biochem exam 2- urea cycle Flashcards
1
Q
what is the rate-limiting enzyme in urea cycle
A
rate-limiting enzyme: carbamoyl phosphate synthetase 1
2
Q
where does urea cycle occur?
A
mitochondrial matrix AND cytosol
3
Q
In mitochondrial matrix, carbamoyl phosphate synthetase 1 — ______—- goes into cytosol
A
L-citrulline
4
Q
in cytosol, _________ comes in, _______ releases urea, L-ornithine is transported back into the mitochondria + is converted back to L-citrulline
A
aspartate, arginase
5
Q
where does urea get its N and C atoms?
A
N: from NH3 (ammonia), aspartate
C: from CO2
