BBB Flashcards
1
Q
What is the function of the BBB?
A
helps maintain a stable microenvironment for the proper functioning of neurons within the central nervous system
2
Q
What cells regulate the BBB?
A
astrocytes
3
Q
What is the BBB?
A
barrier between the circulation and the interstitial fluid
physical, transport and metabolic barrier
4
Q
How do substances move across the BBB?
A
transport proteins receptor-mediated transcytosis adsorptive transcytosis paracellular aqueous pathway transcellular lipophillic pathway
5
Q
L-DOPA
A
drug used to treat Parkinson’s disease
6
Q
Route by which most CNS drugs enter the brain
A
transcellular lipophillic pathway
7
Q
Areas of the brain that lack the blood brain barrier
A
Area postrema choroid plexus of the 3rd and 4th ventricles pineal gland subformical organ vascular organ of the lamina terminalis