Bchm 1 Flashcards
1
Q
Primary hemostasis
A
formation of primary plug
2
Q
Factors dependent on Vitamin K
A
2, 7, 9, 10, Protein C, Protein S
3
Q
aPTT
A
- Intrinsic: XII, HMWK, Prekallekrein, XI, IX, VIII
- Common: X, V, II, Fibrinogen
25-35 seconds
4
Q
PT
A
- Extrinsic: VII
- Common: X, V, II, Fibrinogen
10-13 seconds
5
Q
Warafarin action
A
vitamin K 2,3-epoxide reductase
6
Q
What causes the extrinsic pathway? intrinsic?
A
- external trauma
2. trauma inside the vascular system
7
Q
What causes hemophilia A?
A
factor 8 deficiency