Biological Sciences 24 Flashcards

1
Q

pre ganglionic fibers of the sympathetic nervous system are associated where

A

paravertebral chain ganglia

synaptic trunk

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2
Q

what attaches the chain ganglia to the spinal nerves

A

grey and white rami

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3
Q

which type of fiber passes thru the white rami

A

preganglionic sympathetic neuron

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4
Q

which sympathetic fiber is myelinated ?

A

preganglionic are myelinated

postganglionic are unmyelinated

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5
Q

Which rami do post ganglionic sympathetic fibers?

A

gray rami

allows them to reenter spinal nerves to go to skin

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6
Q

what does post ganglionic sympathetic fibers control?

A

blood vessels
sweat glands
piloerector muscles

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7
Q

splanchnic nerves

A

composed of pre-ganglionic fibers and visceral sensory fibers

myelinated

supply abdominal viscera

synapse in pre vertebral ganglia

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8
Q

where do splanchnic nerves synapse

A

pre vertebral ganglia

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9
Q

greater splanchnic nerves

spinal nerves
synapse:

A

T5-T9

synapses in celiac ganglion

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10
Q

lesser splanchnic nerves

spinal nerves
synapse:

A

T10-T11

synapses in superior mesenteric ganglion

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11
Q

Least splanchnic nerves

spinal nerves
synapse:

A

T12

synapses in aorticorenal ganglion

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12
Q

which nerve carries most of parasympathetic fibers?

A

vagus n.

CN 10

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13
Q

where to parasympathetic preganglionic fibers synapse?

A

at the organ to be innervated

often ganglia are found in walls of organ

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14
Q

post ganglionic parasympathtetic fibers

A

are located on wall of organ

use Ach as neurotransmitter

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15
Q

what are the main nerves that supply parasympathetics to the body

A

Oculomotor
Facial
Vagus
Glossopharyngeal

(III, VII, IX, X)

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16
Q

functions of oculomotor nerves

A

supplies 4 of 6 extrinsic muscles of eye and levator palpebral superioris

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17
Q

preganglionics of oculomotor n.

A

from edinger westphal nucleus to ciliary ganglion

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18
Q

post ganglionic of oculomotor n.

A

from ciliary ganglion to sphincter pupillae muscle

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19
Q

Functions of facial n.

A

muscles of facial expression

taste to anterior 2/3 of tongue

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20
Q

preganglionics of facial n.

A

from superior salivary and lacrimal nuclei to submandibular/sublingual ganglia

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21
Q

postganglionic of facial n.

A

to lacrimal gland, submandibular gland, sublingual gland, mucous glands of mouth and nose

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22
Q

glossopharyngeal n. function

A

carries general sensation

sensation of taste from posterior 1/3 of tongue of tongue

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23
Q

preganglionic of glossopharyngeal n.

A

from inferior salivary nucleus to otic ganglion

24
Q

postganglionic of glossopharyngeal

A

post ganglionics to parotid gland

25
vagus n. function
motor supply to muscles of 4 and 6 pharyngeal arches important in swallowing, speaking
26
which n. is the major parasympathetic supply to thoracic and abdominal organs
vagus n.
27
preganglionics of vagus n.
from dorsal motor nucleus
28
postganglionics of vagus n.
from dorsal motor nucleus
29
post ganglionic of vagus n.
myenteric plexus of wall of gut tube @ left colic flexure
30
Course of the vagus n.
runs parallel to esophagus (innervates it) passes posterior to root of lung (both sides) pierces diaphragm with esophagus becomes gastric n. supplies viscera in thoracic cavity
31
norepinephrine synthesis
hydroxylation of tyrosine dopa
32
epinephrine
norepinephrine is methylated to form epinephrine
33
neurotransmitters of parasympathetic
epinephrine norepinephrine acetylcholine
34
mechanisms of removal of norepinephrine
reuptake diffusion destruction by monamine oxidase destruction by COMT
35
monamine oxidase
found in nerve endings destroys norephineprine
36
COMT
breaks down norepinephrine in the blood
37
muscarinic receptors
found on all effector cells stimulated by postganglionic cholinergic neurons
38
nicotinic receptors
autonomic ganglia at synapses between preganglioniic and post ganglionic neurons present in neuromuscular junctions in skeletal muscles
39
types of adrenergic receptors
``` alpha 1 alpha 2 beta 1 beta 2 beta 3 ```
40
what type of receptors does epinephrine exited
both alpha and beta
41
norepinephrine/epinephrin is active for ____ when secreted into tissues but when secreted into blood it is active ____
few seconds in tissue in blood it stays until destroyed by COMT
42
types of acetylcholine receptors
muscarinic nicotinic (cholinergic receptors)
43
what type of receptors are activated by norepinephrine
alpha receptors
44
beta3
thermogenesis
45
sympathomimetic drugs
``` norepinephrine epinephrine methoxamine phenylephrine (alpha r.) isoproterenol (beta r.) albuterol (beta 2 r. ) ```
46
drugs that cause the release of norepinephrine
ephedrine tyramine amphetamine
47
drugs that block adrenergic activity
* Reserpine * Guanethidine * Phenoxybenzamine/phentolamine * Propranolol * Metoprolol * Hexamethonium
48
• Reserpine
• Blocks synthesis and storage of norepinephrine
49
• Guanethidine
• Blocks release of norepinephrine
50
• Phenoxybenzamine/phentolamine
• Block sympathetic alpha receptors
51
• Propranolol
• Blocks sympathetic beta1 and beta2 receptors
52
• Metoprolol
• Blocks mostly sympathetic beta1 receptors
53
Hexamethonium
• Blocks transmission through autonomic ganglia
54
Parasympathomimetic drugs
* Not rapidly destroyed by cholinesterase * Include pilocarpine and methacholine * Act directly on muscarinic receptors *cholinergic effector organs*
55
Drugs that inhibit acetylcholinesterase:
* Neostigmine * Pyridostigmine * Ambenonium
56
Drugs that block cholinergic activity
* Atropine * Homatropine * Scopolamine