Basic Concepts Flashcards

1
Q

From which germ layer to bone, muscle and connective tissue arise from?

A

The mesoderm

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What are the functions of bone?

A

Support - to stand up
Protection - eg ribs protect lungs
Metabolic - Store of calcium and phosphate
Storage - stores minerals, proteins and fat
Movement (I.e. joints) - as levers
Haematopoiesis - For the production of blood cells.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What are the functions of skeletal muscle?

A
Locomotion (the ability to move)
Posture 
Metabolic 
Venous return - leg muscles 
Heat production 
Continence - pelvic floor
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What are the types of connective tissue (and their functions)?

A

Tendons - Force transmission of muscle-bone
Ligaments - Support bone-bone
Fascia (sheets of connective tissue) - compartmentalisation and protection
Cartilage:
Articular (end of bone contributing to joints and made of hyaline cartiladge)- decreased friction
Fibrocartilage - Shock absorption and increased boney congruity
Synovial membrane -secretes synovial fluid for joints and tendon lubrication
Bursa - Synovial fluid-filled sacs to protect tendons, ligaments ect from friction.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What things give bone its mechanical properties?

A

Collagen and Calcium phosphate

Calcium phosphate - compressive strength
Collagen - tensile strength

The calcium and the phosphate can be liberated or stored depending on loop levels.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What are the two types of bone?

A

Compacts bone

Spongy bone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What are the classifications of bone?

A
Long bone (humerus / femur) - act as levers 
Short bones (as long as they as wide) -work together to give us a great range of movement
Flat bones (sternum / skull) - Protection
Sesamoid bone - protective and mechanical functions 
Irregular bone (vertebrae) -most abundant in axial skeleton in midline.
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What is the major blood supply to bones called? What are the supplementary vessels called?

A

Major : Nutrient artery

Superficial arteries of bone : Periosteal arteries

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What is the role of the epiphyseal artery?

What happens if this blood supply is cut off.

A

This is the blood supply to the epipphyses (end of bone, where growth occurs).

If blood supply is cut off, you get avascular necrosis. This condition is particularly important in fractures of the scaphoid an neck of femur.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What are the important concepts of joints?

A

They connect one bone to another
Greater variation in range of movement
Range of movement is related to stability. - They higher the range of movement, the less stable.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What are the three classifications of joints?

A

Fibrous joints
Cartilaginous
Synovial

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What are fibrous joints?

A

Essentially collagen fibre joining bones.
Very limited mobility.
Found where great strength and stability are required.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What are cartilaginous joint?

A

Cartilage acts as ‘glue’ holding bones together.
Limited mobility
Two types (primary and secondary)
Found at ends of growing bones to along the midline of the adult.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What are synovial joints?

A

Separate bones are capped by smooth articular cartilage with a thin film of synovial separating them .
Highly mobile
Found all over the skeleton

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What are the types of synovial joints?

A

Plane (feet) - flat surfaces that slide against each other.
Hinge (elbow) - only one direction
Pivot (elbow) - peg in hole -allows pronation and supernation
Saddle (like Pringles) - movement in PCR plane
Candyloid
Ball and socket

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What are these points of attatchment?
Origin?
Insertion?

A

Origin: Proximal anchor point (stationary)
Insertion: Mobile distal attachment point

17
Q

What do muscles do and where do they act?

A

MUSCLES CAN ONLY PULL!
Muscles can only act on the joints (and tendons ) they cross.
They also usually work together, coordinated by brain and spinal chord.
All muscles have a trade off between the range of movement and force generation. The larger the force, the smaller the range of movement.

18
Q

What do the orientation of the muscle fibres tell us?

A

Tells us the direction of function.

19
Q

Where are muscles found?

A

Muscles are found within fascia compartments.

The muscles within a compartment share a common innervation and action (generally).

20
Q

How do we predict what a muscle does?

A

Where does it attach?
How many joints does it cross?
How is it related to the joint (eg anterior / posterior ect..)
What direction do the fibres run in?

21
Q

What is another term for the superficial fascia?

A

Subcutaneous fat
Subcutis
Hypodermis

22
Q

What is another term for the deep fascia?

A

Epimysium of muscle

23
Q

How do you get skin creases?

A

Adhesion of skin to underlying fascia creates skin creases

24
Q

Why do tendons heal slowly?

A

Poor blood supply

Low water content so, it doesn’t facilitate the diffusion of nutrients very well.

25
Q

Ligaments

A

Ligaments can change during pregnancy -collagenase relaxes them
Ligaments involved in arches of the foot.
Periarticular ligaments are thick regions of the joint castle.

26
Q

What are aponeurosis?

A

Flattened tendon

Can connect muscle to muscle and sometimes, muscle to bone.

27
Q

What genes regulate body segmentation?

A

Hox genes

28
Q

What effect can mutations of HOX genes have?

A

Can give you an extra lumbar vertebrae
Can give you polydactyl
Can give you an extra rib (in your neck)

29
Q

What is serial homology?

A

Across the body segments, there are the same kinds of recipes that make up each segment.
Eg upper and lower limbs are SERIALLY. HOMOLOGOUS. E.G. femur and humorous are the same.

30
Q

Why do upper limbs rotate outwards and lower limbs rotate inwards?

A

Because in development, the lower limb rotated internally and upper limb rotated externally.

31
Q

Why are fascia compartments useful?

A

Each compartment has a:

Similar action
Usually identical innervation
Similar blood supply