bio Test 2 Endocrine system Flashcards

1
Q

Endocrine vs Exocrine glands

A

Endo: Secrete hormone directly in suroundings
Exo: Secretion delivered to body cavity/outside body (sweat)
secretion = pas Hormone

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2
Q

similarity to nervous system

A

both are communication system

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3
Q

2 differences from nervous system

A
  1. Produces respond that take longer time to be seen
  2. produces respond that are less specific
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4
Q

2 chemical classes:

A

Derived from amino acids
derieved from Cholesterol

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5
Q

2 chemical classes:
1. derieved from amino acids

A
  • Extracellular receptor (on cell membrane)
  • Circulate freely in blood
  • Hydrophilic
  • CANNOT go across cell membrane freely
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6
Q

2 chemical classes:
2. Derieved from cholesterol

A
  • Intracellular (in cell)
  • Circulate in blood with help of transport protein
  • Hydrophobic
  • Can go across cell membrane freely
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7
Q

What is an Extracellular receptor

A

hormone (amine, peptide, protein) bind to a protein receptor on the cell’s surface
signal sent inside cell causing chain reactions
protein receives a phosphate group + gets activated

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8
Q

What is an Intracellular receptor

A

homone (steroid, thyroid) and receptor enters nucleus + attach to DNA
gene activated + protein produced

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9
Q

What is downregulation

A

Target cells DECREASE # of receptors due to HIGH hormone concentration

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10
Q

What is upregulation

A

Target cells INCREASE # of receptors due to LOW hormone concentration

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11
Q

Goal of regulation loops

A

maintain body conditions within acceptable range by setting up dif. mechanisms when deviations happen

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12
Q

3 components of a loop

A

Sensor: receptor monitors the conditions
Control center: Compares signals from sensors to norms+ activates effector if needed
Effector: gland/organ that work bring conditions back in normal range

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13
Q

What is a positive loop

A

Release of hormone + its increasing concentration lead to more productions of the hormone (ex: oxytocin, birth)

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14
Q

What is a negative loop

A

Release of hormone + increasing concentration to PREVENT more production of the hormone

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15
Q

3 Endocrine glands stimuli:
Non-hormone chemicals
hormones
electrical signals

A
  1. Non-hormone chemicals: receptors on gland sense environment + trigger hormone secretion = respond
  2. Hormone: Many homones produced by hypo + pituitary regulate prod. hormone by other gland
  3. Electrical signals: parasympatic/sympatic divisions of PNS, activate release hormones
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16
Q

Hypothalamus-Pituitary complex:
what does it do (3)

A

1.command center of endocrine sys
2.produce hormone
3.Physically linked by infundibulum

17
Q

Hypothalamus-Pituitary complex:
Anterior pituitary(4)

A

-produces hormones (controlle by hypo hormones)
-hypo hormones circulate inside blood vessel down to pituitary gland
-hypo release hormone = increase secretion of pituitary hormones
-hypo inhibiting hormones = decrease of pituitary hormones

18
Q

Hypothalamus-Pituitary complex:
Posterior pituitary

A

-Ectention of hypo (share neurons)
-store hormone produced by hypo

19
Q

Thyroid gland:
where is it and what does it contains

A
  • located neck region, wrappend around trachea, 2lobes in which parathyroid glands embedded
    -contains Follicules cells filled with Colloid
    -TH produce by Colloid
20
Q

Parathyroid gland:
where and what does it do

A
  • Back of thyroid gland
    participate in regulations of bolld, calcium level with PTH
21
Q

Parathyroid gland:
2 Disorders
1. hyperparathyroidism
2. Hypoparatyroidism

A
  1. PTH overproduction excessive calcium remover from bones, weak bones, fractures
    2.PTH deficiency, very low concentration of calcium in blood, muscle twitching, cramping, spasms
22
Q

Adrenal glands:
what it is and where

A

Masses of cells sitting on top of each kidney

23
Q

Adrenal glands:
2 layers

A

Cortex: outer layer, releases steroid +regulated by anterior pituitary hormone -ACTH
Medulla: inner layer, release amine, controlled by nerve impulses

24
Q

Pancreas
where and part that releases hormones

A

Behind stomach
Islet:
Apha-produce glucagon
Beta-produce Insulin

25
Q

Growth hormone:
Where, fonction, disorders (3)

A

GH
1.Pituitary anterioi
2. Regulate growth + repair body
3.Gigantism children
Acromegaly in adults
pituitary dwarfism

26
Q

Thyroid-Stimulating hormone:
where and fonction

A

TSH
Anterior pituitary
stimulates secretions of TH

27
Q

Adrenocorticotropic hormone:
where + fonction
bleu

A

ACTH
anterior pituitary
stimulates hormone release by adrenal cortex

28
Q

Antidiuretic hormone:
where, fonction, desease (1)
bleu

A

ADH
posterior pituitary
stimulate water reabsortion by kidneys
Diabetes insipiduc: underproduction of ADH= chronic dehydration

29
Q

Triiodothyronine hormone:
Thyroxine
where, function, deseases (3)
mauve

A

T3/T4
Thyroid
regulates body’s basal metabolic rate (energy for vital functions)
Iodine deficiency: impaire prod. t3/t4 Overproduction of TRH and TSH
Hypothyroidism: inflamation of thyroid lead low levels TH blood: low metabolic rate, weight gain…
Hyperthyroidism: Elevate concentration of TH blood caused by tumor on pituitary/thyroid: increase metabolic rate, weight loss…

30
Q

Calcitonin hormone
where, fonction
mauve

A

C cells of thyroid:
reduce blood CA2+ level

31
Q

Parathyroid hormone:
where, fonction, deseases (2)

A

PTH
parathyroid gland
Increase blood CA2+ levels
Hyperparathyroidism: PTH overproduction excessive calcium remover bones, weak bones, fractures
Hypoparathyroidism: PTH deficiency, very low concentration calcium blood, muscle twitching, cramping, spasms

32
Q

Aldosterone hormone:
where, fonction
pink

A

Adrenal cortext
increase blood NA+ levels

33
Q

Cortisol, Corticosterone, Costisone
Where, function, desease (1)

A

Adrenal cortex
increase blood glucose levels
Cushing’s disease: too much cortisol produced= high blood glucose level + lipid dispisitits (face/neck)

34
Q

Epinephrine, Norepinephrine
where, fonction

A

Adrenal medulla
stimulate fight or flight response

35
Q

Insulin hormone:
where, function

A

Pancreas
reduces blood glucose levels

36
Q

Glucagon hormone:
where, fuctions

A

Pancreas
incres blood glucose levels.