Bacterial/Viral Vaccines Flashcards

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1
Q

What is R0

A

the number of people that 1 sick person will infect on average

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2
Q

how is the herd immunity threshold calculated

A

1 - 1/R0

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3
Q

give 3 examples of inactivated vaccines

A

influenza, polio, cholera

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4
Q

what are the pros and cons of inactivated vaccines

A
pro = stable + unable to cause inf
con = need several doses + need adjuvant
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5
Q

give 2 examples of live attenuated viruses

A

MMR, Yellow Fever

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6
Q

who should not be offered live attenuated viruses

A

pregnant, immunocompromised

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7
Q

what is the purpose of an adjuvant

A

enhances the bodies immune response to a vaccine

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8
Q

what is a common adjuvant used

A

aluminium hydroxide

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9
Q

give 3 serious reactions from vaccines and the vaccines that can cause them

A

anaphylaxis - DTP (diphtheria, pertussis, tetanus), Hep B
thrombocytopenia - measles
acute arth - rubella

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