Bacterial/Viral Vaccines Flashcards
What is R0
the number of people that 1 sick person will infect on average
how is the herd immunity threshold calculated
1 - 1/R0
give 3 examples of inactivated vaccines
influenza, polio, cholera
what are the pros and cons of inactivated vaccines
pro = stable + unable to cause inf con = need several doses + need adjuvant
give 2 examples of live attenuated viruses
MMR, Yellow Fever
who should not be offered live attenuated viruses
pregnant, immunocompromised
what is the purpose of an adjuvant
enhances the bodies immune response to a vaccine
what is a common adjuvant used
aluminium hydroxide
give 3 serious reactions from vaccines and the vaccines that can cause them
anaphylaxis - DTP (diphtheria, pertussis, tetanus), Hep B
thrombocytopenia - measles
acute arth - rubella