"biological explanations for SZ: Neural correlates and the dopamine hypothesis" Flashcards

1
Q

The Neural correlates explanation states that what things may be linked with the development of SZ

A

Abnormalities in the Brain

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2
Q

brain scan techniques such as what are used to study the idea of Neural correlates

A

FMRI scans

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3
Q

when using FMRI scans to study brain activity, who’s brains are compared

A

Neuro-typical brains and SZ sufferers brains

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4
Q

when using FMRI scans, why do we compared the brains of a SZic with a Neurotypical

A

to identify regions linked to SZ

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5
Q

which part of the brain has been shown to be enlarged in sufferers of SZ

A

Ventricles

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6
Q

who conducted a meta-analysis that supported the idea that SZ sufferers had enlarged ventricles when compared to a control group

A

Raz and Raz

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7
Q

in Raz and Raz’s study, what % of the schizophrenics had increased ventricle size in comparison to the control group

A

over 50%

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8
Q

in SZ, enlarged ventricles are associated with damage to which area of the brain

A

Pre-Frontal Cortex

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9
Q

brain damage to the Pre-Frontal cortex has been associated with which types of symptoms in SZ

A

Negative Symptoms

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10
Q

what is a negative symptom of SZ that is associated with damage to the Pre-Frontal Cortex

A

Avolition (poor Motivation)

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11
Q

who conducted research to support the role of Neural correlates to explain SZ

A

Suddath Et Al

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12
Q

what technique did Suddath et al use to investigate brain structure

A

MRI scans

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13
Q

in Suddath et al’s research, who was the sample

A

A pair of Monozygotic twins

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14
Q

in Suddath et Al’s research,what did one of the twins suffer with

A

Schizophrenia

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15
Q

what was the finding of Suddath et Al’s research into neural correlates

A

the SZ twin had larger ventricles compared to the non-SZ twin

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16
Q

Suddath et Al’s research suggests that which brain abnormality DOES play a role in developing SZ

A

Enlarged Ventricles

17
Q

Suddath et Al’s research also increases which aspect of the neural correlate argument

A

the Validity

18
Q

the Dopamine Hypothesis states that WHAT in the brain appear to work differently in people with SZ

A

Neurotransmitters

19
Q

which neurotransmitter in particular is said to be highly involved in SZ

A

Dopamine (DA)

20
Q

Individuals with SZ may suffer from which 2 conditions in relation to DA?

A

Hyperdopaminergia and Hypodopaminergia

21
Q

People suffering with SZ may also have too many WHAT

A

D2 Receptors

22
Q

in SZ, where are D2 receptors located

A

Post-Synaptic Neuron

23
Q

In which location of the brain is Hyperdopaminergia seen in SZ

A

the Sub Cortex

24
Q

Hyperdopaminergia refers to when an individual has what level of dopamine activity

A

High Level of Dopamine activity

25
in which specific region of brain do sufferers of SZ have high dopamine activity
Broca's area
26
what is Broca's area said to be responsible for
Speech Production
27
High dopamine activity in Broca's area has thus been associated with which specific positive symptom of SZ
Auditory Hallucinations
28