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*Haematology + Immunology > BBN Tutorial > Flashcards

BBN Tutorial Flashcards

1
Q

What risks are associated with treating leukaemia in pregnancy?

A

Intensive chemo can induce abortion
Some chemo agents are teratogenic
2-weekly ultrasounds
ATRA

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2
Q

What is the cause of Acute Promyelotic leukaemia?

A

Translocation between chromosomes 15 and 17

PML-RARa fusion gene

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3
Q

How does ATRA (all-trans-retinoic acid) treat Acute promyelotic leukaemia?

A

Forces blasts to differentiate to normal cells

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4
Q

What is the cause of bleeding in acute promyelotic leukaemia?

A

Malignant promyelocytes contain pro-thrombotic granules

Granules trigger coagulation –> blood clots and bleeding

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5
Q

What are the outcomes of AML in first trimester?

A

Successful pregnancy unlikely

Therapeutic termination should be advised

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6
Q

What are the 4 important aspects of disclosing bad news?

A
  1. What does patient already know?
  2. Share the test results
  3. Support patient (acknowledge reaction)
  4. Explain treatment options
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7
Q

What is the SPIKES Model for bad news?

A 
S - setting and listening
P - patient perception
I - Invitation 
K - Knowledge
E - explore emotions/empathise
S - strategy and summary
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*Haematology + Immunology (22 decks)

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