biochem exam 2-Vitamin Flashcards

1
Q

how many B vitamins we need to know?

A

8

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2
Q

is vitamin B water soluble?

A

yes

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3
Q

B1

A

thiamin
part of thiamine pyrophosphate (TPP)
coenzyme in PDH complex in conversion of pyruvate to acetyl-coA

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4
Q

Deficiencies of B1

A

beriberi, wernicke-korsakoff syndrome

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5
Q

B2

A

riboflavin

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6
Q

deficiencies of B2

A

cheilosis, glossitis

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7
Q

B3

A

Niacin

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8
Q

B3-niacin: coenzymes forms are

A

NAD, NADP

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9
Q

B3 deficiencies

A

pellagra

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10
Q

B5

A

pantothenic acid

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11
Q

B6

A

pyridoxine/pyridoxal/pyridoxamine

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12
Q

importance of B6

A

important for catecholamine synthesis - amino acid metabolism

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13
Q

T/F PLP- pyridoxine only water soluble vitamin with significant toxicity.

A

True

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14
Q

deficiencies of B6

A

scaly dermatitis, anemia

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15
Q

B7

A

biotin

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16
Q

B7 (biotin)- used in __________ reactions for FA synthesis

A

carboxylation

17
Q

B9

A

Folic acid

18
Q

B9 (folic acid)- tetrahydrofolate (THF). Important for

A

pregnant women

19
Q

B9 deficiencies

A

Anemia, Spina bifida, anencephaly

20
Q

B12

A

Cobalamin

21
Q

B12: new cell synthesis. Binds to ______.

A

intrinsic factor.

22
Q

what is the deficiencies of B12

A

pernicious anemia

23
Q

Mnemonic for vitamin order

A

Tyler Really Needs Paper Possibly Buying Fresh Cocaine

24
Q

Vitamin C

A

ascorbic acid

25
Q

function of vitamin C

A

collagen synthesis and good for hydroxylation

26
Q

deficiency of vitamin C

A

scurvy

27
Q

Fat-soluble vitamin A is important for vision. what are the deficiencies?

A

night blindness, xerophthalmia, keratomalacia

28
Q

Fat soluble vitamins: vitamin D= calciferol is

A

mineralization of bone. get it from the sun

29
Q

deficiencies of vitamin D= calciferol

A

rickets (children), osteomalacia, osteoporosis

30
Q

fat soluble vitamins: vitamin E is tocopherols=

A

antioxidant

31
Q

deficiencies of vitamin E

A

RBC breakage, nerve damage

32
Q

vitamin K= phylloquinone, menaquinone

A

blood clotting protein synthesis, bone protein synthesis

33
Q

what are the deficiency of vitamin K

A

hemorrhaging

34
Q

types of fat soluble vitamins (4)

A
  1. A, D,E, K