Bacterial Regulation Flashcards
2 approaches to regulation
gene regulation, enzyme/protein regulation
Other name for house keeping genes
Constitutive genes
Proteins synthesized when needed
Inducible genes, (such as catabolic genes)
Proteins repressed when not needed
Repressible genes (such as anabolic genes)
Catabolic genes
Inducible
Anabolic Genes
Repressable
Lac Z
Beta-galactosidase,
Hydrolyzes monomers
Lac Y
Lactose permease
Lac A
Acetylates galactosides with Acetyl-Coa
Lac operon repressor gene
LacL (naturally active)
CAP
Catabolite activator protein
CAP regulatory system
Cyclic AMP activated by PEP system, when no glucose present
mRNA attenuation
production of a shortened mRNA, terminated within the leader sequence
Negative control of the TRP operon
TRP repressor, tryptophan acts as a corepressor
Antiterminator stem loop in trp mRNA
2-3 stem loop