Biol Lab Exam Quiz 1 Flashcards
Population
All organisms of the same group or species that inhabit the same area and can interbreed
What are the assumption of HWE?
No Selection
No Gene flow
Random mating
Infinite population size
No mutation
HW Equation
p^2 + 2pq + q^2
allelic frequency
how often an allele shows up in a population
Genotypic frequency
how common a single phenotype occurs in a population
Describe how you would expect the allelic and genotypic frequencies of a population to change when subjected to each of the five evolutionary processes (Genetic drift)
frequencies will change randomly - if the population is small enough, it may lead to the fixation of one of the alleles.
We discussed two methods for deleterious alleles to persist in a population. What were these? Which applied to Sickle Cell Anemia ?
-Heterozygote Advantage (This applied to SCA!)
-Recessive Refuge
Heterozygote advantage
when the heterozygous genotype has an advantage over either of the homozygous genotypes
examples: being heterozygous with an allele for sickle cell trait and an allele for normal red blood cells.
gel electrophoresis lane 1
positive control
In terms of the malaria experiment: HbS-HbS genotypic blood (sickle cell)
gel electrophoresis lane 2
negative control
in terms of the malaria experiment: HbA-HbA genotypic blood (no sickle cell) (will be further down compared to the sickle cell control)
What does it mean if the hemoglobin travels farther?
Normal hemoglobin travels faster than those with sickle cell anemia because of its shape. So further travel means normal hemoglobin.
Recessive Refuge
phenomenon that enables a deleterious recessive allele to persist in a gene pool by “hiding out” in heterozygous individuals
Apomorphy
new, derived characteristic unique to a group or species. (not present in ancestor)
plesiomorphy
ancestral trait a taxon retains throughout its evolution.
synapomorphic traits
shared derived traits present in entire clade
autapomorphic traits
unique, derived traits found in only one group and absent in even the closest ones
symplesiomorphic traits
shared, ancestral trait (shared by two taxa and still have the ancestral trait)
sister taxa
two taxa that share the most recent common ancestor
Node
branch point that represents a taxonomic level