benzodiazepines/antidotes Flashcards
name/classification
activated charcoal
actidose
absorbent
name/classification
actidose
activated charcoal
absorbent
description
activated charcoal
actidose
in a specially prepared charcoal that will absorb and bind toxins from the gastrointestinal tract
indications
activated charcoal
actidose
acute ingested poisoning
precautions
activated charcoal
actidose
administer only after emesis or in those cases where emesis is contraindicated
dosage/route
activated charcoal
actidose
1g/kg mixed with at least 6-8 oz of water then PO or via ng tube
name/classification
naloxone
Narcan
narcotic antagonist
name/classification
Narcan
naloxone
narcotic antagonist
description
naloxone
narcan
naloxone is a pure narcotic antagonist that blocks the effects of both natural and synthetic narcotics and may reverse respiratory depression
indications
naloxone
narcan
narcotic and synthetic narcotic overdose, coma of unknown origin
contraindictions
naloxone
narcan
hypersensitivity to the drug
non-narcotic induced respiratory depression
precautions
naloxone
narcan
possible dependency(including new borns) it has a half life that is shorter than that of most narcotics hence the PT might return to the overdose state
dosage/route
naloxone
narcan
0.4-2mg IV/IM/IN repeat 2-3 min as needed up to 10 mg
pedi dosage/route
naloxone
narcan
0.01 mg IV/IM repeated 2-3 min as needed up to 10 mg
name/class flumazenil
Romazicon
benzodiazapine antagonist
name/class romazicon
flumazenil
benzodiazepine antagonist
description
romazicon
flumazenil
is a benzodiazepine antagonist used to reverse the sedative, recall and psychomotor effects of diazepam, midazolam and other benzodiazepines
indications
romazicon
flumazenil
respiratory depression secondary to the benzodiazepines
contraindictions
romazicon
flumazenil
hypersensitivity to the drug or benzodiazepines, PT’s that take drugs for status epilepticus or seizures, seizure prone PT’s during labor and delivery, tricyclic antidepressent overdose
precautions
romazicon
flumazenil
hepatic impairment, elderly, pregnancy, nursing mothers, head injury, alcohol and drug dependency and physical dependence on benzodiazepines
dosage/route
romazicon
flumazenil
0.2 mg IV over 30 sec/min up to 1mg
name/class lorazepam
ativan
sedative
name/class ativan
lorazepam
sedative
description
lorazepam
ativan
lorazepam is the most potent benzodiazepine available. it has a strong anti-anxiety,sedative,hypnotic, and skeletal muscle relaxant properties, and a relatively short half life
indications
lorazepam
ativan
sedation for cardioversion and status epilepticus
contraindictions
lorazepam
ativan
sensitivity to benzodiazepines
precautions
lorazepam
ativan
narrow angle glaucoma, depression or psychosis, coma, shock, acute alcohol intoxication, renal or hepatic impairment, organic brain syndrome, myasthenia gravis, GI disorders, elderly,debilitated, limited pulmonary reserve
sedation dosage/route
lorazepam
ativan
2-4 mg IM
0.5-2 mg IV
pedi sedation dosage/route
lorazepam
ativan
0.03-0.5 mg/kg IV/IM/PR up to 4 mg
status epilepticus dosage/route
lorazepam
ativan
2 mg slow IV/PR (2mg/min)
pedi status epilepticus dosage/route
lorazepam
ativan
0.1 mg/kg slow IV/PR (2-5 min)
name/class midazolam
versed
sedative
name/class versed
midazolam
sedative
description
midazolam
versed
midazolam is a short acting benzodiazepine with CNS depressant, muscle relaxant, anticonvulsant and anterograde amnestic effects
indications
midazolam
versed
to induce sedation before cardioversion or intubation, seizures
contraindictions
midazolam
versed
hypersensitivity to benzodiazepines, narrow angle glaucoma, shock, coma, or acute alcohol intoxication
precautions
midazolam
versad
COPD
Renal impairment
CHF
Elderly
dosage/route
midazolam
versed
1-5 mg slow IV
pedi dosage/route
midazolam
versed
0.05-0.2 mg/kg IV
0.1-0.15 mg/kg IM
3 mg intranasal
name/class diazepam
valium
antianxirty, hypnotic, anticonvulsant, sedative
name/class valium
diazepam
antianxirty, hypnotic, anticonvulsant, sedative
description
valium
diazepam
diazapam is a benzodiazepine sedative and skeletal muscle relaxant that reduces tremors, induces amnesia, and reduces the incidence and recurrence of seizures. it relaxes muscle spasms in orthopedic injuries and produces amnesia for painful procedures like cardioversion
indications
valium
diazepam
major motor seizures, status epilepticus, pre medication before cardio version, muscle tremors due to injury and acute anxirty
contraindictions
valium
diazepam
shock,coma, acute alcoholism, depressed vital signs, obstretric patients. Neonates
precautions
valium
diazepam
psychoses, depression, myasthenia gravis, due to a short half life of the drug seizure activity may recur
dosage/route
valium
diazepam
seizures:5-10 mg IV/IM acute anxiety: 2-5 mg IV/IM Pedi: 0.5-2 mg IM premedication: 5-15 mg IV Pedi: 0.2-0.5 mg/kg IV