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BIOCHEM Flashcards

IDENTIFICATION

1
Q

What amino acids confer rigidity to
the collagen structure to give it it’s tensile strength?

A

Proline (P)

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2
Q

What amino acids is important in collagen crosslinking, making the collagen insoluble in solvents

A

Lysine (K)

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3
Q

AA that is the precursor for GABA (Gamma
Amino Butyric Acid)

A

Glutamate (E)

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4
Q

An amino acids that is known to be the committed & rate limiting step in heme synthesis.

A

Glycine (G)

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5
Q

Refers to be the collection of entire genetic information of an organism?

A

Genome

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6
Q

Basic unit of heredity

A

Gene

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7
Q

Glycogen Storage Diseases Type 0 is also known as?

A

NONE

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8
Q

Glycogen Storage Diseases Type Ia is also known as?

A

Von Gierke Disease

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9
Q

Glycogen Storage Diseases Type Ib is also known as?

A

NONE

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9
Q

Glycogen Storage Diseases Type VI is also known as?

A

Hers’ Disease

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10
Q

Glycogen Storage Diseases Type IV is also known as?

A

Andersen’s Disease

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11
Q

Glycogen Storage Diseases Type II is also known as?

A

Pompe Disease

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12
Q

Glycogen Storage Diseases Type III is also known as?

A

Cori or Forbe’s Disease

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13
Q

Glycogen Storage Diseases Type V is also known as?

A

McArdle’s Disease

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14
Q

Glycogen Storage Diseases Type VII is also known as?

A

Tarui’s Disease

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15
Q

Give the enzyme deficient of type 0 glycogen storage disease

A

Glycogen Synthase

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16
Q

Give the enzyme deficient of type Ia glycogen storage disease

A

Glucose 6 Phosphatase

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17
Q

Give the enzyme deficient of type Ib glycogen storage disease

A

Glucose 6 Phosphate Translocase

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18
Q

Give the enzyme deficient of type II glycogen storage disease

A

Lysosomal Alpha(1,4) Glucosidase

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19
Q

Give the enzyme deficient of type III glycogen storage disease

A

Glycogen De branching Enzyme

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20
Q

Give the enzyme deficient of type IV glycogen storage disease

A

Glycogen Branching Enzyme

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21
Q

Give the enzyme deficient of type V glycogen storage disease

A

Muscle Glycogen Phosphorylase

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22
Q

Give the enzyme deficient of type VI glycogen storage disease

A

Liver Glycogen Phosphorylase ; Muscle Phosphoglycerate Mutase

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23
Q

Give the enzyme deficient of type VII glycogen storage disease

A

Muscle Phosphofructokinase

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24
What pyrimidine bases can only be found in the RNA and not in DNA?
Uracil (U)
25
What pyrimidine bases can only be found in the DNA and not in RNA?
Thymine (T)
26
What pyrimidine bases is present in both DNA and RNA
Cytosine (C)
27
It is known to be the bond between the Oxygen part of the Phosphate group and the Pentose Sugar in pairs of Nucleotides. What is the bond called?
Phosphodiester Bond
28
Vitamins that is important to prevent pellagra
vitamin B3 (Niacin)
29
Vitamins that is important to prevent scurvy
Vitamin C (Ascorbic acid)
30
Vitamine B9 is also called
Folic acid
31
This vitamin is important to prevent Beri-beri
Vitamin B1 (Thiamine)
32
This vitamin is important to prevent megoblastic anemia
Vitamin B9 (Folic acid)
33
Vitamin B12 is also called?
cobalamin
34
Which water soluble vitamin is known to be Vitamin B5?
Pantothenic Acid
35
Which carbohydrate metabolism that happens when glucagon levels are high?
Gluconeogenesis
36
A carbohydrate metabolism that involves in the production of glucose from non-carbohydrate sources
Gluconeogenesis
37
What do you call the breakdown of glucose
Glycolysis
38
What do you call the synthesis of Glycogen, are both promoted by high insulin levels.
Glycogenesis
39
Which genetic disorder is also known as “Edwards’ syndrome"?
Trisomy 18
40
The breakdown of Glycogen from storage to Glucose, and is stimulated by Glucagon too.
Glycogenolysis
41
The following is the simplest monosaccharide having the lowest number of carbon atoms in its structure?
Glyceraldehyde
42
The inactive form of an enzyme is called?
Zymogen
43
Review about the Organelles of the Cell: Sites of lipid or fatty acid synthesis
Smooth endoplasmic reticulum
44
Review about the Organelles of the Cell: Sites of protein synthesis
Rough endoplasmic reticulum
45
Review about the Organelles of the Cell: "Suicides sacs" that contains hydrolytic enzymes
Lysosome
46
Review about the Organelles of the Cell: Organ for protein synthesis
Ribosomes
47
Review about the Organelles of the Cell: "Swimming pool of the cell" contains the different organelle
Cytosol
48
Review about the Organelles of the Cell: Barrier of protection
Cell membrane
49
Review about the Organelles of the Cell: Rigidity and Protection
Cell wall
50
Review about the Organelles of the Cell: Storage site, post translational process of proteins
Golgi apparatus
51
Which vitamin causes Red Blood Cell (RBC) fragility when deficient in the body?
Vitamin E
52
What vitamin is the precursor of Coenzyme A
vitamin B5
53
In the process of DNA Replication, which enzyme is responsible in unwinding the double stranded DNA (dsDNA)?
Helicase
54
This DNA polymerase remove RNA primers, fills in the gaps and repair
DNA polymerase I
55
This DNA polymerase edit and proofread in the lagging strands
DNA polymerase II
56
This DNA polymerase verifies the base pairing and adds new nucleotides to create one continuous strand in 5' to 3'
DNA polymerase III
57
In the process of DNA Replication, which enzyme is responsible to relieve the supercoiling of DNA
Topoisomerase
58
Enzymes increase the rate of reactions by:
Decreasing the energy of activation
59
In yeasts, pyruvate is metabolized into:
Ethanol
60
This enzymes is/are used in the clinical diagnosis of acute pancreatitis when its levels are elevated in the body?
Lipase
61
The digestive enzymes of cellular compounds are confined inside what organelle of the cell?
Lysosome
62
Glycerophospholipids is also known as?
Phosphoglycerides
63
What phospholipids is formed when you add glycerol and Phosphatidic acid?
phosphatidylglycerol
64
What phospholipids is formed when you add ethanolamine and Phosphatidic acid?
Phosphatidylethanolamine (Cephaelin)
65
What phospholipids is formed when you add choline and Phosphatidic acid?
Phosphatidylcholine (Lecithin)
66
67
What organelle/s is the site of 𝛽 oxidation, Oxidative phosphorylation, and Kreb’s Cycle?
Mitochondria
68
What organelle/s is the site of Glycolysis and Pentose phosphate PW?
Cytosol
69
These proteins have the skeletal and muscular contraction role in the human body
Actin and Myosin
70
These proteins have the Transport and storage role in the human body
Myoglobin (Muscle) Hemoglobin (Blood) Transferrin (Transport of Iron) Ferritin (Storage of Iron)
71
These proteins have the structural role in the human body?
Collagen Elastin Keratin Fibroin
72
Which of the following is the start codon?
AUG
73
Give the Lipid related diseases with its description of enzyme deficiency: 𝛼 galactosidase
Fabry’s
74
Give the Lipid related diseases with its description of enzyme deficiency: Ceramidase
Farber’s
75
Give the Lipid related diseases with its description of enzyme deficiency: 𝛽 galactosidase
Krabbe
76
Give the Lipid related diseases with its description of enzyme deficiency: Sphingomyelinase
Niemann Pick
77
Give the Lipid related diseases with its description of enzyme deficiency: Hexoaminidase A
Tay Sach’s
78
Give the Lipid related diseases with its description of enzyme deficiency: B-glucosidase
Gauchers
79
Give the Lipid related diseases with its description of enzyme deficiency: Increase in ganglioside
Sandhoff
80
What Amino Acid related diseases with its description of enzyme deficiency: Albinism
Tyrosinase
81
What Amino Acid related diseases with its description of enzyme deficiency: Phenylketonuria
Phenylalanine hydroxylase
82
What Amino Acid related diseases with its description of enzyme deficiency: Maple syrup urine disease
Branched chain ketoacid dehydrogenase
83
What Amino Acid related diseases with its description of enzyme deficiency: Alkaptonuria
Homogentisate oxidase
84
The anabolic process wherein pyruvate is made into glucose?
Gluconeogenesis

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