Antibiotic therapy 1 Flashcards

1
Q

bacteriostatic

A

inhibit growth of bacteria

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2
Q

bacteriocidal

A

kill bacteria

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3
Q

narrow spectrum

A

against gram positive

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4
Q

broad spectrum

A

against many gram positives and negatives

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5
Q

has the ideal antibiotic got a long or short half life

A

long

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6
Q

beta lactam antibiotics

A

penicillins and cephalosporins

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7
Q

example of cephalosporins

A

Ceftriaxone

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8
Q

example of glycopeptides

A

vancomycin

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9
Q

cell wall targeting antibocs

A

penicillins
glycopeptides
cephalosporins

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10
Q

target of beta lactams

A

penicillin binding proteins

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11
Q

d-alanine d-alanine

A

component of bacterial peptidoglycan

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12
Q

what do beta lactams resemble

A

D-alanine D-alanine dipeptide & irreversibly binds PBP

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13
Q

penicillin assoc

A

ecreted rapidly
safe in pregnancy
safe

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14
Q

limitations of penicillins

A

allergic
rapid excretion so frequent dosing
resistance

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15
Q

beta lactamases

A

enzymes which destroy beta lactam ring

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16
Q

co amoxiclav

A

beta lactam and beta lactamase inhibitor

17
Q

is flucoxacillin narrow or broad spec

18
Q

what is resistant to flucox

19
Q

what is flucox commonly prescirbed for

A

staph and strep skin infections

20
Q

beta lactamase resistant form of penicilin

A

temocillin

21
Q

which penicllin for gram positive organisms

22
Q

which penicillin for gram pos and neg

A

amoxicillin, co amox, piperacillin/ tazobactam

23
Q

which penicillin for gram neg

A

temocillin

24
Q

are penicillins bacteriostatic or cidal

25
are cephalosporins static or cidal
cidal
26
are cephalosporins broad or narrow
broad
27
what antibocs causes c.diff
cephalosporins
28
are glycopeptides cidal or static
cidal
29