏰀 Hypertonic?
􏰀 Facilitated Diffusion: Diffusion assisted by certain proteins in the membrane, from a region of higher concentration to that of a lower concentration. Another name for facilitated diffusion is called passive transport since it doesn’t use energy but requires transport proteins
􏰀 Active Transport: Movement of a material by a protein across a
membrane from a lower concentration to that of a higher
concentration, with expenditure of energy by the cell (ATP)

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12
Q

􏰀Chemical reactions in all living cells operate in the presence of ?
What are they composed of?
What are the characteristics of enzymes?

A

􏰀Chemical reactions in all living cells operate in the presence of enzymes (biological catalysts):
􏰀 Composed of proteins,
􏰀 Names end in ‘ase’ (e.g. lipase, protease, etc.)

Characteristics:
1.Specificity:
particular enzyme catalyses only one reaction
2.Lowers activation energy barrier

3.Act on substrates to form end-products:
speed up reactions but remain unchanged at the end
4.Active site of an enzyme interacts with the substrate in ‘lock and key’ fashion (enzyme-substrate complex):
Enzyme-substrate reaction is fast and reversible

Characteristics of an Enzyme :
Speed up chemical reactions.
They are required in minute amounts.
They are highly specific in their action.
They are affected by temperature.
They are affected by pH.
Some catalyze reversible reactions.
Some require coenzymes.
They are inhibited by inhibitors
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13
Q

Many enzymes work with chemical co-factors or co-enzymes.
Give one example each and state which is organic and which is inorganic

Rate of enzyme catalysed reactions depends on what

A

co-factors (inorganic- Fe, Mn, Zn) or co-enzymes (organic e.g. biotin) The term “non-protein” is used to differentiate coenzymes from the proteins that make up enzymes themselves. Here’s why organic coenzymes are classified as non-protein:

  1. Chemical Composition: Coenzymes are small organic molecules that are not composed of amino acids like proteins. Instead, they are typically derived from vitamins or other organic compounds. Their chemical structures are diverse and often include functional groups that are crucial for their role as cofactors in enzyme-catalyzed reactions.
  2. Role in Enzyme Function: Coenzymes bind to enzymes temporarily, often at the enzyme’s active site or another specific binding site, to assist in the catalytic process. They may donate or accept electrons, atoms, or functional groups during reactions, thereby facilitating the conversion of substrates into products. This interaction is essential for the enzyme to function effectively in metabolic pathways.
  3. Regeneration and Reuse: Unlike proteins, which are typically synthesized and degraded in cellular processes, coenzymes are not permanently altered or consumed during enzymatic reactions. They can undergo reversible changes or cycles of association and dissociation with enzymes. This characteristic allows coenzymes to participate repeatedly in catalytic reactions, enhancing the efficiency and versatility of enzymatic processes.
  4. Origin: Many coenzymes are derived from vitamins or vitamin-like compounds. For example, coenzyme A (CoA) is derived from pantothenic acid (vitamin B5), while flavin adenine dinucleotide (FAD) and nicotinamide adenine dinucleotide (NAD+) are derived from riboflavin (vitamin B2) and niacin (vitamin B3), respectively. These organic molecules are synthesized by cells or obtained from the diet and play crucial roles as cofactors in numerous metabolic reactions.

􏰀 Rate of enzyme-catalysed reactions depends on several factors:
􏰀 Substrate concentration-increasing the substrate concentration increases the rate of
reaction, to a certain point
􏰀 Acidity and temperature of environment :Works best at optimum pH and temperature
􏰀 Presence of other chemicals:
1.Inhibitors –
Harmful… poisons
Useful …. Many drugs
2.Activators
􏰀 molecules that bind to enzymes and increase their activity

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14
Q
What is mitosis 
How many phases does it occur in
Name them
Name the three main functions of mitosis 
What is meiosis
How many phases does it occur?
Name each phase and the stages involved in each stage
State the main function of meiosis
A

Mitosis: Cell division which results in two daughter cells with the same number of chromosomes as the parental cell
􏰀 Occurs in five phases: Prophase, Metaphase, Anaphase, Telophase, Cytokinesis. Mitosis is the process by which cells divide to create two identical daughter cells. Here’s a simple explanation of its phases:

  1. Interphase: This is the phase before mitosis starts. The cell grows, copies its DNA, and prepares for division.
  2. Prophase: In prophase, the copied DNA coils up tightly into chromosomes. The nuclear membrane around the nucleus breaks down.
  3. Metaphase: The chromosomes line up in the middle of the cell. They attach to spindle fibers that stretch from one end of the cell to the other.
  4. Anaphase: The spindle fibers pull the chromosomes apart. Each half moves to opposite ends of the cell.
  5. Telophase: The separated chromosomes reach the ends of the cell. New nuclear membranes form around each set of chromosomes, creating two new nuclei.
  6. Cytokinesis: Finally, the cell pinches in the middle, dividing into two new daughter cells. Each daughter cell gets a copy of the chromosomes and other cell parts.

􏰀 Three main functions:
􏰀 Growth of Organisms
􏰀 Asexual reproduction in simple multicellular organisms
􏰀 Wound healing or regeneration of body parts
􏰀 Meiosis: Cell division resulting in halving of chromosome number during gamete formation (human diploid chromosome number of 46 converts into 4 haploid daughter cells each with 23 chromosomes)
􏰀 Occurs in two main phases:
􏰀 Meiosis I: Prophase I, Metaphase I, Anaphase I, Telophase I Cytokinesis I
􏰀 Meiosis II: Prophase II, Metaphase II, Anaphase II, Telophase II, Cytokinesis II
􏰀 Main function:
􏰀 Sexual reproduction in complex organisms

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15
Q

In mitosis ,what happens in each stage

A

Interphase- 46 chromosomes
Prophase- chromosomes double to 92
Prometaphase-nucleus dissolves and microtubules attach to centromeres
Metaphase- chromosomes align at middle of the cell
Anaphase-separated chromosomes pull apart
Telophase- microtubules disappear and cell division occurs
Cytokinesis- two daughter cells formed each with 46 chromosomes

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16
Q

In meiosis what happens in each stage

A

Interphase 1-46 chromosomes
Prophase 1-chromosomes double to 92
Prometaphase 1-nucleus dissolves and microtubules attach to centromeres
Metaphase 1-chromosomes align at middle of the cell
Anaphase 1-separated chromosomes pull apart
Telophase 1-microtubules disappear and cell division occurs
Interphase 2- two cells formed each with 46 chromosomes
Metaphase 2- microtubules attach to centromeres
Anaphase 2- chromosomes pulled apart to 23
Telophase 2- microtubules disappear and cell division begins
Cytokinesis- 4 cells formed each with 23 chromosomes

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17
Q

Who is the father of genetics and when did he perform his experiments
What plant did he perform it on
Why will we say he was lucky?

A

Gregor Mendel: Augustinian Monk- Father of Genetics, performed experiments in the 1860s and 1870s

Garden pea or Pisum sativum

Was mendel lucky?
1.
2. 3. 4.
5.
6.
􏰀
P. sativum were cheap, grow easily and have short life cycles: 3 generations in a year.
The male and female reproductive parts of the f lower were distinguished and large enough for crossing experiments.
Cross pollination rarely took place which means that selfing the plants were easily established.
The seven traits that mendel chose were present on different loci and moreover they showed distinguished phenotypic characteristics.
P. sativum plant produces large number of f lowers and each f lower when crossed would produce pods containing between 2-8 peas
The seven traits that Mendel chose were dominant traits.
co-dominance and incomplete dominanace were discovered
much later, and caused a lot of confusion for a long time. Mendel
was lucky not to come across them
GEMP Tutorial

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18
Q

What is a gene,allele,gene flow,homogous chromosomes,genome,genotype,phenotype,homozygous allele,heterozygous allele,dominant allele,recessive allele,locus

A

Gene: Fundamental physical unit of heredity (now known to contain DNA in chromosomes)
􏰀 Allele: Different forms (2 or more) or varieties of a gene occupying the same locus on homologous chromosomes. An allele is a different version of the same gene. For example, consider the gene for flower color in a plant species. If this gene can produce either red flowers or white flowers, then the red flower version of the gene is one allele, and the white flower version is another allele. An allele can be heterozygous or homozygous. Heterozygous example is having a gene for hair color with an allele being black and another being white then homozygous is the same gene for color but the alleles are all black for both. So homologous chromosome,look for the explanation in one of the cards. It’ll make this card too long.
􏰀 Gene flow: transfer of alleles or genes from one population to another.
􏰀 Homologous chromosomes: Pair of chromosomes containing the same genetic information
􏰀 Genome: Set of genes specifying an organism’s traits (100,000 in humans); total genetic information an individual inherits from its parents
􏰀 Genotype: Genetic composition/constitution of an organism
GEMP Tutorial 34

􏰀 Phenotype: Outward expression/observable manifestation of specific genotype 􏰀 Homozygous: Two identical alleles present for a particular characteristic (true-breeding) 􏰀 Heterozygous: Two different alleles present for a particular characteristic 􏰀 Dominant Allele: Expressed allele when two are present 􏰀 Recessive Alleles: Overshadowed allele which is only expressed when both are present 􏰀 Locus: Location of a gene on a chromosome
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19
Q

State Mendel’s three laws of genetics

A

􏰀 Complete Dominance: When an organism has two different alleles for a trait, one allele dominates. Example-Dominance**: for skin let’s say we have two alleles B and b. If black (B) is dominant over fair (b), individuals with genotype BB or Bb would exhibit black skin color.
- Recessive: If fair (b) is recessive, individuals would need to have the genotype bb to exhibit fair skin color.

􏰀 Segregation: During gamete formation by a diploid organism, the pair of alleles for a particular trait separate, or segregate, during gamete formation (meiosis) or Mendel’s law of segregation states that during the formation of gametes (sex cells), the two alleles for a gene segregate or separate from each other such that each gamete carries only one allele for each gene.
􏰀 Independent Assortment: Members of a gene pair separate from one another independently of the members of other gene pairs.
The Law of Independent Assortment applies only when the genes are located on different chromosomes or are far apart on the same chromosome (due to genetic recombination).
So I think the assortment means the genes are randomly assigned to the baby during meiosis and the independent means just because when the sharing was going on, you got big butt gene doesn’t mean you’ll get big boobs too. You getting big boobs gene doesn’t depend on you getting big butt gene.
, “assortment” refers to the random distribution or segregation of alleles (alternative forms of a gene) into gametes during the process of gamete formation (meiosis).

  1. Law of Independent Assortment:
    • This principle, proposed by Gregor Mendel, states that alleles of different genes segregate (separate) independently of each other during the formation of gametes.
    • In other words, the inheritance of one trait (determined by one gene) does not affect the inheritance of another trait (determined by a different gene) when those genes are located on different chromosomes or are far apart on the same chromosome (due to crossing over).

. Sure, let’s explain the Law of Independent Assortment to a 6-year-old in a simple and relatable way:

Imagine you have a box of colorful blocks. Some blocks are red, and some are blue. You also have two baskets to sort these blocks. One basket is for red blocks, and the other is for blue blocks.

Now, when you start putting blocks into the baskets, you close your eyes and pick one block at a time from the box. You don’t look at which color you picked before. You just put each block into its basket based on its color.

The Law of Independent Assortment is a bit like that. It says that when our body makes tiny cells called “egg” or “sperm,” the colors (or traits) they get can be mixed up in a random way. So, if our body has two traits to decide on (like eye color and hair color), they can get mixed up in different ways. This randomness helps make sure that kids can look a bit like their mom or dad or even their grandparents, but also be a little bit different too!

Just like how you randomly sort blocks into baskets, our body sorts traits into new cells in a way that makes each person unique, with a mix of traits from their family.

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20
Q

State the eight principles of genetics and explain four

A mother with type B blood has a type A baby. The husband is refusing paternity. Is he justified?
􏰀
􏰀 A couple had a baby and were worried that it did not resemble either of them. The baby’s blood type is O, the father is type A , and the mother is type B. Are they right to conclude that there had been a mix-up at the hospital? Explain.

A

Incomplete Dominance: In some combinations, dominant alleles do not exist, rather the two alleles blend and both alleles have the opportunity to express themselves (combined expression of two different alleles)(example is in the biology slides) example is have a white gene for a flower and a red gene for another. Instead of having either red or white flowers when they are crossed, they have pink flowers. They don’t have red or white. It’s a blend of the two colors. Neither of the colors are completely dominant over the other. Rather there is a born of the red and white gene.

  1. Codominance: Where both alleles are completely expressed (e.g.
    ABO blood system) In individuals with the genotype IAIB, both A and B alleles are expressed equally, resulting in the blood type AB. This means both A and B antigens are present on the surface of red blood cells. This expression of both alleles in the phenotype without blending is the hallmark of codominance.another example is seeing two different patches of colours on the skin of an animal

3.Linkage: Sometimes, a large number of genes are inherited together, because they are located on the same chromosome. The closer the genes are to each other, the higher the probability that they will be inherited together

  1. Multiple Alleles: When more than two alleles exist for a particular characteristic
    􏰀 E.g. Human blood groups- A, B, O, where A and B are co- dominant, but both are dominant over O
    􏰀 Thus: Type A (AA and AO); Type B (BB and BO); Type AB (AB) ; Type O (OO)
  2. polygenic inheritance
  3. pleiotrophy
  4. epistasis
  5. sex linkage
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21
Q

Explain polygenic inheritance

  1. pleiotrophy
  2. epistasis
  3. sex linkage as principles of genetics
A

􏰀Polygenic Inheritance (Multiple Genes): When some characteristics are determined by interaction of genes on several chromosomes, or by several genes on the same chromosome (e.g. skin colour in humans, height, etc.)
􏰀 Pleiotropy: When a single gene has more than one phenotypic expression
GEMP Tutorial 41

􏰀 Epistasis: When one gene affects the phenotypic expression of another e.g. pigmentation in mice- one gene: 􏰀 The wild-type coat colour, agouti (AA), is dominant to solid- coloured fur (aa). 􏰀 A separate gene (C) is necessary for pigment production. 􏰀 A mouse with a recessive c allele at this locus is unable to produce pigment and is albino regardless of the allele present at locus A. 􏰀 Therefore, the genotypes AAcc, Aacc, and aacc all produce the same albino phenotype  GEMP Tutorial 42

PRINCIPLES OF GENETICS (3) 􏰀 Sex Linkage 􏰀 Of the 23 pairs of human chromosomes, one pair is referred to as the sex chromosomes, while the other 22 pairs are the autosomes 􏰀 Two types of sex chromosomes, X and Y; females have XX and males have XY (i.e., male genotype: 44XY; female genotype: 44 XX) 􏰀 The Y chromosome is shorter than the X, causing sex-linked inheritance 􏰀 Certain sex-linked genes reside on the X-chromosome; such a gene will have both alleles in the female, but since the Y chromosome is shorter, some of these genes will be expressed in the male, whether recessive or dominant, since they may not have counterparts in the male 􏰀 Thus, some genes may not be expressed in the female because they are recessive, but they may be expressed in the male because the dominant allele may be absent (e.g. colour blindness, haemophilia) Color blindness, or color vision deficiency, is a genetic condition that primarily affects the ability to perceive differences in colors. It is most commonly inherited in an X-linked recessive pattern, meaning the gene responsible for the condition is located on the X chromosome. Here’s how it works:
  1. X-linked Inheritance: The genes that determine color vision are located on the X chromosome. Females typically have two X chromosomes (XX), while males have one X and one Y chromosome (XY). Since the gene for color vision deficiency is recessive and located on the X chromosome, males are more likely to be affected because they only inherit one X chromosome.
  2. Expression in Males: If a male inherits an X chromosome with the color vision deficiency gene (X^c) from his mother (who may be a carrier), and since males have only one X chromosome, they will express the trait if the X chromosome they inherit carries the color blindness allele. This makes males more susceptible to color blindness.
  3. Expression in Females: Females can be carriers of color blindness if they inherit one normal allele (X^C) and one color blindness allele (X^c). Typically, females are not color blind themselves because they have a second X chromosome with the normal allele, which usually masks the effects of the recessive allele. However, some females with a color blindness allele on one X chromosome and no normal allele on the other X chromosome can also be color blind
22
Q

What is evolution
What did Aristotle say about it?
How did James Ussher oppose this thing Aristotle said?
What James said was opposed by which three people?
State the three evolution theories Jean-Baptiste Lamarck (French Zoologist) is associated with

A

Definition and History
􏰀 A change in one or more characteristics of an organism over a period of
time
􏰀 Aristotle (Greek philosopher) perceived a ‘ladder of life’ where simple organisms gradually change into complex forms
􏰀 James Ussher opposed this by reference to the Bible (Genesis) and deduced that creation started on 22 October 4004 BC at 6.00 pm
􏰀 Creationism opposed by geologists- James Hutton, Georges Cuvier and Charles Lyell- the earth was far older than Ussher’s estimate
􏰀 Jean-Baptiste Lamarck (French Zoologist)- Theories of:
􏰀 ‘Use and Disuse’: Development with increased usage
􏰀 ‘Inheritance of Acquired Characters’:
􏰀 ‘Natural Transformation’: Increasing complexity with the
generations, with no extinction or speciation

23
Q

Who brought the theory of natural selection
What does this theory say?
Why does population remain stable?

A

Charles Darwin (English naturalist)- Theory of Natural Selection:
􏰀 Differences in survival and reproduction among individuals in a
population because of interaction with the environment
􏰀 Rapid rate of population increase (e.g. 2 elephants can produce 19 million individuals in 750 years if all offspring survive)
􏰀 Population remains stable because resources are limited-Limited Resources**: Natural resources such as food, water, and shelter are limited. This limitation means that not all individuals in a population can survive and reproduce, leading to a stable population size.

  1. Carrying Capacity: The environment has a carrying capacity, which is the maximum population size that it can support sustainably. When the population exceeds this capacity, the death rate increases due to factors like starvation, disease, and competition, reducing the population back to a stable size.
    3.Reproductive Success**: In natural selection, individuals with advantageous traits are more likely to survive and reproduce
    􏰀 There is random variation among living things which is heritable
    􏰀 There is a struggle for existence (competition)
    􏰀 Survival of the fittest (environment selects individuals better able
    survive)
    􏰀 Evolution of new species

The law of natural selection, proposed by Charles Darwin, explains how species evolve over time through the differential survival and reproduction of individuals with advantageous traits. Here’s a brief explanation:

  1. Variation: Within a population, individuals have different traits due to genetic variation.
  2. Competition: Resources such as food, shelter, and mates are limited, leading to competition among individuals.
  3. Survival of the Fittest: Individuals with traits that give them an advantage in their environment are more likely to survive and reproduce.
  4. Reproduction: These advantageous traits are passed on to the next generation.
  5. Adaptation: Over many generations, these traits become more common in the population, leading to gradual adaptation to the environment.

In essence, natural selection is the process by which beneficial traits become more prevalent in a population, driving the evolution of species.

24
Q

As evidences of evolution what is paleontology,comparative anatomy(state what homology,analogy and vestigial organs are),comparative embryology,comparative biochemistry (molecular biology),geographical distribution (biogeography)

A

Palaeontology
EVOLUTION (2) EVIDENCE
􏰀 Fossilized bones, shells, teeth, other human remains- evidence of descent of modern organisms from common ancestors (evidence of extinct organisms)

Comparative Anatomy
􏰀 Homology: same structure, different functions (e.g. forelimbs of humans,
whales, bats)- adaptive radiation, divergent evolution
􏰀 Analogy: different structure, same functions (e.g. wings of bat, bird)-
convergent evolution
􏰀 Vestigial Organs: ‘useless’ organs in organisms which are used by other
organisms (e.g. appendix, coccyx, etc.)

Comparative Embryology
􏰀 Striking similarity among embryos of complex animals
(fishes → mammals)
􏰀 Comparative Biochemistry (Molecular Biology)
􏰀 Biochemical similarity in all living things (DNA, RNA,
genetic code)- Chimp/Human
􏰀 Geographical Distribution (Biogeography)
􏰀 Occurrence of particular animals at some places and nowhere else (e.g. marsupials of Australia, Galapagos giant tortoises)

25
Q

State and explain the two main types of biological associations and the types under them

A

Beneficial Interactions (Cooperation):
􏰀 Commensalism: One species benefits, the other not affected (e.g. whales -
remora)
􏰀 Protocooperation: Both species benefit, but association not obligatory (cattle egret – cattle)
􏰀 Mutualism: Both species benefit, association obligatory (ruminant – microbes)

􏰀 Detrimental Interactions (Disoperation):
􏰀 Parasitism: One species (parasite) benefits, the other (host) is harmed. There are ectoparasites (lice, bedbugs, fleas) and endoparasites (tapeworm)
􏰀 Predation: One species (predator) kills and feeds on another (prey)
􏰀 Competition: Two or more species compete for a resource (e.g. food,
shelter, mates) in short supply
􏰀 Direct Competition: Active antagonism/combat between individuals
􏰀 Indirect Competition: One species monopolizes a resource and renders a habitat
unsuitable for other organisms with identical requirements

26
Q
What four things do animals in the same species or animals of different species have to compete for?
What is reproduction 
What is sexual and asexual reproduction 
Which is meiosis and which is mitosis 
What are the reproductive strategies?
Define them
A

food water space mates

Reproduction: Ability to generate new organisms from pre- existing ones
􏰀 Sexual Reproduction: Reproduction involving pairing of two gametes (male and female) to produce a zygote, which develops into a new individual. An individual offspring thus inherits genes from two parents
􏰀 Asexual Reproduction: Reproduction without formation of gametes (i.e., no sexual interaction). An individual offspring is thus genetically identical to, or is a clone of its parent (e.g. budding, binary fission, etc.)

Sexual- meiosis
Asexual- mitosis

Oviparity: Egg-laying, with eggs developing outside mother’s body (invertebrates, fishes, amphibians, reptiles, birds)
􏰀 Ovoviviparity: Young develop from eggs retained within mother’s body, but not nourished by mother (some insects, fish, reptiles). Ovoviviparity is a way some animals reproduce. Here’s a simpler explanation:

  1. Eggs Inside the Mother: The mother keeps the eggs inside her body instead of laying them outside.
  2. Development: The embryos grow and develop inside these eggs.
  3. Hatching: When the young are ready, they hatch from the eggs while still inside the mother.
  4. Birth: The mother then gives birth to the live young, who have already hatched from their eggs.

So, it’s a mix between laying eggs (like birds) and giving live birth (like humans). The eggs stay inside the mother until the babies are ready to be born.
􏰀 Viviparity: Young produced at a stage of development in which they are active; embryo occurs within mother’s body which nourishes it (placenta, umbilical cord present) (placental mammals)
􏰀 External Fertilization: Gametes unite outside body (most aquatic animals)
􏰀 Internal Fertilization: Gametes unite within female body (most terrestrial animals)

oviparity is the trait of laying eggs, while ovoviviparity is the development of embryos inside eggs that are retained within the mother’s body until they are ready to hatch, and viviparity is giving birth to young ones directly

Ovoviviparous animals are similar to viviparous species in which there is internal fertilization and the young are born alive, but differ in that there is no placental connection and the unborn young are nourished by egg yolk; the mother’s body does provide gas exchange.

27
Q

State the six characteristics of living things

A

CHARACTERISTICS OF LIVING THINGS
􏰀 Cellular organization (made of cells that contain DNA)
􏰀 Metabolism (acquisition/use/transfer of energy for activities)
􏰀 Growth and development
􏰀 Homeostasis (regulation of body systems) 􏰀 Reproduction (sexual/asexual)
􏰀 Response/adaptation to environment
To be considered alive, an object must exhibit all of the characteristics of living things.

28
Q

One way to make sense of the diversity of organisms is by classification
True or false

What did Linné (Carolus Linnaeus) , Ernst Haeckel (1880s) , Robert Whittaker (1968) propose under kingdoms of life ?
What are the seven hierarchical levels of classifications
What is binomial nomenclature and give examples

A

􏰀 Linné (Carolus Linnaeus) originally recognized two kingdoms- Plantae (plants) and Animalia (animals)
􏰀 Ernst Haeckel (1880s) proposed a three-kingdom system- Animalia, Plantae (mosses, ferns, spermatocytes) and Protista (protozoa, algae, fungi, bacteria, etc.)
􏰀 Robert Whittaker (1968) proposed five kingdoms, which is currently the most-widely accepted: Animalia, Plantae, Protista, Fungi (yeasts, molds, mushrooms, etc.), and Monera (prokaryotes- bacteria, cyanobacteria)

Kingdom
Phylum
Class
Order
 Family
Genus 
Species

The Linnaean system uses two Latin name
categories, ‘genus’ and ‘species’ to classify each type of organism.
Such a dual level designation is referred to as a binomial nomenclature. For example, Linnaeus described humans in his system as Homo sapiens.
• Homo is our genus and sapiens is our species.

29
Q

Name some reasons for a standardized nomenclature ?

What is the INTERNATIONAL CODE OF ZOOLOGICAL NOMENCLATURE (ICZN) and state the rules of zoological nomenclature

A

Common (vernacular) names differ from country to country or from region to region within the same country, hence need for a universally-accepted scientific name
􏰀 Some common names do not provide any clues about the animal under reference, making its identification difficult:
􏰀 John Dory (Zeus faber)- Bony Fish
􏰀 Prairie Dog (Cynomys parvidens)- American Squirrel
􏰀 Sergeant-Major (Abudefduf saxatilis)- Bony Fish
􏰀 River Jack (Bitis nasicornis)- Rhinoceros Viper (Snake) 􏰀 Water Mocassin (Ancistrodon piscivorus)- pit viper

INTERNATIONAL CODE OF ZOOLOGICAL NOMENCLATURE (ICZN)
􏰀 Ratified in Berlin (1901); 88 article, 338-page document
􏰀 Sought to ensure that all zoologists recognise only one scientific name for a
particular species, to avoid confusion 􏰀 Rules of zoological nomenclature:
􏰀 Binomen should be in Latin, so must always be italicized or underlined
􏰀 Generic name is always initially capitalized, while the specific name is not (e.g.
(Homo sapiens, Panthera leo)
􏰀 Each binomen should describes only one species
􏰀 Binomens can be abbreviated if already mentioned in a document (e.g. H. sapiens, P. leo)
􏰀 Family names always end in “-idae”; subfamily names end in “inae”, and superfamily names end in “oidea”

30
Q

What are the five kingdoms of life and give some examples under each
Name 9 phylums and give the distinct characteristics of each

A

FIVE KINGDOMS OF LIFE
􏰀 Monera: One-celled prokaryotic organisms without nuclei or organelles in their cytoplasm, have a single chromosome, small ribosomes, and reproduce by binary fission
􏰀 Protista: One-celled eukaryotic organisms, which can be autotrophic or heterotrophic, Protists are a diverse group of eukaryotic microorganisms that exhibit a wide range of nutritional strategies. Here’s an explanation of autotrophic and heterotrophic protists:

  1. Autotrophic Protists:
    • Definition: Autotrophic protists are organisms that can synthesize organic compounds (such as carbohydrates) from inorganic substances using external energy sources.
    • Examples: Many autotrophic protists are photosynthetic, utilizing light as their primary energy source to convert carbon dioxide and water into glucose and oxygen. Examples include:
      • Diatoms: Photosynthetic protists with silica shells, abundant in aquatic environments.
      • Dinoflagellates: Photosynthetic protists that often have two flagella and are common in marine ecosystems.
      • Euglenoids: Protists that can be autotrophic or heterotrophic, possessing chloroplasts and often found in freshwater habitats.
  2. Heterotrophic Protists:
    • Definition: Heterotrophic protists obtain their nutrition by ingesting or absorbing organic molecules produced by other organisms.
    • Examples: Heterotrophic protists can be further categorized based on their feeding strategies:
      • Phagotrophs: These protists ingest particles of food through phagocytosis. Examples include amoebas and some flagellates.
      • Osmotrophs: These protists absorb nutrients directly from their environment through osmosis. Examples include many parasitic protists and some free-living amoebas.
      • Mixotrophs: Some protists are capable of both autotrophic and heterotrophic nutrition, depending on environmental conditions. They may switch between photosynthesis and phagocytosis as needed..
        In summary, protists exhibit diverse nutritional strategies, with autotrophic protists capable of photosynthesis and heterotrophic protists relying on external sources of organic matter. )possess nuclei and organelles in their cytoplasm, multiple chromosomes, large ribosomes, and reproduce by meiosis

􏰀 Fungi: Eukaryotic and heterotrophic organisms, multicellular (few unicellular), chitinous or cellulose cell wall
􏰀 Plantae: Autotrophic (photosynthetic), eukaryotic and multicellular organisms
􏰀 Animalia: Heterotrophic, eukaryotic, multicellular, no cell wall

Phylum: PORIFERA (Sponges)
􏰀 Body consists of specialized cells not organized into tissues or organs
􏰀 Asymmetrical bodies(you can’t divide the bodies into two equal parts)

􏰀 Phylum: CNIDARIA (Jellyfish, Hydra, Sea Anemone, Coral)
􏰀 Carnivorous, radial symmetry
􏰀 Possess tentacles

􏰀 Phylum: PLATYHELMINTHES (Flatworms, Planaria, Taenia) 􏰀 Acoelomate, bilateral symmetry
􏰀 No circulatory system
􏰀 Only one opening- mouth (no anus), most parasitic
No body cavity

􏰀 Phylum: NEMATODA (Roundworms, Ascaris) 􏰀 Pseudocoelomate, bilateral symmetry
􏰀 Most microscopic, soil-living
􏰀 Most parasitic
Have a false body cavity

Phylum: ANNELIDA (Segmented worms, earthworms, polychaetes) 􏰀 Coelomate, metameric segmentation
􏰀 Bilateral symmetry
􏰀 Phylum: MOLLUSCA (Gatropods, bivalves, cephalopods) 􏰀 Coelomate, circulatory system
􏰀 Shelled
􏰀 Phylum: ARTHROPODA (Arachnids, crustaceans, insects, myriapods) 􏰀 Jointed appendages, chitinous exoskeleton
􏰀 Segmentation
􏰀 Largest animal phylum
􏰀 Phylum: ECHINODERMATA (Starfishes, sea urchins)
􏰀 Endoskeleton
􏰀 Radial symmetry

PHYLUM: CHORDATA
• Characteristics of the Chordates
1. Notochord- rod like structure runs through the entire organism
2. Dorsal hollow nerve cord
3. Pharyngeal gill slits
4. Post anal tail
(Look at the parts of the chordates in the slides)

Remember: To remember the main six animal phyla, you can use the following mnemonic:

“Porcupines Can Pluck Nuts And Eagerly Eat”

Here’s how it breaks down:

  1. Porifera (Sponges)
  2. Cnidaria (Jellyfish, Hydra, Sea Anemone, Coral)
  3. Platyhelminthes (Flatworms, Planaria, Tapeworms)
  4. Nematoda (Roundworms, Ascaris)
  5. Annelida (Segmented worms, Earthworms, Polychaetes)
  6. Echinodermata (Starfish, Sea Urchins)

This mnemonic uses the first letter of each phylum to help you remember the sequence easily. Adjust as needed to fit your learning style and preferences!

31
Q

What are the types of chordates and give one example each

Name six classes and give their distinct features and examples of organisms

A
  1. Protochordates
    􏰀 Notochord persists through out life or it completely degenerates

2.Vertebrates (Subphylum Vertebrata)
􏰀 notochord of vertebrates is replaced by the spinal column composed of cartilage, bone or both, which tend to protect the dorsal nerve cord.
􏰀 have their brain enclosed in a cranium. 􏰀 Approximately 43,700 living species

Class: AGNATHA (Jawless vertebrates; lampreys, hagfishes) 􏰀 Cylindrical elongated bodies; no paired appendages
􏰀 Jawless; suctorial mouth; horny teeth
􏰀 Cartilaginous skeleton
􏰀 Class: CHONDRICHTHYES (Cartilaginous fishes; sharks, rays, skates) 􏰀 Cartilaginous skeleton; no operculum (exposed gill slits)
􏰀 Ventral mouth; heterocercal tail
􏰀 Class: OSTEICHTHYES (Bony fishes; Tilapia) 􏰀 Bony skeleton; operculum present
􏰀 Terminal mouth; homocercal tail
􏰀 Class: AMPHIBIA (Amphibians- frogs, toads, salamanders, caecilians) 􏰀 Soft, glandular, scale-less skins, cutaneous respiration
􏰀 Indirect development (metamorphosis), early larval stage
􏰀 External fertilization, oviparity

Class: REPTILIA (Crawling vertebrates- lizards, snakes, chelonians, crocs)
􏰀 Dry scaly skin
􏰀 Shelled, cleidoic eggs
􏰀 Internal fertilization with intromittent organ 􏰀 Direct development (no larval stage)
􏰀Class: AVES (Birds- flightless birds: ostriches, flying birds)
􏰀 Scales modified into feathers for flight
􏰀 Forelimbs modified into wings
􏰀 Elaborate air-sac system; pneumatic bones, four-
chambered heart

Class: MAMMALIA (Mammals- monotremes, marsupials, placentals)
􏰀 Distinguishing features
􏰀 All mammals have mammary gland
􏰀 All mammals have hair
􏰀 The lower jaw in mammals is a single bone
(Notice the distinction in the shapes of the teeth in mammals and reptiles)

32
Q

The mammalian middle ear consists of three bones
Name them
In mammals what artery becomes the aortic arch and how?
In birds the main artery leaving the heart curves where?

􏰀 In other vertebrates, there are more than one main artery leaving
the heart.
􏰀 Mammalshaveadiaphragm true or false
Name three other characteristics that will show an animal is a mammal

A

The mammalian middle ear contains 3 bones
􏰀 Stapes (or Stirrup),
􏰀 Incus (or Anvil)
􏰀 Malleus (or Hammer)

They are the (From outside the ear to inside, you meet the hammer, called the malleus first ; then the anvil, known as the incus; and the last bone is the stirrup, known as the stapes. ) The eardrum lies between the middle ear and outer ear. The middle ear connects to the back of the nose and throat by a narrow area called the eustachian tube.

Inmammals,themainarteryleavingtheheartcurvesto the left and becomes the aortic arch.
􏰀 In birds, the main artery leaving the heart curves to the right.

Other characteristics which are sure indicators that an animal is a mammal, but which may not be present in all mammals include:
1.The possession of a placenta in the females which allows the mother’s system to nourish the growing young.
2.Two sets of teeth (diphyodont dentition):
􏰀 Reptiles and fish have many sets and can replace lost teeth with new ones all their lives
3.Mammals are heterodontic:
􏰀 their teeth are of different shapes, except those with no teeth. incisors, canines, molars and premolars.
􏰀 Reptiles and fish have teeth that are all basically the same, though they can vary in size

33
Q

What is digestion?
Name the organs of digestion in the alimentary canal
What comprises of the mouth and what does the mouth do in digestion?
What does saliva contain?
What is the function of the oesophagus?
What is peristalsis?
Function of the stomach
What do goblet cells produce?
From the esophagus to the anal canal, the walls of every organ of the alimentary canal are made up of the four basic layers. Name them
What is the pH of the gastric juice in the stomach? When is gastric juice secreted?
What are the contents of gastric juice

A

The hydrolytic breakdown of food, which consists primarily of large molecules, into smaller ones which are readily soluble in water and can therefore be easily absorbed through the mucous membrane of the gut

Alimentary Canal: Main organ of digestion, from mouth to anus
􏰀 Mouth (Reception, ingestion, ptyalin(this is also called salivary amylase which converts starch to maltose and dextrins through hydrolysis where water molecules break down the glycosidic bonds between starch molecules) )
􏰀 Buccal cavity (Liquefaction,(process of converting solid food into liquid form that can easily be swallowed), mucus)
􏰀 Oesophagus (Passage)
􏰀 Stomach (Storage, chyme(chyme is food mixed with gastric acid and enzymes while bolus is when saliva mixes with the food in the mouth to form a soft mass), gastric juice)
􏰀 Duodenum (Bile, pancreatic juice, gall bladder, pancreas)
􏰀 Ileum (Absorption,, hepatic portal vein, liver)
􏰀 Colon
􏰀 Rectum
􏰀 Anus (Egestion)

􏰀 MOUTH:
Teeth, tongue, saliva- chemical/physical change to food (bolus)
Saliva: Contents:
􏰀 Water (lubrication)
􏰀 Mucin (lubrication
􏰀 Mineral salts (NaCl, PO42-, CO32-, Ca, K)
􏰀 Ptyalin (Salivary amylase): Cooked starch to maltose

OESOPHAGUS
􏰀 Walls secrete mucin for lubrication,
􏰀 Peristalsis: Rhythmic relaxation/contraction of oesophageal walls
􏰀 STOMACH
􏰀 Muscular sac for food storage and conversion to chyme
􏰀 Cardiac and pyloric sphincters
􏰀 Goblet cells produces mucus, protects tract
No stomach means no storage of food

Serosa, muscularis, submucosa, and mucosa

􏰀 Gastric Juice (pH= 1.5-2.5): Secreted after stimulation by gastrin
􏰀 HCl (dilute): Acidic medium (activator); disinfectant
􏰀 Water (98 %), mucin- lubrication, chyme
􏰀 Pepsin: Proteolytic enzyme (pH = 1.2)- secreted as pepsinogen (inactive)- converts proteins to polypeptides
􏰀 Rennin: Proteolytic enzyme - secreted as pro-rennin (inactive)- converts milk protein (caseinogen) to paracasein (curd). ‘Rennin curdles milk’

34
Q

In the duodenum,what is the pH of pancreatic juices?
When is the pancreatic juice secreted?
What are the contents of pancreatic juice and their functions
What is the pH of bile? Function of bile? Components of bile and their functions ?
What juice does the ileum produce?
What are the components of the juice produced.? What are their functions ?

A

DUODENUM
􏰀 Pancreatic Juice (pH= 8): Secreted by pancreas through pancreatic duct
􏰀 NaHCO3: Neutralises acidic contents of duodenum to produce basic medium
􏰀 Trypsin/Chymotrypsin: Proteolytic enzymes secreted as trypsinogen/ chymotrypsinogen, activated by enterokinase. Continued protein digestion
􏰀 Pancreatic amylase: Converts starch/glycogen to dissaccharides (e.g. maltose)
􏰀 Pancreatic lipase: Converts fats to fatty acids and glycerol

DUODENUM (CONTD.)
􏰀 Bile (pH= 7.5): Secreted by gall bladder through bile duct .. emulsifies lipids
􏰀 NaHCO3: Neutralises stomach acid
􏰀 Bile Salts: Sodium taurocholate/glycocholate) (0.8 %)
􏰀 Bile pigments: Bilirubin, biliverdin (products of haemoglobin breakdown) (0.2 %) 􏰀 Cholesterol (0.06 %)
􏰀 Mineral salts (0.7 %)
􏰀 Water (98 %), mucin

􏰀 ILEUM
Intestinal Juice (Succus Entericus)
Erepsin: Mixture of several proteases (peptidases)- peptides to amino acids
Amylases:
􏰀 MALTASE: Maltose (malt sugar) —– glucose + glucose
􏰀 SUCRASE (INVERTASE): Sucrose (cane sugar) …… glucose + fructose 􏰀 LACTASE: Lactose (milk sugar) ——- glucose + galactose
􏰀 LIPASE: Fats ——— fatty acids + glycerol

35
Q

What is responsible for increasing surface area in the ileum?
How is fat,carbs,protein,water, absorbed by the body?
What is assimilation?
How are proteins ,carbs,fats assimilated
The caecum is large in which animals?
Caecum is the site of which bacteria and what’s their function?
Where does caecum end?
What is the importance of the colon?
What is the function of the rectum?
What controls far all evacuation in adult humans?

A

ABSORPTION
􏰀 Villi/Microvilli: Expanded finger like projections in ileum to increase surface area
􏰀 Fat: Absorbed as fatty acids and glycerol, then to liver through hepatic portal vein OR in lacteals and lymphatic system, then blood
􏰀 Carbohydrate: Absorbed as monosaccharides (e.g. glucose) to liver
􏰀 Protein: Absorbed as amino acids
􏰀 Water: Absorbed by osmosis. More water absorbed in colon
􏰀 ASSIMILATION
􏰀 Incorporation of products of digestion into complex animal constituents .(Assimilation in digestion refers to the process by which nutrients from digested food are absorbed into the bloodstream and utilized by cells throughout the body)
􏰀 Proteins: Sent to liver, then body parts; excess excreted (deamination. This is when NH2 is removed from amino acid to get NH3(ammonia))
􏰀 Carbohydrate: Stored as glycogen in liver
􏰀 Fats: Deposited immediately in fat storage regions of body

CAECUM
􏰀 Large in true herbivores (e.g. rabbits, guinea-pig, sheep)
􏰀 Site of symbiotic bacteria, which digest cellulose in ruminants
􏰀 Ends in appendix (vestigial in humans)
􏰀 COLON
􏰀 No digestive function
􏰀 Important for water resorption by converting digestive residue into semi-solid faeces
􏰀 RECTUM
􏰀 No digestive function
􏰀 Further hardening of faeces for egestion through defaecation
􏰀 Peristaltic movements push faeces towards anal canal
􏰀 External anal sphincter controls faecal evacuation in adult humans

36
Q

What is blood?
State the functions of blood
What is the composition of blood?
Name the types of blood cells and their characteristics and their functions

A

BLOOD : Specialised connective tissue consisting of plasma and cells
􏰀 Functions:
􏰀 Transport of O2 from lungs to tissues, and CO2 in the reverse direction
􏰀 Removal of waste metabolites (e.g. urea)
􏰀 Thermoregulation
􏰀 Defence against infection
􏰀 Transport of end-products of digestion (glucose, amino acids, fatty acids)

Composition (Plasma): 􏰀 Water (90 %) 􏰀 Soluble proteins 􏰀 Albumins, globulins (blood buffers against radical pH changes)  􏰀 Fibrinogen, prothrombin (blood clotting) 􏰀 Food solutes (glucose, amino acids, fatty acids, glycerol)  􏰀 Excretory products (urea, uric acids, ammonia) 􏰀 Inorganic salts (Na+, Cl-, HCO3, K+, SO42-) and gases (O2, CO2, N2) 􏰀 Hormones

BLOOD CELLS 􏰀 Erythrocytes (Red Blood Cells) 􏰀 Non-nucleated, biconcave discs, haemoglobin, ions (Na+, K+, Mg2+, Ca2+, etc.)  􏰀 Approximately 25 billion in the human body 􏰀 About 7.5 μm diameter; 3 μm thick 􏰀 Transport of O2 and CO2

􏰀 Leucocytes (White Blood Cells)
􏰀 Nucleated, amoeboid
􏰀 Different types (polymorphs, neutrophils, lymphocytes, eosinophils, monocytes, neutrophils, basiphils)

􏰀 Thrombocytes (Platelets)
􏰀 Non-nucleated, oval, colourless 􏰀About 3 μm diameter
􏰀 Important in blood clotting

37
Q

Name the types of blood vessels and their characteristics
How many layers does the heart wall have and name them
What layer forms part of the valves of the heart? What is double circulation ?
How does blood flow in systemic circulation ?
Explain how the heart is supplied with blood

Cardiac muscles
􏰀 have an intrinsic rhythmicity
􏰀 heartbeat originate in and conducted through the heart without extrinsic stimulation.
True or false?
Look at a picture of the parts of the heart

A

Veins
􏰀 Thin-walled, relatively inelastic, valved (low pressure)
􏰀 Carry blood from the tissues or lungs to the heart
􏰀 Smaller veins are called venules. Veins have valves to prevent blood from going backwards. The blood must go only in one direction which is to the heart.
􏰀 Arteries
􏰀 Thick-walled, relatively elastic, no valves (high pressure). It is thick walled because it carries the blood under high pressure away from the heart. It’s high pressure cuz it’s coming from the heart to other parts of the body.
􏰀 Carry blood from the heart to tissues or lungs
􏰀 Smaller veins are called arterioles
􏰀 Capillaries
􏰀 Fine network (meshwork) of vessels bridging arteries and veins
􏰀 Large surface area for exchange of material between blood and tissues
􏰀 Thin-walled

Heart: Wall has 3 layers
􏰀 Epicardium —- outer layer
􏰀 Myocardium —- middle layer.
􏰀 Endocardium — inner layer continuous with the endothelium of
blood vessels. also forms part of the valves of heart.
􏰀 Double circulation: Independent systemic (body) and pulmonary (lung) circulation
􏰀 Systemic (Body) Circulation
OXYGENATED BLOOD → LEFT VENTRICLE → AORTA → BODY

Deoxygenated blood. This blood moves to the vena cava to the right auricle to pulmonary circulation.

RIGHT AURICLE ← VENA CAVA ← DEOXYGENATED BLOOD

Deoxygenated Blood from right auricle moves into pulmonary circulation.

􏰀 Pulmonary (Lung) Circulation
DEOXYGENATED BLOOD → superior(picks deoxygenated blood from head and upper body) and inferior vena cava (picks deoxygenated blood from lower body) → RIGHT VENTRICLE → PULMONARY ARTERY

Lungs to the pulmonary vein to the left auricle.

LEFT AURICLE ← PULMONARY VEIN ← LUNGS

Coronary Circulation
􏰀 Bloodsupplytothetissuesoftheheart
􏰀 Myocardium supplied by the right and left coronary arteries
􏰀 arise from the aorta immediately beyond the aortic semilunar valve.
􏰀 The coronaries encircle the heart within the atrioventricular sulcus,
􏰀 the depression between the atria and ventricles.
􏰀 Two branches arise from both the right and left coronaries to
serve the atrial and ventricular walls.
􏰀 From the capillaries in the myocardium, the blood enters the cardiac veins.
􏰀 The cardiac veins —- coronary sinus —-the right atrium.

38
Q

What is excretion?
What are the ways substances can be excreted?
What is the principal excretory organ?
Where is it located?
Why does the right kidney sit higher than the left one?
Where are the adrenal gland located and what’s their function in excretion?
What is the function of the ureters,bladder and urethra?

A

􏰀Process whereby waste products of body metabolism, and excess substances are removed from the body :
􏰀 Absorption of unneeded substances
􏰀 Absorption of excess nutrients (e.g. proteins, mineral salts,
vitamins, etc.)
􏰀 Osmoregulatory processes (excess water)
􏰀 By-products of cell metabolism (urea, uric acid)

􏰀 Kidneys: Principal excretory organs; purify blood flowing through it 􏰀 They lie against the back of the abdominal wall, outside just above the waistline in the lumbar area. 􏰀 The right kidney sits slightly higher than the left one because of the position of the liver. 􏰀 The adrenal glands (part of the endocrine system) sit on top of the kidneys and release renin which affects blood pressure, and sodium and water retention 􏰀 Ureters – Muscular tubes that transport urine from each kidney to the bladder. 􏰀 Urinary Bladder – A sac that collects and holds urine that comes from the ureters. 􏰀 Urethra – a narrow passageway where urine passes from the bladder to the outside of the body, called urination.
39
Q

The kidneys are divided into three main regions name them
What are the parts of the nephron in order ?
How does urine form through the nephron ?
State three ways urine can form

A

The kidneys are divided into three main regions:
􏰀 renal cortex
􏰀 outer region which contains about 1.25 million renal tubules
􏰀 renal medulla
􏰀 middle region which acts as a collecting chamber
􏰀 renal pelvis
􏰀 inner region which receives urine through the major
calyces
􏰀 Each kidney contains 1.25 million functional units or nephrons (kidney tubules)

􏰀 The nephron has a Malpighian body made up of a glomerulus and Bowman’s capsule, followed in order by the proximal convoluted tubule, loop of Henle, distal convoluted tubule, and collecting duct

Ultrafiltration:
􏰀 Seepage of water/solutes through glomerular blood into Bowman’s capsule
􏰀 Cellular blood elements and high MW substances (e.g. proteins) remain within capillary network
􏰀 Water and low MW substances (mineral salts, glucose, amino acids, urea, etc.) form glomerular filtrate
2.Selective Reabsorption:
Useful solutes (glucose, amino acids, salts) actively transported from proximal
convoluted tubule into surrounding capillaries
3.Secretion
Active secretion of some substances (e.g. urea) directly into the distal convoluted tubule

40
Q

State the constituents of urine
State the layers of the epidermis of the skin and the dermis of the skin and what each layer contains
What are the functions of the skin?

A

CONTITUENTS OF URINE
􏰀 Water (95 %): Osmoregulatory processes/hydrolytic metabolism
􏰀 Urea (carbamide) (2 %):
Deamination of amino acids (liver)
Ornithinecycle(liver)Ammonia,uricacid:
􏰀 Salts (1.4 %) (phosphorus, sulphur (protein metabolism), chlorine,
potassium
􏰀 Creatinine (0.1 %)
􏰀 Urochrome (trace)
􏰀 Cholesterol (excess intake or synthesis)
􏰀 Hormones (excess production- e.g. female pregnancy)

􏰀 Structure  􏰀 Epidermis: Outermost layer 􏰀 Stratum corneum: Cornified layer (dead cells)- protection from damage, infection  􏰀 Stratum granulosum: Middle layer – living cells 􏰀 Stratum germinativum: Pigmented layer (melanin)- actively dividing; keratin

􏰀 Dermis: Inner layer containing vessels, muscles, fat cells, nerves, glands, etc.
􏰀 Hair: Epidermal; dead cells; keratin
􏰀 Erector muscle: Thermoregulation (hair erection/depression)
􏰀 Sebaceous (oil) glands: Sebum (oil) for keeping hair supple (flexible), waterproof
􏰀 Sweat glands: Waste products (e.g. urea, water) for excretion; osmoregulation
􏰀 Eccrine gland
􏰀 Apocrine gland-private part and armpits
􏰀 Nerve endings: Sense of touch, temperature, pressure
􏰀 Adipose tissue: Fat storage (insulation)
􏰀 Scent glands: armpits, back of ears, groin
􏰀 Communication, territoriality, humans dislike own scent

􏰀 Functions
􏰀 Protection from injury, infection, water loss; thermoregulation (insulation, sweating); excretion (sweating); sensory perception (temperature, pressure, pain); Vitamin D synthesis
(from sunlight);
fat storage (food store, insulation)

41
Q

What is the respiratory system
What is the structure of this system?
Why is Alveolar air at atmospheric pressure?
For inspiration,what must happen to alveolar air pressure?
For expiration what must happen to alveolar air pressure?
According to what law do we talk about pressure in the respiratory system?
And what is the application of this law in the respiratory system
What produces surfactant?
Where is surfactant found?
When do the lungs have a tendency to collapse?
How does the surfactant prevent this?

A
Group of cells, tissues and organs that exchanges gases (release of CO2 and uptake of O2) with the environment, and helps distribute those gases within the organism
􏰀 Structure
􏰀 Upper respiratory tract
􏰀 Nostrils/Mouth
􏰀 Nasopharynx/Oral pharynx 
􏰀 Glottis
􏰀 Larynx
Lower respiratory tract:
􏰀 Trachea
􏰀 Bronchi
􏰀 Bronchioles 
􏰀 Alveoli
􏰀 Lungs

Alveolar air is at atmospheric pressure because of direct contact with atmospheric air through trachea, bronchi, etc.
􏰀 For inspiration (drawing air into lungs), alveolar air pressure must be reduced to below atmospheric pressure to create a pressure gradient
􏰀 For expiration (expelling air from the lungs) alveolar air pressure must be increased above atmospheric pressure
􏰀 According to Boyle’s Law (P ∞ 1/V),
􏰀 increase in thoracic volume (relaxation of ribs) results in decreased thoracic
pressure, and inspiration occurs;
􏰀 decrease in thoracic volume (contraction of ribs) results in increased pressure (expiration)

Surfactant is produced in the lungs
􏰀 forms a very thin film which covers the surface of the alveolar
cells
􏰀 During expiration (breathing out)
􏰀 the lungs have a tendency to collapse, if they are allowed to do so then a much greater inspiratory effort is required to open them with the next breath.
􏰀 Surfactant prevents this by reducing surface tension throughout the lung;

42
Q

What are the functions and parts of the skeletal system
Under axial skeleton ,what is dentition ?
What is homodont dentition?
Heterodont dentition ?
Incisors? Canines? Premolars? Diphodont dentition? Milk teeth? Permanent teeth? What is the dental formula? State this formula?(find out more about it)
What is the dental formula for humans,dogs,pigs,cats and sheep

A

SUPPORT
􏰀 Shapes the body
􏰀 Framework (support, particularly on land)
􏰀 Locomotion (movement, with muscular system)
􏰀 Protection for delicate organs (brain, heart, lungs, spinal cord, reproductive organs)
􏰀 Production of red blood cells
􏰀 Mineral storage (e.g. calcium, phosphorus)

􏰀 PARTS-
    Axial Skeleton:
􏰀 Skull/Dentition
􏰀 Vertebral Column
 􏰀 Rib cage
Appendicular Skeleton:
􏰀 Limb Girdles (Pectoral, Pelvic) 
􏰀 Limbs (Fore, Hind)

Dentition: Form, arrangement and number of teeth in a mammal
􏰀 Homodont Dentition: Teeth of same shape and size (e.g. fishes, reptiles)
􏰀 Heterodont Dentition: Teeth of varying shapes/sizes; form relates function 􏰀 Incisors: Sharp chisel-like teeth for cutting and holding/gripping
􏰀 Canines: Larger sharp and pointed teeth for seizing prey/tearing flesh- carnivory
􏰀 Premolars/Molars: Broad, flat grinding teeth (cheek teeth)
􏰀 Diphodont Dentition: Teeth succession at some stage of life. So like in humans, we have this dentition because we have two different sets of teeth at the stages of our life. The primary or milk teeth and then the adult teeth or permanent teeth that come during our entry to adulthood
􏰀 Milk (Deciduous) Teeth: First set of teeth in young mammals
􏰀 Permanent Teeth: Replacement teeth (5-7 years in humans)
􏰀 Dental Formula: Number, types and position of teeth in the mouth

incisor/canine/premolar/molar all divided by
incisor/canine/premolar/molar

Human: 2123 divided by 2123 = 32 
Sheep: 0033 divided by  3133 = 32 
Dog: 3142 divided by 3142 =40 
Pig: 3143  divided by 3143 = 44
Cat: 3131  divided by 3131 =32

The dental formula for a modern human adult is 2:1:2:3 in each quadrant: two incisors, one canine, two premolars, and three molar, for a total of 32 adult teeth.

Because the formula is for one side of the mouth the total number of teeth is the total in the formula x 2. The dental formula for different species are as follows where I = incisors, C = canines, P = premolars and M = molars : Man (adult) I - 2/2 C - 1/1 P - 2/2 M - 3/3 = 16 x 2 = 32.

So it’s like in man 2 incisors on the right,two on the left,one canine on the right and left ,two premolars one the left and two in the right,three molars on left and right for upper teeth
So 16 teeth for the upper teeth and 16 for lower teeth equal to 32 teeth for humans.

43
Q

What is the vertebral column?
Each vertebra comprises of what bones?
What are the types of vertebrae and state the number at each type and the location
Which vertebra is the largest and strongest?
(Look at a pic showing you the vertebrae and it’s parts)
What are the component sof the appendicular skeleton?(look at a pic showing you the parts )
What is the difference between the fore limb and hind limb in the appendicular skeleton

A

Composed of bones called vertebrae, to form a flexible backbone or vertebral column
􏰀 Each vertebra comprises:
􏰀 Centrum – main body
􏰀 Neural canal – contains spinal cord 􏰀 Neural arch
􏰀 Neural spine- backward extension
points downwards
muscle attachment
upwards in animals without erect stance
􏰀 Transverse process
bony protrusion

􏰀 There are five types of vertebrae: 􏰀 Cervical (Neck)- 7, the first two modified into atlas and axis 􏰀 Thoracic (Chest)- 12, with long neural spines and facets for ribs 􏰀 Lumbar (Back)- 5, the largest and strongest vertebrae 􏰀 Sacral (Pelvic)- 5, fused vertebrae forming a T-shaped sacrum 􏰀 Caudal (Tail)- 15, reduced with only 4 remaining (coccyx) in humans
APPENDICULAR SKELETON- LIMB GIRDLES
Pectoral (Upper)
􏰀 Scapula – shoulder blade ..... (furcula, coracoid) 
􏰀 Clavicle – collar bone
􏰀 Sternum
􏰀 Ribs
Pelvic (Lower) 
􏰀 Pubis
􏰀 Ilium
􏰀 Ischium
􏰀 Acetabulum
􏰀 Obturator Foramen 
􏰀 Pubic Symphysis
Fore Limb:
Humerus (Upper arm)
Radius-Ulna (Forearm)
Carpals (Wrist bones)
Metacarpals (Hand bones)
Digits (Fingers)- Pentadactyl
Hind Limb:
Femur (Upper leg)- Thighbone
Patella (Knee cap)
Tibia-Fibula (Foreleg)- Shinbone
Tarsals (Ankle bones)
Metatarsals (Foot bones)
Digits (Toes)- Pentadactyl
44
Q

What is the function of the male reproductive system
Name the parts of this system and state their functions(look at a pic of where they’re all located )
What is the reproductive tract made up of? And state their functions
What are the secondary sexual characteristics in males?
What’s re the accessory reproductive glands
What are seminal vesicles and what’s their function?
Where is prostrate gland located? Where does the urethra run through in relation to the prostate?
Function of the prostrate?
What is prostate cancer and what can be used to treat it?

A

Production of viable spermatozoa (male gametes) by spermatogenesis (sperm production) in seminiferous tubules of the testes (male gonads)
􏰀 Produces many gametes with meager energy reserve
􏰀 Testes: Develop in abdomen, descend into scrotal sac in some mammals
􏰀 Spermatozoa: About 200 million/3 ml of normal healthy human ejaculate (ab. 10 % may be abnormal)
􏰀 Have the following parts:
􏰀 Head (acrosome, nucleus)- enters the egg cell
􏰀 Middle Piece (joined to head by the neck)- contains mitochondria for energy 􏰀 Tail (flagellum/endpiece) – for propulsion
􏰀 Intromittent Organ/Penis: Erectile tissue.
􏰀 Has the following parts: root, body, and glans (covered by prepuce- foreskin) head

Reproductive Tract
􏰀 Epididymis: Long coiled tube for sperm storage/maturation
􏰀 Vas (Ductus) Deferens: Sperm ducts connecting the epididymis to the urethra
􏰀 Urethra: Below bladder, carries both sperm and urine to the outside
􏰀 Secondary Sexual Characteristics: Production of male hormone testosterone at puberty triggers development of 2o sexual characteristics
􏰀 Increased facial/body hair
􏰀 Deepening of voice
􏰀 Greater stature
􏰀 Increased sex drive
􏰀 Interest in the opposite sex

Accessory Reproductive Glands: Prostate, Cowper’s, etc.
􏰀 Correct courtship and mating mechanisms

Seminal vesicles
􏰀 The vasa deferentia (singular: vas deferens) bring sperm from the testes to the
seminal vesicles
􏰀 The seminal vesicles contribute fluid to semen during ejaculation.
􏰀 Prostate gland:
􏰀 Located between the bladder and the penis. The prostate is just in front of the rectum
􏰀 Urethra runs through the center of the prostate, from the bladder to the penis
􏰀 Secretes fluid that nourishes and protects sperm
􏰀 Prostate cancer:
􏰀 It’s the most common form of cancer in men
􏰀 Surgery, radiation, hormone therapy, and chemotherapy can be used to treat prostate cancer.
􏰀 Some men choose to delay treatment, which is called watchful waiting

45
Q

What is the function of the female reproductive system ?
What is oogenesis?
What is the function of the oviduct,uterus,cervix,vagina,vulva,

What triggers development of secondary sexual characteristics for females?
Name some of these characteristics
Name the accessory reproductive glands for females

A

Production of viable ova (female gametes) by oogenesis (ovum production) in ovaries (female gonads)
􏰀 In the process of ova production, females are endowed with only 500 egg cells during embryonic development, and used throughout life
􏰀 well provisioned
􏰀 Oviduct (Fallopian Tube): Analogous to the male vas deferens
􏰀 Uterus (Womb): Thick-walled and muscular for implantation and development of fertilized ovum
􏰀 Cervix: Muscular neck of uterus opening into the vagina
􏰀 Vagina: Connects the uterus to the outside
􏰀 Vulva: Vaginal lip analogous to male scrotum

􏰀 Secondary Sexual Characteristics: Production of female hormones oestrogen, progesterone and luteinizing hormone at puberty triggers development of 2o sexual characteristics (10-14 years in humans)
􏰀 Breast development
􏰀 Underarm and genital hair growth
􏰀 Typical female bone and muscle development pattern (widening pelvis, fat deposition on hips/thighs)
􏰀 Increased sex drive
􏰀 Interest in opposite sex
􏰀 Accessory Reproductive Glands: Preputial, Cowper’s, etc.
􏰀 Correct courtship and mating mechanisms

46
Q

State five differences between eukaryotes and prokaryotes

A

Here are six common differences between eukaryotic and prokaryotic cells:

  1. Cellular Organization:
    • Eukaryotes: Have membrane-bound organelles such as nucleus, mitochondria, endoplasmic reticulum, Golgi apparatus, and lysosomes. These organelles compartmentalize cellular functions.
    • Prokaryotes: Lack membrane-bound organelles. Their cellular processes occur in the cytoplasm, with genetic material (DNA) typically concentrated in a nucleoid region.
  2. Nucleus:
    • Eukaryotes: Possess a membrane-bound nucleus that houses the genetic material (DNA) in the form of linear chromosomes.
    • Prokaryotes: Lack a membrane-bound nucleus. Their genetic material is typically circular and located in the nucleoid region of the cell.
  3. Size and Complexity:
    • Eukaryotes: Generally larger and more complex than prokaryotic cells. Eukaryotic cells range from 10-100 micrometers in size.
    • Prokaryotes: Smaller and simpler in structure. Prokaryotic cells are typically 1-10 micrometers in size.
  4. Reproduction:
    • Eukaryotes: Reproduce by mitosis (asexual reproduction) or meiosis (sexual reproduction). Mitosis involves division of the nucleus, followed by cytokinesis (division of the cytoplasm).
    • Prokaryotes: Reproduce primarily by binary fission, a process where the cell divides into two daughter cells with identical genetic material.
  5. Ribosomes:
    • Eukaryotes: Have larger ribosomes (80S), composed of a 60S and a 40S subunit, involved in protein synthesis within the cytoplasm and on rough endoplasmic reticulum.
    • Prokaryotes: Have smaller ribosomes (70S), composed of a 50S and a 30S subunit, involved in protein synthesis within the cytoplasm.
  6. Membrane Structure:
    • Eukaryotes: Plasma membrane contains sterols (e.g., cholesterol) and is typically more complex. Some eukaryotic cells also have additional membranes, such as the nuclear envelope and membrane-bound organelles.
    • Prokaryotes: Plasma membrane lacks sterols and is simpler in structure. Prokaryotic cells may have additional structures like cell walls (in bacteria) or capsules for protection and adherence.
      Nuclear Envelope**:
    • Eukaryotes: Have a double membrane nuclear envelope that surrounds the nucleus, separating it from the cytoplasm. This envelope contains nuclear pores that regulate the passage of molecules between the nucleus and cytoplasm.
    • Prokaryotes: Lack a nuclear envelope. The genetic material (circular DNA) is located in the nucleoid region within the cytoplasm.
  7. Cytoplasmic Structures:
    • Eukaryotes: Contain cytoskeletal elements such as microtubules, microfilaments, and intermediate filaments that provide structural support and facilitate intracellular transport.
    • Prokaryotes: Generally lack organized cytoskeletal structures, although some species may have proteins that perform cytoskeletal functions.
47
Q

Explain dihybrid and monohybrid crossing

A
  1. Definition: A monohybrid cross involves the study of inheritance patterns for a single trait controlled by one gene.
  2. Example: Consider pea plants with flower color. Let’s use purple (dominant allele, P) and white (recessive allele, p) flowers:
    • Parent 1: PP (purple flowers)
    • Parent 2: pp (white flowers)
    • In this cross, all offspring (F1 generation) will be heterozygous (Pp) and show the dominant purple flower color.
  3. Punnett Square:
    • When you use a Punnett square to predict the offspring, you only consider one gene and its two alleles.
  1. Definition: A dihybrid cross involves the study of inheritance patterns for two different traits controlled by two different genes, located on different chromosomes or far apart on the same chromosome (where crossing over can occur).
  2. Example: Consider pea plants with two traits: seed color (yellow, dominant allele Y vs. green, recessive allele y) and seed shape (round, dominant allele R vs. wrinkled, recessive allele r):
    • Parent 1: YYRR (yellow seeds, round shape)
    • Parent 2: yyrr (green seeds, wrinkled shape)
    • In this cross, the F1 generation will all be heterozygous for both traits (YyRr).
  3. Punnett Square:
    • When using a Punnett square for a dihybrid cross, you consider the inheritance of two genes and their alleles simultaneously. This allows you to predict the possible combinations of alleles and resulting phenotypes in the offspring.
  • Number of Traits: Monohybrid crosses study inheritance patterns for one trait governed by one gene. Dihybrid crosses study inheritance patterns for two different traits governed by two different genes.
  • Allele Combinations: In a monohybrid cross, you examine the combinations of alleles for one gene. In a dihybrid cross, you examine the combinations of alleles for two genes.
  • Punnett Square: A monohybrid cross Punnett square is a 2x2 grid (for two alleles), while a dihybrid cross Punnett square is a 4x4 grid (for four allele combinations).

In summary, the main difference between a monohybrid and a dihybrid in genetics is the number of traits and genes being studied. Monohybrid crosses focus on one trait governed by one gene, whereas dihybrid crosses focus on two different traits governed by two different genes.

48
Q

Explain back cross and test cross

A

􏰀Backcross- crossingofahybridwithoneofitsparents

Purpose of Backcrossing:
Backcrossing is performed primarily to transfer or reinforce a desirable trait or allele from one parent (usually the donor parent) into the genetic makeup of another parent (usually the recurrent parent). The recurrent parent typically possesses the desired overall genetic background or other favorable traits, while the donor parent carries the specific trait of interest that is to be introduced or reinforced
So example is let’s say you have a parent plant that is pink and keeps producing pink plants but from its original parents plant, the plant is supposed to be pink with white spots. Since you want the new plants to have the original makeup which is pink with white spots, you cross the current parent plant that is only pink and gives birth to pink plants with the original plant that has pink with white spots so that now, the pink only plant will give birth to pink and white spots plants. This keeps this trait instead of it dying out.
􏰀 Test cross: a genetic cross between a homozygous recessive individual and a corresponding suspected heterozygote to determine the genotype of the latter. A test cross is a genetic cross used to determine the genotype of an individual showing a dominant phenotype. Here’s a simple explanation:

  • Purpose: To find out if an organism with a dominant phenotype (expressing the dominant trait) is homozygous dominant (two dominant alleles) or heterozygous (one dominant and one recessive allele). Exmaple, you see a person who is Tall (phenotype) and you want to find out if his tall is Tt (heterozygous genotype) or TT(homozygous genotype )
  • Procedure: The organism with the dominant phenotype is crossed with an organism that is homozygous recessive (has two recessive alleles for the trait).
  • Example: Let’s use flower color in pea plants:
    • Parent 1: Unknown genotype with purple flowers (PP or Pp).
    • Parent 2: Homozygous recessive with white flowers (pp).
  • Outcome:
    • If all offspring have purple flowers, the unknown parent is homozygous dominant (PP).
    • If some offspring have white flowers, the unknown parent is heterozygous (Pp).
  • Significance: A test cross helps determine whether the dominant phenotype is due to homozygous dominant or heterozygous genotype. It’s a tool to understand genetic inheritance patterns and predict the likelihood of passing on traits to offspring.
49
Q

In which of the
following instances or scenarios is active transport not at play?
Select one
A. Endocytosis
B. Sodium
Potassium Pump
C. Glucose transporter
D. Electron transport chain

A

Active transport is not at play in the scenario of Endocytosis.

Endocytosis is a process by which cells engulf external substances by forming vesicles around them and bringing them into the cell. This process does not directly involve the expenditure of cellular energy (ATP) to actively transport molecules against a concentration gradient, which is a characteristic feature of active transport mechanisms like the Sodium-Potassium Pump and Glucose Transporters.

In contrast:
- The Sodium-Potassium Pump actively transports sodium ions out of the cell and potassium ions into the cell against their concentration gradients, requiring ATP.
- Glucose Transporters facilitate the movement of glucose across cell membranes, but some types (like GLUT transporters) do so by facilitated diffusion (passive transport), while others (like SGLT transporters) use active transport.
- The Electron Transport Chain is involved in oxidative phosphorylation in mitochondria, producing ATP through the transfer of electrons, which indirectly supports active transport processes in cells.

Therefore, among the options provided, Endocytosis does not involve active transport.

50
Q

Cells with high mitochondria have increased metabolism and glucose/fructose expenditure. Which of the following cells exhibit the above in an unusual faction?
• Select one
Red Blood Cells
Sperm Cells
C. Hepatocytes
D. Myocytes

A

Among the options provided, Red Blood Cells (RBCs) exhibit an unusual faction compared to the others listed.

Red Blood Cells lack mitochondria and rely solely on anaerobic glycolysis for their energy needs. This means they do not undergo oxidative metabolism or use glucose/fructose in the typical mitochondrial-dependent manner seen in cells with high mitochondria content. Therefore, RBCs do not exhibit the increased metabolism and glucose/fructose expenditure associated with mitochondrial-rich cells like hepatocytes, myocytes, or even sperm cells, which utilize mitochondria for energy production.

51
Q

Homologous chromosome explained
Note that this is different from homozygous and heterozygous alleles

A

Homologous chromosomes are pairs of chromosomes in a diploid organism that have the same genes at the same loci, but may have different alleles. Each pair consists of one chromosome inherited from the mother and one from the father. Here is an example:

In humans, we have 23 pairs of homologous chromosomes, making a total of 46 chromosomes.

  • Chromosome Pair 1: The first pair of homologous chromosomes. One chromosome in this pair is inherited from the mother, and the other is inherited from the father. Both chromosomes carry genes that determine the same traits, such as those involved in growth and development, but they may carry different alleles for those genes.

For instance, at a specific locus on Chromosome Pair 1:
- The maternal chromosome might carry an allele for brown eyes (B).
- The paternal chromosome might carry an allele for blue eyes (b).

Thus, this pair of chromosomes is homologous because they have the same genes in the same order, but they might have different versions (alleles) of those genes.

  • Chromosome Pair 2: Another pair of homologous chromosomes, and the same principle applies. If you consider a gene that affects hair type:
    • The maternal chromosome might have an allele for curly hair (C).
    • The paternal chromosome might have an allele for straight hair (c).

Again, these are homologous because they contain the same genes but can have different alleles.

Every pair of chromosomes in a diploid organism is homologous, and this structure is essential for the processes of meiosis and sexual reproduction, ensuring genetic diversity.

Yes, homologous chromosomes have the same genes in the same order along their length. Here’s a more detailed explanation:

  • Homologous Chromosomes: These are pairs of chromosomes in a diploid organism where one chromosome comes from the mother (maternal chromosome) and the other from the father (paternal chromosome). They have the same length, the same centromere position, and the same staining pattern when dyed.
  • Same Genes: Both chromosomes in a homologous pair contain the same genes at the same loci (specific locations on the chromosome). For example, if there is a gene for eye color at a particular locus on one chromosome, the other chromosome in the homologous pair will also have a gene for eye color at the same locus.
  • Same Order: The genes are arranged in the same sequence on both chromosomes. This ensures that during meiosis, when chromosomes pair up and exchange segments (crossing over), the genes are aligned correctly.

For example:
- If a gene for hair color is located at position 5 on the maternal chromosome 1, the paternal chromosome 1 will also have a gene for hair color at position 5.
- Similarly, if a gene for blood type is at position 20 on both maternal and paternal chromosome 1, they will both have a gene for blood type at that same position.

However, the specific versions of the genes (alleles) can differ. For instance, the gene for eye color on the maternal chromosome might be the allele for brown eyes (B), while the same gene on the paternal chromosome might be the allele for blue eyes (b). This variation in alleles is what contributes to genetic diversity.

The definition of an allele actually pertains to homologous chromosomes, not homozygous chromosomes. Here’s the key distinction:

  • Alleles: Different forms or varieties of a gene that occupy the same locus on homologous chromosomes. Homologous chromosomes are pairs of chromosomes (one from each parent) that have the same genes at the same loci, but possibly different alleles.
  • Homozygous: Refers to having two identical alleles at a particular gene locus on both homologous chromosomes.
  • Heterozygous: Refers to having two different alleles at a particular gene locus on the homologous chromosomes.

The definition of an allele emphasizes homologous chromosomes because alleles are versions of the same gene found at the same location on each of a pair of homologous chromosomes. These chromosomes can carry either the same allele (homozygous) or different alleles (heterozygous).

To restate:

  • Homologous chromosomes: Pairs of chromosomes with the same genes at the same loci.
  • Homozygous: Having identical alleles at a specific locus on both homologous chromosomes.
  • Heterozygous: Having different alleles at a specific locus on both homologous chromosomes.

The definition you mentioned is focused on the idea that alleles are versions of the same gene located at the same position on homologous chromosomes, which is foundational to understanding genetic variation.