"biological explanations for SZ: Neural correlates and the dopamine hypothesis" Flashcards

1
Q

The Neural correlates explanation states that what things may be linked with the development of SZ

A

Abnormalities in the Brain

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2
Q

brain scan techniques such as what are used to study the idea of Neural correlates

A

FMRI scans

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3
Q

when using FMRI scans to study brain activity, who’s brains are compared

A

Neuro-typical brains and SZ sufferers brains

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4
Q

when using FMRI scans, why do we compared the brains of a SZic with a Neurotypical

A

to identify regions linked to SZ

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5
Q

which part of the brain has been shown to be enlarged in sufferers of SZ

A

Ventricles

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6
Q

who conducted a meta-analysis that supported the idea that SZ sufferers had enlarged ventricles when compared to a control group

A

Raz and Raz

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7
Q

in Raz and Raz’s study, what % of the schizophrenics had increased ventricle size in comparison to the control group

A

over 50%

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8
Q

in SZ, enlarged ventricles are associated with damage to which area of the brain

A

Pre-Frontal Cortex

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9
Q

brain damage to the Pre-Frontal cortex has been associated with which types of symptoms in SZ

A

Negative Symptoms

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10
Q

what is a negative symptom of SZ that is associated with damage to the Pre-Frontal Cortex

A

Avolition (poor Motivation)

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11
Q

who conducted research to support the role of Neural correlates to explain SZ

A

Suddath Et Al

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12
Q

what technique did Suddath et al use to investigate brain structure

A

MRI scans

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13
Q

in Suddath et al’s research, who was the sample

A

A pair of Monozygotic twins

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14
Q

in Suddath et Al’s research,what did one of the twins suffer with

A

Schizophrenia

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15
Q

what was the finding of Suddath et Al’s research into neural correlates

A

the SZ twin had larger ventricles compared to the non-SZ twin

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16
Q

Suddath et Al’s research suggests that which brain abnormality DOES play a role in developing SZ

A

Enlarged Ventricles

17
Q

Suddath et Al’s research also increases which aspect of the neural correlate argument

A

the Validity

18
Q

the Dopamine Hypothesis states that WHAT in the brain appear to work differently in people with SZ

A

Neurotransmitters

19
Q

which neurotransmitter in particular is said to be highly involved in SZ

A

Dopamine (DA)

20
Q

Individuals with SZ may suffer from which 2 conditions in relation to DA?

A

Hyperdopaminergia and Hypodopaminergia

21
Q

People suffering with SZ may also have too many WHAT

A

D2 Receptors

22
Q

in SZ, where are D2 receptors located

A

Post-Synaptic Neuron

23
Q

In which location of the brain is Hyperdopaminergia seen in SZ

A

the Sub Cortex

24
Q

Hyperdopaminergia refers to when an individual has what level of dopamine activity

A

High Level of Dopamine activity

25
Q

in which specific region of brain do sufferers of SZ have high dopamine activity

A

Broca’s area

26
Q

what is Broca’s area said to be responsible for

A

Speech Production

27
Q

High dopamine activity in Broca’s area has thus been associated with which specific positive symptom of SZ

A

Auditory Hallucinations

28
Q
A