Bacterial Virulence Flashcards
1
Q
Define Virulence.
A
The capacity of a microbe to cause damage to the host.
2
Q
What is the function of Adhesins?
A
Attachement of bacteria to the extra cellular matrix of host cells.
3
Q
How does the superantigen TSST-1 act?
A
- it causes toxic shock
- triggers mass cytokine release
4
Q
What bacgterium produces TSST-1?
A
Staph areus
5
Q
The Staph areus toxin, Panton-Valentine Leukocidin can cause what conditions?
A
Necrotizing pneumonia
Severe skin infections
6
Q
A clinically relevant Group A Streptococcus (GAS)?
A
Streptococcus pyogenes
7
Q
Stret pyogenes is __ haemolytic
A
beta
8
Q
What feature of Strep pyogenes enables it to adhere to Keratinocytes?
A
The hyaluronic acid capsule.
