Bchm 1 Flashcards

1
Q

Primary hemostasis

A

formation of primary plug

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2
Q

Factors dependent on Vitamin K

A

2, 7, 9, 10, Protein C, Protein S

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3
Q

aPTT

A
  1. Intrinsic: XII, HMWK, Prekallekrein, XI, IX, VIII
  2. Common: X, V, II, Fibrinogen

25-35 seconds

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4
Q

PT

A
  1. Extrinsic: VII
  2. Common: X, V, II, Fibrinogen

10-13 seconds

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5
Q

Warafarin action

A

vitamin K 2,3-epoxide reductase

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6
Q

What causes the extrinsic pathway? intrinsic?

A
  1. external trauma

2. trauma inside the vascular system

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7
Q

What causes hemophilia A?

A

factor 8 deficiency

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