Basic Physiology of Female Repro System Flashcards
Where does fertilisation usually occur?
Distal 1/3rd of tube
When does the endometrium shed?
When the levels of progesterone and oestrogen are low
How many days is in the fixed part of the menstrual cycle?
14 days in
Which hormone triggers ovulation?
LH
Dual role of oestrogen
- Low oestrogen concentration –> negative feedback
2. High oestrogen concentration –> positive feedback
GnRH meaning
gonadotrophin releasing hormone
Positive feedback of the cycle occurs at which days
during days 12-14
Negative feedback of the cycle occurs
throughout most of the cycle
two phases of the ovarian cycle
- Follicular Phase
2. Luteal Phase
Hormones that high levels at ovulation
LH
FSH (slight surge)
Oestrogen
3 phases of the uterine cycle
- 0 days = menses
- 7 days = proliferative phase
- 14 days = secretory phase
Physiology of the ovarian cycle in the follicular phase
- Primary follicle
- Theca
- Antrum
THEN OVULATION
Physiology of the ovarian cycle in the luteal phase
OVULATION
- corpus luteum formation
- corpus luteum matures
- corpus albicans
Role of GnRH
stimulates LH and FSH secretion from the anterior pituitary
Role of LH from anterior pituitary
Maintains dominant follicle Induces follicular maturation and ovulation stimulates Corpeus luteum function Triggers ovulation Controls the secretion of progesterone
Role of FSH from anterior pituitary
Stimulate follicular recruitment and development
Another name for oestradiol
oestrogen
What cells is oestradiol released from
Granulosa cells
Role of oestrogen
supports female secondary sexual characteristics
negative feedback control of LH and GnRH except for late follicular phase
Positive control of LH surge
Stimulates proliferative endometrium
Systemic effects of oestrogens
Protein metabolism Carbohydrate metabolism Lipid metabolism water and electrolyte balance Blood clotting
What hormone is responsible for the inhibition of lactation?
Progesterone
What is another name for the dominant follicle?
Graafian Follicle
Function of prolactin
promotes lactation in women after childbirth