Big Idea 3 Flashcards
Alternative Splicing
a regulated process during gene expression that results in a single gene coding for multiple proteins; particular exons of a gene may be included within or excluded from the final, processed messenger RNA (mRNA) produced from that gene
Aneuploidy
the presence of an abnormal number of chromosomes in a cell (too many or too little)
Cell plate
only in plants; develops at midpoint between the two groups of chromosomes in a dividing cell and that is involved in forming the wall between the two new daughter cells
Centromere
the part of a chromosome that links sister chromatids; during mitosis, spindle fibers attach to the centromere via the kinetochore
Cleavage Furrow
the indentation of the cell’s surface that begins the progression of cleavage, by which animal (some algae) cells undergo cytokinesis; actin and myosin (proteins) form cleavage furrow
Codominance
recessive and dominant traits appear together in the phenotype; creates a new phenotype; ex- red + white = red and white spotted
Incomplete Dominance
dominant and recessive traits blend to form new phenotype; ex- red + white = pink
Conjunction
???
Crossing Over
the exchange of genes between homologous chromosomes, resulting in a mixture of parental characteristics in offspring
Ctokinesis
the cytoplasmic division of a cell at the end of mitosis or meiosis, separating the two daughter cells
DNA
a self replicating material present in nearly all living organisms; carrier of genetic information
DNA ligase
a specific type of enzyme that facilitates the joining of DNA strands together by catalyzing the formation of a phosphodiester bond
Phosphodiester bond
the linkage between the 3’ carbon atom of one sugar molecule and the 5’ carbon atom of another (deoxyribose in DNA and ribose in RNA); strong covalent bonds form between the phosphate group and two 5-carbon ring carbohydrates over two ester bonds
DNA Methylation
the addition of a methyl (CH3) group to the cytosine or guanine nucleotides; methyl group added to fifth carbon of cytosine base or sixth nitrogen of adenine base
DNA polymerase
a type of enzyme that is responsible for forming new copies of DNA
DNA replication
the process by which a double-stranded DNA molecule is copied to produce two identical DNA molecules ; daughter cells of DNA are identical
Epistasis
effect of one gene is dependent on the presence of one or more ‘modifier genes’; one combination of such genes has a dominant effect over other combinations
Euchromatin
a lightly packed form of chromatin (DNA, RNA, and protein) that is rich in gene concentration and is often under active transcription; most of the active portion of genome
Helicases
enzymes that bind and may even remodel nucleic acid or nucleic acid protein complexes; RNA and DNA helicases; DNA helicases separate double-stranded DNA into single strands during DNA replication
Hemizygous
characterized by one or more genes that have no allelic counterparts (X paired with Y or genetic deficiency)
Heterochromatin
a tightly packed form of DNA; many functions including gene regulation; constitutive (affect genes near them.. repetitive, forms centromeres and telomeres) or facultative (genes are silenced through mechanism, not repetitive)
Independent Assortment
formation of random combinations of chromosomes in meiosis and of genes on different pairs of homologous chromosomes by passage of one of each diploid pair of homologous chromosomes into each gamete independently of eachother
Inducible Operon
a regulatory repressor protein is normally bound to the operator, which prevents the transcription of the genes on the operon; if inducer is present, it binds to repressor and changes its conformation so that it is unable to bind to the operator
Kinetochore
protein structure on chromatids where the spindle fibers attach during cell division to pull sister chromatids apart