Basic Science Flashcards

1
Q

Which layer of articular cartilage… has chondrocytes and collagen fibrils aligned PERPENDICULAR to the joint surface?

A

DEEP / RADIAL layer

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2
Q

Which layer of articular cartilage… contains TYPE X collagen?

A

CALCIFIED cartilage zone

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3
Q

BRITTLE materials fail in ____

A

fail in TENSION (at relatively low strain)

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4
Q

Which layer of articular cartilage… has the highest content of collagen and the lowest concentration of proteoglycan?

A

SUPERFICIAL layer

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5
Q

Which layer of articular cartilage… is responsible for distributing loads and resisting compression?

A

DEEP / RADIAL layer

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6
Q

What shape are the chondrocytes in the: DEEP zone

A

columns

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7
Q

What are the 4 layers of ARTICULAR cartilage?

A

(1) Superfiical (2) Transitional (3) Deep / Radial (4) Calcified

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8
Q

Which layer of articular cartilage… is composed almost entirely of proteoglycans?

A

TRANSITIONAL zone

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9
Q

With polyethylene debris, macrophages release ____, which activates osteoclasts

A

TNF alpha

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10
Q

What shape are the chondrocytes in the: SUPERFICIAL layer / TANGENTIAL zone

A

flat chondrocytes

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11
Q

What is the term to describe materials with:

varying mechanical properties with different loading directions?

A

ANISOtropic

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12
Q

Which layer of articular cartilage… has the greatest ability to resist shear stresses?

A

SUPERFICIAL layer

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13
Q

What is the TIDEMARK layer?

A

a basophilic line that straddles the boundary between calcified and uncalcified cartilage

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14
Q

Which layer of articular cartilage… has chondrocytes and collagen fibrils aligned PARALLEL to the joint surface?

A

SUPERFICIAL layer

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15
Q

What is the term to describe materials with:

same mechanical properties in all directions?

A

ISOTROPIC

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16
Q

Which layer of articular cartilage… contains the TIDEMARK layer?

A

CALCIFIED cartilage zone

17
Q

What shape are the chondrocytes in the: TRANSITIONAL zone

A

spherical

18
Q

Teripartide activates receptors on _____

A

osteoblasts