Biological Flashcards

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1
Q

Outline the initiation of smoking via the reward system (biological addiction)

A
  • reward system activated when smoking
  • NAChRs triggered
  • Nicotine binds to NAChRs
  • dopamine released
  • memory created, making the individual crave the affect of dopamine
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2
Q

Outline the initiation of smoking via genes (biological addiction)

A
  • gene influence the use of tobacco by 39-80%
  • Commings et al (1996) = A1 variation in the DRD2 gene. Smokers = 48% likely to have this gene, non-smoker = 25%
  • Nobel et al (2000) = the A1 variation of the DRD2 gene is the reward gene - fewer dopamine receptors (lacks pleasurable experiences)
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3
Q

Outline the maintenance of smoking (biological addiction)

A

Chronic exposure leads to a reduction of activity in the reward pathway (down regulation). The more it’s taken, the less the affect on dopamine. Taken to avoid discomfort

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4
Q

Outline the relapse of smoking (biological addiction)

A

Pre-frontal cortex becomes less affected in chronic drug users, especially with decision making and judgement. Xian found genetic factors accounted for 54% of quitting failures

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5
Q

Outline initiation of gambling (biological addiction)

A
  • Shah (2005) = gambolling transmitted genetically in males

* Black (2006) = first degree relatives were more likely to inherit the gene

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6
Q

Outline the maintenance of gambling (biological addiction)

A
  • Zuckerman (1979) = individual differences, sensation seeking theory
  • Bonnaire et al (2007) = chronic gamblers scored higher on sensation seeking questionnaires
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7
Q

Outline relapse of gambling (biological addiction)

A

Rosenthal and Lesieur (1992) found gamblers seek the thrill, boredom avoidance

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8
Q

Evaluation points of the biological model? (Biological addiction)

A
  • diathesis stress model
  • stigmatisation
  • use of family studies
  • cause and effect between smoking and PFC
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9
Q

What is addiction? (Biological addiction)

A

A state that may occur when consuming substances or participation in an activity that leads to excessive use disrupting everyday functioning

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