biochem exam 2- heme synthesis/degradation

Question 1

glycine+succinyl CoA=

Answer 1

Heme

Question 2

Enzymes and their inhibitors/activators (in order of the pathway)

Answer 2

ALAS 1: inhibited by heme
ALAS 2: inhibite by lack of iron (iron is an activator)
S-aminolevulinic acid dehydratase: inhibited by lead
Ferrochelatase: inhibited by lead

Question 3

heme degradation (two)

Answer 3

1. heme
2. biliverdin-bilirubin

Question 4

heme degradation: heme: biliverdin by _______.

Answer 4

heme oxygenase

Question 5

converting heme to biliverdin by heme oxygenase step releases _______ which is main step that creates _____ in our body

Answer 5

1. carbon monoxide
2. CO

Question 6

Biliverdin—-biirubin

Answer 6

biliverdin reductase