Basic principles

Question 1

Recall the enzyme inducers and inhibitors.

Answer 1

Question 2

What is given for the first infusion for paracetemol overdose?

Answer 2

150 mg/kg 1 hour

Question 3

What is given for the second infusion for paracetemol overdose?

Answer 3

50 mg/kg 4 hours

Question 4

What is given for third infusion for parectemol overdose?

Answer 4

100 mg/kg 6 hours

Question 5

Gentamicin levels normally

Answer 5

one-hour (‘peak’) serum concentration should be 5–10 mg/litre; pre-dose (‘trough’) concentration should be less than 2 mg/litre.

Question 6

Gentamicin for endocarditis

Answer 6

one-hour (‘peak’) serum concentration should be 3–5 mg/litre; pre-dose (‘trough’) concentration should be less than 1 mg/litre

Question 7

Acute pain management

Answer 7

The BNF advises that 5mg IV morphine every 4 hours is an appropriate starting dose for the management of acute pain.

Question 8

What is the maximum dose of paracetmeol if the patient is below 50KG?

Answer 8

i n this case, as the patient weighs less than 50 kg, the dosage of paracetamol should be reduced to 500 mg PO QDS to avoid the risk of toxicity.

Question 9

How is afternoon hyperglycaemia managed in diabetics?

Answer 9

Increase the morning biphasic insulin aspart Novomix. Do not in the afternoon as fear of morning hypos.

Question 10

What is 1:10,000?

Answer 10

1:1,000 ratio for epinephrine represents 1 gram of epinephrine in 1,000 mL of solution