Biological explanations: dopamine hypothesis Flashcards
what is dopamine ?
- a neurotransmitter
- that induces the feeling of pleasure
- and is involved in reinforcing particular behaviour as part of a reward pathway
what does the dopamine hypothesis suggest?
- suggests that excessive amounts of dopamine in certain regions of the brain (sub cortex) are associated with positive symptoms
what area of the brain may be responsible for auditory hallucinations (positive symptom) ?
- excess of dopamine in the broca’s area
what area of the brain may be responsible for negative symptoms ?
- low levels of dopamine
- in prefrontal cortex
what is meant by an agonist drug ?
- a drug that increases dopaminergic activity
what are the 2 agonists drugs ?
- amphetamine
- L-dopa
what does amphetamine do ?
- stimulates nerve cells containing dopamine
what do people who take amphetamine recreationally experience ?
- may experience symptoms of schizophrenia
- positive symptoms
what is parkinson’s disease characterised by ?
low levels of dopamine
what is parkinson’s disease treated with ?
- L-dopa
what can taking L-dopa lead to ?
- it can lead to the development of schizophrenia symptoms
what is meant by antagonist drugs ?
- drugs that decrease dopaminergic activity
what is an example of an antagonist drug to alleviate symptoms of schizophrenia ?
- anti-psychotic drugs
what do anti-psychotic drugs do to the body ?
- they block activity of dopamine
- and so alleviate many of the symptoms of schizophrenia like hallucinations and delusions