Barbiturates

Question 0

Why have barbiturates fallen out of favor?

Answer 0

the “hangover” effect that results in prolonged drowsiness.

Question 1

What is a barbiturate?

Answer 1

Any drug derived from barbituric acid.

Question 2

Barbiturates are _ salts and are soluble in _ and form highly _ solutions.

Answer 2

sodium
water
alkaline

PH of pentathol is 10-11

Question 3

Barbiturates are incompatible with what drugs?

Answer 3

Opioids
NMBs
Catecholamines

Question 4

Barbiturates are available on as what type of mixture?

Answer 4

Racemic

Question 5

Barbiturates are levorotary isomers of __ and __ and are twice as potent as __.

Answer 5

Thiopental
Thiamylal
dextrorotary isomers

Question 6

Barbiturates are only available as what concentration of solutions?

Answer 6

2.5% (5% is to caustic to vessels!)

Question 7

Prompt awakening from SINGLE dose barbiturates is from what?

Answer 7

REDISTRIBUTION

Question 8

Barbiturates have __ CNS activity, and are formed from uria and __ acid.

Answer 8

NO (weird right?)

malonic

Question 9

Substitution at # 2 & #5 ___ help determine drug ___.

Answer 9

carbons

characteristics