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FA: random > Biochem > Flashcards

Biochem Flashcards

1
Q

Lab findings/screen of down syndrome before birth

A

quad screen: decreased AFP & estriol; increased Beta-hCG & inhibin A
increased nuchal in 1st trimester translucency on ultrasound

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2
Q

Lab findings/ screen of trisomy 18 (Edwards) before birth

A

quad screen: decreased AFP, Beta-hCG, estriol; normal inhibin A

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3
Q

Lab findings/ screen of trisomy 13 (Patau’s) before birth

A

decreased free Beta-hCG, PAPP-A

increased nuchal translucency

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4
Q

increased RBC fragility

A

vit E deficiency

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5
Q

Dermatitis, cheoliosis, glossitis

A

B2 deficiency

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6
Q

Peripheral neuropathy, glossitis

A

B12 deficiency

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7
Q

hemorrhagic dz

A

Vitamin K deficiency

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8
Q

dermatitis, diarrhea, dementia

A

Vit B3 deficiency

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9
Q

Megaloblastic anemia

A

Vit B12 or Folate deficiency

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10
Q

pernicious anemia

A

Vit B12 deficiency

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11
Q

Bitot spots, keratomalalcia, xerophthalmia

A

Vit A deficiency

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12
Q

Osteomalacia & Rickets

A

vit D deficiency

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13
Q

Acne & psoriasis association

A

vit A

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14
Q

oxidation / reduction rxn association

A

vit B2 & B3

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15
Q

carboxylation rxn association

A

Biotin (vit B7)

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16
Q

hydroxylation of propyl residue association

A

vit C

17
Q

Requires IF for absorption

A

vit B12

18
Q

deficiency in kidney disease

A

vit D

19
Q

vitamins used in pyruvate DH & alpha-KG DH

A

vit B1, B2, B3, B5, lipoic acid

20
Q

vitamin given prophylactically to newborn

A

vit K

21
Q

vitamin used to elevate HDL & lower LDL

A

niacin (vit B3)

22
Q

deficiency caused by INH use

A

vit B6

23
Q

Cobalt w/in vitamin structure

A

vit B12

24
Q

vitamin critical for DNA synthesis

A

folate & B12

25
Q

Metabolism in the mitochondria

A

FA oxidation (Beta-oxidation); acetyl-CoA production; TCA cycle; oxidative phosphorylation

26
Q

Metabolism in the cytoplasm

A

Glycolysis; FA synthesis; HMP shunt; protein synthesis (RER); Steroid synthesis (SER); cholesterol synthesis

27
Q

Metabolism in both mitochondria & cytoplasm

A

Heme synthesis; Urea cycle; Gluconeogenesis

28
Q

Define kinase

A

uses ATP to add high energy phosphate group onto substrate (phosphofructokinase)

29
Q

Define phosphorylase

A

adds inorganic phosphate onto substrate w/o using ATP (glycogen phosphorylase)

30
Q

Define phosphatase

A

Removes phosphate group from substrate (fructose-1,6-bisphosphatase)

31
Q

Define Dehydrogenase

A

catalyzes oxidation - reduction rxn (pyruvate DH)

32
Q

Define carboxylase

A

Transfers CO2 groups w/ help of biotin (pyruvate carboxylase)

FA: random (15 decks)

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