BBB Flashcards

1
Q

What is the function of the BBB?

A

helps maintain a stable microenvironment for the proper functioning of neurons within the central nervous system

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What cells regulate the BBB?

A

astrocytes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What is the BBB?

A

barrier between the circulation and the interstitial fluid

physical, transport and metabolic barrier

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

How do substances move across the BBB?

A
transport proteins
receptor-mediated transcytosis
adsorptive transcytosis
paracellular aqueous pathway
transcellular lipophillic pathway
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

L-DOPA

A

drug used to treat Parkinson’s disease

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Route by which most CNS drugs enter the brain

A

transcellular lipophillic pathway

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Areas of the brain that lack the blood brain barrier

A
Area postrema
choroid plexus of the 3rd and 4th ventricles
pineal gland
subformical organ 
vascular organ of the lamina terminalis
How well did you know this?
1
Not at all
2
3
4
5
Perfectly