Beta-Lactam Antibiotics Flashcards
1
Q
General mechanism of Beta-lactam Antibiotics
A
Beta-lactam ring binds to the enzyme that forms the cross links in the cell wall to prevent bacterial cell wall synthesis. High internal osmotic pressure leads to lysis eventually.
2
Q
example of beta-lactam-beta-lactamase combination antibioti
A
clavulanate
3
Q
main classes of beta-lactams
A
Penicillins
Cephalosporins
Carbapenems
Monobactams
4
Q
most broad spectrum
A
Carbapenems
5
Q
drug of choice for a very wide range of bacterial infections due to its good safety and efficacy
A
Penicillins
6
Q
essential for antibiotic’s activity
A
beta-lactam ring
7
Q
determines the drug’s antimicrobial and pharmacologic properties
A
side chain
8
Q
Classification of Penicillins
A
Natural Anti-Staphylococcus Aminopenicillins Extended spectrum Beta-lactam-Beta-lactamase inhibitors
9
Q
Natural penicillins examples
A
Penicillin G, K, Na
Benzathine Penicillin
Penicillin VK
