Becky's Random ass stuff Flashcards
What amino acids make up a histone?
Arginine and lysine (positive charge)
What does CpG methylation do to DNA
Makes DNA mute
orange sand in the diaper
Lesch Nyhan Syndrome (sodium urate crystals)
what amino acids are encoded by only one codon?
Methionine (AUG) and Tryptophan (UGG)
rate limiting step of Glycolysis
Phosphofructokinase-1
rate limiting step of Gluconeogenesis
Fructose 1,6 Bisphosphatase
rate limiting step of TCA cycle
Isocitrate dehydrogenase
rate limiting step of Glycogenesis
Gluycogen synthase
rate limiting step of Glycogenolysis
Glyogen phosphorylase
rate limiting step of HMP shunt
Glucose-6-Phosphate dehydrogense
rate limiting step of De novo pyrimidine synthesis
Carbamoyl phosphate synthetase II
rate limiting step of De novo purine synthesis
Glutamine-phosphoriboylpyrophasphate (PRPP) amidotransferase
rate limiting step of Urea cycle
Carbamoyl phosphate synthetase I
rate limiting step of Fatty acid synthesis
Acetyl-CoA corboxylase (ACC)
rate limiting step of Fatty acid oxidation
Carnitine acyltransferase I
rate limiting step of Ketogenesis
HMG-CoA synthase
rate limiting step of Cholesterol synthesis
HMG-CoA reductase
What is mutated in maturity onset diabetes of the young (MODY)?
Glucokinase
What co factor is inhibited by arseni
Lipoic acid
TLC For Nancy are cofactors for what reaction?
Pyruvate dehydrogenase complex (pyruvate–>acetyl-CoA)
alpha-ketoglutarate dehydrogenase complex (alpha ketoglutarte –>succinyl-CoA)
Sx: vomiting, rice water stool, garlic breath
arsenic poisoning
what cytokines do lipoteichoic acids induce?
TNF and IL-1
Caisson disease
air emboli - nitrogen bubbles, decompression sickness
Caplan syndrome
pneumoconiosis and rheumatoid arthritis
Cafe au lait spots unilateral, fibrous dyplasia, endocrine abnormalities
McCune Albright Syndrome
Codman’s triangle
sunburst
Osteosarcoma
Chunks of bone
osteochondroma
soap bubble lesions
osteoclastoma
onion skinning bone lesion
Ewing’s sarcoma