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Microbiology > BBB penetrability of Drugs > Flashcards

BBB penetrability of Drugs Flashcards

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Biology 101 flashcards
1
Q

Excellent with or without inflammation in the brain

A 
Sulfonamides
Chloramphenicol
Trimethoprim
Metronidazole
Rifampicin
Isoniazid
Fluconazole
Flucytosine
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2
Q

Good only with inflammation

A 
Penicillins
Cephalosporins- cefuroximes (2nd gen); 3rd gen parenteral (except cefoperazone); 4th gen imipenem, cilastatin
meropenem
Aztreonam
Ciprofloxacin
Vancomycin
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3
Q

Minimal or not good even with inflammation

A

Aminoglucosides- can pass through BBB in neonates because BBB is still immature
Tetracyclines
Lincosamides
Macrolides

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4
Q

No passage event with inflammation

A

Polymixins
1st and 2nd gen
cephalosporins
Amphotericin B

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Microbiology (7 decks)

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