Bacteriology 2 Flashcards
Microbiome
collection of all microbes, such as bacteria, fungi, viruses, and their genes, that naturally live on our bodies and inside us
commensal/mutualism/symbiosis
organisms that are part of normal bowel flora
contaminant
organism groiwng in culture by accident
virulence
The capacity of a microbe to cause damage to the host
prokaryotic gram negs
neisseria
e.coli
klebsiella
Enterobacter spp.
Proteus
Salmonella spp
Shigella spp.
Haemophilus spp.
Pseudomonas,
Bacteroides
gram posiitves
Streptococcus spp.
Staphylococcus spp.
Enterococcus spp
Clostridium/Clostridioides
Fusobacterium spp
gram neg cocci
n. meningitides
n. gonnorhea
how are e.colis differentiated from each other
Biochemical reactions
Antigenic structure of cell wall (serotyping)
O antigens (cell wall) and H antigen (flagella)
gut commensal coliforms
Most strains of Escherichia coli
Klebsiella spp.
Enterobacter spp
Proteus spp
1st line antibiotic for coliforms
gentamicin
what is sepsis mediated by
LPS/endotoxin
sepsis steps
Small blood vessels become “leaky” and lose fluid into the tissues
Lower blood volume requires heart to work harder to maintain oxygenation of tissues (↑HR)
Poor tissue oxygen perfusion mean blood supply to less essential organs (skin, kidneys, liver) is shut down to try to maintain blood supply to brain
what do macrophages release into bloodstream
cytokines
clostridia
anaerobic bacilli
non haemolytic cocci
enterococci
