Antibiotic therapy 1 Flashcards by abbey hart

Q

bacteriostatic

A

inhibit growth of bacteria

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Q

bacteriocidal

A

kill bacteria

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Q

narrow spectrum

A

against gram positive

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Q

broad spectrum

A

against many gram positives and negatives

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Q

has the ideal antibiotic got a long or short half life

A

long

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Q

beta lactam antibiotics

A

penicillins and cephalosporins

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Q

example of cephalosporins

A

Ceftriaxone

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Q

example of glycopeptides

A

vancomycin

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Q

cell wall targeting antibocs

A

penicillins
glycopeptides
cephalosporins

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Q

target of beta lactams

A

penicillin binding proteins

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Q

d-alanine d-alanine

A

component of bacterial peptidoglycan

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Q

what do beta lactams resemble

A

D-alanine D-alanine dipeptide & irreversibly binds PBP

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Q

penicillin assoc

A

ecreted rapidly
safe in pregnancy
safe

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Q

limitations of penicillins

A

allergic
rapid excretion so frequent dosing
resistance

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Q

beta lactamases

A

enzymes which destroy beta lactam ring

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Q

co amoxiclav

A

beta lactam and beta lactamase inhibitor

Q

is flucoxacillin narrow or broad spec

A

narrow

Q

what is resistant to flucox

A

MRSA

Q

what is flucox commonly prescirbed for

A

staph and strep skin infections

Q

beta lactamase resistant form of penicilin

A

temocillin

Q

which penicllin for gram positive organisms

A

flucox

Q

which penicillin for gram pos and neg

A

amoxicillin, co amox, piperacillin/ tazobactam

Q

which penicillin for gram neg

A

temocillin

Q

are penicillins bacteriostatic or cidal

A

cidal

Q

are cephalosporins static or cidal

A

cidal

Q

are cephalosporins broad or narrow

A

broad

Q

what antibocs causes c.diff

A

cephalosporins

Q

are glycopeptides cidal or static

A

cidal

Q

A