Basal ganglia Flashcards

1
Q

functional basal ganglia

A
caudate nucleus
putamen
globus pallidus - interna&externa
subthalamus
substantia nigra:
pars compacts, pars reticulata
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2
Q

what part of substantia nigra contains melanin?

A

Pars compacta

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3
Q

What produces dopamine?

A

pars compacta

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4
Q

Basal ganglia involved in

A

normal initiation, control and cessation of movement

as well as

cognitive processes and emotion

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5
Q

Internal circuitry of basal ganglia

A
  1. Cortex excites
  2. Caudate + putamen =striatum
  3. Inhibits globus pallidus interna, substantia nigra, pars reticula
  4. inhibits thalamus
  5. excites cortex
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6
Q

The direct pathway + effect on movement

A

leads to excitation of the cortex from the thalamus

facilitates ongoing movement

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7
Q

The indirect pathway

A

Leads to inhibition of the cortex from the thalamus

inhibits unwanted movement

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8
Q

in terms of contraction and relaxation

A

direct contracts

indirect relaxes

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9
Q

Role of substantia nigra, pars compacta

A

releases dopamine which modulates movement: to INITIATE movement

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10
Q

how does substantia nigra initiate movement

A

two paths which BOTH release dopamine but act on different receptors

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11
Q

substantia nigra has what effect on the receptors… what does this mean

A

excites the direct pathway

inhibits the indirect pathway which removes the inhibition, exciting the cortex

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