Bchm 2 Flashcards
1
Q
Perilipin
A
- proteins that coat lipid droplets in adipocytes and muscle cells
- regulate lipolysis by controlling physical access to HSL
2
Q
18 of what molecule go in to making cholesterol?
A
acetyl CoA
3
Q
What is the function of lipoproteins?
A
serve as vehicles for transport of cholesterol, cholesterol esters, TAGs, and fat soluble vitamins
4
Q
What Apos are on chylomicron?
A
ApoB-48, ApoC-II, ApoE
5
Q
What Apos are on VLDL?
A
ApoB-100, ApoC-II, ApoE
6
Q
What Apos are on IDL?
A
ApoB-100, ApoE
7
Q
What Apos are on LDL?
A
ApoB-100
8
Q
What Apos are on HDL?
A
ApoA-I, ApoC-II, ApoE
9
Q
Type I Hyperlipoproteinemias
A
- deficiency in ApoC-II or defective lipoprotein lipase
- increased chylomicron and TAG
10
Q
Type IIa and IIb Hyperlipoproteinemias
A
- LDL receptor is completely (IIa) or partially defective (IIb)
- increased cholesterol, LDL, VLDL (IIb only), increased TAG (IIb only; IIa has normal TAG)
