biological molecules Flashcards

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1
Q

What are the four biological molecules and what elements do they contain?

A

Carbohydrates: C, H and O
Lipids: C, H,O
Proteins: C, H , N, O , S
Nucleic acids: C, H, O, N, P

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2
Q

Why is water polar?

A

Water contains O-H bonds where the electrons are unequally shared creating separate regions of positivity and negativity,

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3
Q

What are the key characteristic of water and why does it have these characterisitics?

A
  • Water has a relatively high BP as it has h-bonding which requires a lot of energy for H2O to evaporate
  • Water is more dense in a solid state (as ice) as the h-bonds will position the polar molecules slightly further apart creating an open structure that is less dense than liquid.
  • Water has cohesive and adhesive properties as it can form h-bonds with other water molecules and other materials
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4
Q

How do the key characteristics of water help life?

A
  • Acts as a solvent where many solutes can dissolve , acting as a medium for chemical reactions and transporting dissolved compounds.
  • Acts as a transport medium with the action of cohesion and adhesion it exhibits capillary action such as water travelling up the xylem.
  • Acts as a coolant to buffer temperature changes and maintaining constant temperature in environments
  • Water is stable and will not change temperature making a good environment for aquatic creatures to live in. Dense ice can act as an insulating layer
  • Surface tension due to cohesive properties act as a habitat for small creatures like pond skaters
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5
Q

What is a monosaccharide, disaccharide and polysaccharide? Give examples.

A

MS: a single sugar unit/monomer such as glucose, fructose and ribose
DS: When two MS link together, for example lactose and sucrose
PS: A polymer made up of MS such as glycogen, cellulose and starch

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6
Q

What is the structure of glucose and what is the difference between a beta and alpha glucose?

A

Glucose is a hexose monosaccharide with 6 carbons with chemical formulae C6H12O6

a-glucose has a hydrogen above the OH on the first and second carbon
b-glucose will have a OH group above the H on the first carbon

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7
Q

What is a glycosidic bond? What types of glycosidic bonds are there?

A

A glycosidic bond is formed between two glucose molecules via a condensation reaction where the two OH- groups will react.

Straight chained molecules will have 1,4 glycosidic bonds whereas branched will have 1,4 and 1,6 glycosidic bonds.

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8
Q

What is starch, what polysaccharides are in starch and what are their structures? Why do they have these structures?

A

Starch is a chemical energy store found in plants made up of amylopectin and amylose.

Amylose: Made up of alpha glucose joined together via 1-4 glycosidic bonds and twists to form a helix. This makes it more compact and less soluble.
Amylopectin: Is branched so it has both types of glycosidic bonds making it more accessible to be broken off by enzymes and converted to glucose for energy use.

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9
Q

What is glycogen, its structure and purpose?

A

Glycogen is the energy store equivalent of starch found in animals and fungi which is more branched than amylopectin making it compact, ideal for storage. Branched = more accessible and insoluble.

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10
Q

What is a hydrolysis reaction?

A

Hydrolysis reactions are the addition of H2O molecules which reverse the effect of condensation reactions.

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11
Q

What is a triglyceride?

A

A lipid that consists of a glycerol molecule connected to three fatty acid tails.

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12
Q

How does glycerol form a bond with fatty acids?

A

Via esterification when the two -OH bonds interact and form an ester bond.
This is a condensation reaction

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13
Q

What is the difference between a saturated and an unsaturated fatty acid?

A

Saturated: Presence of no double c=c bonds , they do not kink and are solid fats which are more unhealthy.
Unsaturated: Presence of double c=c bonds, they kink and occur as oils which are more healthy in the human diet

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14
Q

What are phospholipids?

A

Similar to triglycerides but one of the fatty acids are replaced by a phosphate group.
They have hydrophobic tails but hydrophilic heads .
They can create a bilayer arrangement important in the formation of cell membranes.

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15
Q

What are sterols and what is cholestral?

A

Sterols are complex alcoholic molecules that are a type of lipid which also have dual hydrophilic and hydrophobic traits.
Choestral is a sterol which are positioned in-between phospholipids by adding stability to membranes and regulating their fluidity.

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16
Q

What are the roles of lipids?

A
  • Membrane formation
  • Electrical insulation
  • Water proofing
  • Thermal insulation
  • Cushioning of organs
  • Buoyancy
17
Q

How can you test for lipids?

A

Lipids can be tested for via an emulsion test where you mix a sample with ethanol and if there is a lipid present , a white milky emulsion will form.

18
Q

What are proteins made out of?

A

Proteins are made out of polypeptides formed from amino acids.

19
Q

How are peptides synthesised?

A

Peptides are synthesised via a peptide bond formed between an anime group and the OH- of a carboxylic acid which is another condensation reaction

20
Q

What are the levels of protein structure?

A

Primary: The sequence of amino acids which influence the way a polypeptide will fold

Secondary: The structures of amino acids will react, hydrogen bonds will form within forming an alpha helix or a beta pleated sheet when parallel to each other.

Tertiary: The folding of a protein into a 3D shape due the interactions between the R-groups which will form different types of bonds, for example disulphide bridges, hydrophobic and hydrophilic interactions, hydrogen bonds and ionic bonds.

Quarternary: Association between two or more proteins called subunits

21
Q

How do you identify a protein?

A

You identify a protein via a biuret test which will produce a blue/purple colour

22
Q

What is a globular protein and what is a fibrous protein?

A

A globular protein is a compact , water soluble and spherical protein where the hydrophobic r-groups are away from the environment.

A fibrous protein is a long, insoluble molecule with a repetitive structure to produce a strong build.

23
Q

What is a conjugated protein?

A

Globular proteins which contain a non-protein component called a prosthetic group

24
Q

What is collagen?

A

Collagen is a fibrous protein found as connective tissue made up of three polypeptides wound together in a long rope-like structure.

25
Q

What are nucleic acids?

A

Nucleic acids are large polymers made from nucelotides, for example DNA and RNA.

26
Q

What is the structure of a nucleic acid?

A
  • A pentose monosaccharide
  • a phosphate group
  • a nitrogenous base
27
Q

How do nucleotides link together?

A

Nucleotides link together by condensation reactions between a hydroxyl group on the pentose sugar and a phosphate group which forms a phosphodiester bond

28
Q

What is the difference between a pyrimidine and a purine?

A

Pyrimidine: Thymine, cytosine, uracil which are larger , two ringed bases.
Purines: Adenine and guanine, which are smaller single ringed bases

29
Q

What is complimentary base pairing?

A

Adenine and thymine, or adenine and uracil can form two bonds and will always bond with each other whereas cytosine and guanine will always form three hydrogen bonds with each other.

Complimentary base pairing means that there will always be equal amounts of pyrimidine and its matching purine.