Biochem - nutrition Flashcards

1
Q

Vitamins stored in the liver

A

Folate and B12

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2
Q

Night blindness, dry/scaly skin, corneal degradation

A

Vit. A deficiency

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3
Q

Used to treat measles and AML subtype M3

A

Vitamin A

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4
Q

impaired glucose breakdown affects highly aerobic tissues first (brain, heart)

A

Thiamine (B1) deficiency

used in alpha-keotglutarate dehydrogenase, transketolase, pyruvate dehydrogenase

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5
Q

Cheliosis (inflammation of lips, scaling of ends of mouth), corneal vascularization

A

Riboflavin (B2) deficiency

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6
Q

Used as cofactor in redox reactions

A

Riboflavin is a component of FAD and FMN

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7
Q

Glossitis, pellagra (dermatitis, dementia, diarrhea)

A

Niacin (B3) deficiency

constituent of NAD/NADP

lowers levels of VLDL and raises HDL (take aspirin to prevent flushing)

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8
Q

Component of coenzymeA (CoA) and fatty acid synthase

A

Pantothenic acid (B5)

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9
Q

Consulsions, peripheral neuropathy, sideroblastic anemia (decr. Hgb synth/iron excess)

A

Pyridoxine (B6) deficiency

used in synthesis of neurotransmitters, heme, niacin, histamine, cystathione

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10
Q

Vitamin deficiency caused by excessive ingestion of eggs or antibiotic use

A

Biotin (B7)

Caused by avidin

used as a cofactor in carboxylation reactions

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11
Q

Megaloblastic anemia w/o neuro symptoms, incr. homocysteine w/ normal MMA levels

A

Folate (B9) deficiency

seen in alcoholism/pregnancy

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12
Q

Megaloblastic anemia w/ neuro symptoms (parasthesias, subacute combined degeneration), incr. homocysteine and incr. MMA levels

A

Cobalamin (B12) deficiency

seen in alcoholism

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13
Q

Corkscrew hair, swellen gums, bruising, petechiae

A

Vit. C deficiency

decr. hydroxylation of proline and lysine in collagen synthesis (rough ER)

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14
Q

Hemolytic anemia, acantholysis, muscle weakness, posterior column/ST tract demyelination

A

Vitamin E deficiency

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15
Q

Delayed wound healing, hypogonadism, decr. adult hair

A

Zinc deficiency

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