Basic & Innate Immunity Flashcards
Immunosuppression
When the cell recognizes the object as non-self but doesn’t respond.
Example: AIDS, pregnancy etc.
Autoimmune/erroneously
Target self as known self.
if the receptors are not destroyed in the thymus or bone marrow before the cell matures, it may see self as an invader
Hypersensitivity/allergies
An over reaction response to a foreign entity
Neutrophils
Does phagocytosis, it’s a small number and then expire when it’s full
Monocytes
Are premature macrophages, they can eat a lot more than neutrophils by phagocytosis
Lymphocytes
Govern acquired immunology
( B cells, T cells [Th, Tc], NK)
-spend a lot of time in the lymphatic system and they are also in the blood
Basophils
“911 dispatchers” they detect problems and initiate response
Eosinophils
Jack of all trades, pokes holes in worms and other large parasites
-they cannot eat/phagocytosis
Granulocytes
A cell with granules and have many vesicles with chemical mediators (molecules involved in immune response)
Which three leukocytes are granulocytes
- ) lymphocytes
- ) Basophils
- ) Eosinophils
Which two leukocytes are phagocytes?
Neutrophils and monocytes
What’s the difference between a monocyte and a macrophage?
Monocytes are located in the blood and they are in the inactive (off)form of a macrophage.
Macrophages (out of blood) eat when they are in their active state
What’s the difference between a mast cell and a basophil?
Basophils are stationed in the blood and a mast cell is station outside of the blood, lymphatic system.
- they both have the same function just located elsewhere
What are the three lines of defense that protects our body?
- ) surface barriers
- ) innate immunity
- ) acquired immunity
Surface barriers
Prevents pathogens accessing the the body
- skin, lysozyme in tears, urine, Saliva
