Basal Ganglia Flashcards
What is the striatum composed of?
Putamen + caudate
What is the lentiform nucleus composed of?
Putamen + globus pallidus
What is the pallidum composed of?
Globus pallidus + substantia nigra pars reticula
In what way does the basal ganglia direct pathway affect thalamic activity and movement?
Increases thalamic activity - promotes movement
In what way does the basal ganglia indirect pathway affect thalamic activity and movement?
Inhibits thalamic activity - suppresses unwanted movement
Where does the ventral anterior nucleus of the thalamus project to?
Premotor cortex
Where does the ventral lateral nucleus of the thalamus project to?
Primary motor cortex
Where does the ventral posterolateral nucleus of the thalamus project to?
Somatosensory cortex
Where does the lateral geniculate nucleus of the thalamus project to?
Visual cortex
Where does the medial geniculate nucleus of the thalamus project to?
Auditory cortex
What is the action of the striatum on the GPi?
Inhibits GPi
What is the action of the striatum on the GPe?
Inhibits GPe
What is the action of the GPi on the thalamus?
Inhibits thalamus
What is the action of the GPe on the subthalamic nucleus?
Inhibits subthalamic nucleus
What is the action of the subthalamic nucleus on the GPi?
Excites GPi
What effects does dopamine have on the direct and indirect pathways?
Enhances the direct pathway via D1 receptors to promote movement
Inhibits the indirect pathway via D2 receptors to promote movement
