bio anthro genetics Flashcards

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1
Q

purines:
pyrimidines:

A

adenine, guanine
thymine, cytosine

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2
Q

Describe the 3 steps of DNA replication

A

1) Initiation- helicase split the double helix open
2) elongation- DNA polymerase 3 works up the leading strand and down the lagging strand ( leading to okazaki fragments), pairing FREE NUCLEOTIDES with complimentary bases
3) termination- stop codon ends replication @ fork

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3
Q

describe the 7 steps of protein synthesis

A

Transcription
1) DNA unzipped
2) mrna aligns with base pairs
3) introns are removed, creating mature mrna
Translation:
4) mrna leaves nucleus and goes to ribosomes
5) trna picks up amino acids
6) mrna binds to anticodons
7) protiens are linked/spliced

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4
Q

describe the steps of Mitosis

A

I PAY MY ASS TWO CHEEKS
1) interphase
G1: cell growth S: DNA replication G2
2) prophase: nuclear membrane breaks down, chromatin forms chromosomes, polar orientation
3) Metaphase:
sister chromatids align at mitotic spindle
4) anaphase:
sister chromatids are separated at centromeres
5) telophase: nuclear membrane reappears
6) cytokinesis: cells separate, organelles reappear

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5
Q

Describe the steps of Meiosis

A

Meiosis 1)
prophase 1: synapsis: homologous chromosomes are joined, crossing over
anaphase 1: homologous pairs seperate
Meiosis 2) now the cells each have 23 chromosomes, and mitosis occurs as per usual

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6
Q

Describe the four postulates of mendelian inheritance

A

fundamental theory of heredity:
1) Principal of dominance
2) Principal of paired factors ( two alleles for each gene)
3) law of segregation: parental alleles segregate during gamete production
4) law of independent assortment

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7
Q

what is it called when genes of nearby locuses on a chromosome stick together

A

linkage disequilibrium

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8
Q

describe the various types of genetic mutation

A

-chromosomal: non disjunction, major parts changed
- error in DNA replication: point, insertion, and deletion mutations.

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9
Q

describe the difference between autosomal recessive and dominant disorders

A

autosomal recessive disorders skip generations
autosomal dominant disorders appear every generation

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10
Q

describe the three types of gene-trait relationships

A
  • polygenic
  • pleiotropic
  • mendelian
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11
Q
A
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