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Andrews > Bacterial Diseases 2 Megan's Qs > Flashcards

Bacterial Diseases 2 Megan's Qs Flashcards

1
Q

What produces the blue pigment in pseudomonas? Yellow/green pigment? Black pigment?

A

blue pigment (pyocyanin); yellow-green pigment (fluorescein); black (Pyomelinin)

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2
Q

What causes Ecthyma gangrenosum?

A

pseudomonas

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3
Q

What causes Ecthyma?

A

Ulcerative staph or strep pyoderma

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4
Q

What causes Ecthyma dipthericum?

A

Corynebacterium diphtheria

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5
Q

What causes Ecthyma contagiosum?

A

Orf

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6
Q

How do you treat Hot tub folliculitis with systemic symptoms, and what is the cause?

A

Cipro; pseudomonas

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7
Q

What cells do you see in Malakoplakia and what is the cause?

A

foamy eosinophilic von Hansemann cells (macrophages) containing calcified, concentrically laminated,
intracytoplasmic bodies called Michaelis–Gutmann bodies
a. Sheets of histiocytes (von Hansemann cells) with foamy eosinophilic granular cytoplasm and small,
usually eccentric nuclei
b. Michaelis-Gutmann bodies: Calcified, concentrically laminated intracytoplasmic basophilic bodies

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8
Q

Other name for granuloma inguinale, and cause?

a. Clinically?
b. 3 types?
c. Histo cells?
d. Treatment?

A

Donovanosis; Klebsiella granulomatis
a. painless BEEFY RED ULCERATIVE LESION
b. Ulcerovegetative type, cicatricial, nodular
c. Donovan bodies- Intracytoplasmic bipolar staining, safety pin-shaped, inclusion bodies seen in pale
histiocytes
d. Doxycycline x 3 wks or until healed

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9
Q

Parastized macrophage DDX?

A 
HIS Pen GiRL:
Histoplasmosis
Penicillium marfenii
Granuloma inguinale
Rhinoscleroma
Leishmaniasis
and Blasto, Paracoccidio, Trypanosomiasis, Toxoplasma
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10
Q

What causes a Chancroid?

a. Clinically?
b. TX?
c. Gram stain?

A

Haemophilus ducreyi

a. u/l painful adenitis. may suppurate –> bubo
b. azithro 1 gm x1
c. school of fish pattern with gram neg rods

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11
Q

What does Chlamydia trachomatis cause?

a. which serotypes
b. what are 3 stages
c. treatment

A

lymphogranuloma venereum

a. L1, L2, L3
b. painless ulcer; bubo (+groove sign), anogenital rectal syndrome
c. doxy 100 mg BID x 3 wks

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12
Q

MCC purulent urethritis in men

A

neisseria gonorrhea

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13
Q

fitz-hugh-curtis syndrome

A

acute perihepatitis w/ hepatic capsular adhesions (untreated PID)

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14
Q

risk factor for gonococcemia

a. most common site for septic arthritis
b. culture medium

A

C5-C9 deficiency

a. knee
b. Thayer Martin agar

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15
Q

Rx for uncomplicated gonorrhea

a. dissminated
b. what else should you cover for

A

ceftriaxone 125 mg IM x 1

a. ceftriaxone 1 g IM or IV q24 hr, then cephalosporin x 1 wk
b. cover chlamydia (azithro 1 gm PO x1)

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16
Q

how does meningococcemia present

a. txt
b. contacts

A

angular infarcts w/ erythematous rim and gun-metal gray interior

a. penicillin G 300,000 u/kg/day IV x 10-14 d
b. ppx with rifampin 600 mg PO BID x 2 d

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17
Q

waterhouse-friderichsen syndrome

A

adrenal hemorrhage/infarct 2˚ hypotension in meningococcemia

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18
Q

how does one get vibrio vulnificus

A

raw/undercooked fish, shelffish, raw oysters

v. cholera = watery diarrhea

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19
Q

what are rose spots, what causes them?

A

caused by salmonella typhi
2-5 mm rose-colored macules/papule on anterior trunk btwn nipples & umbilicus
seen in 50-60% after 7-10 d fever/diarrhea

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20
Q

what causes Hebra nose

A

rhinoscleroma (klebsiella rhinoscleromatis)

nasal enlargement, deformity, destruction of cartilage

21
Q

what cells help aide diagnosis of Hebra nose

A 
Mikulicz cells (parasitized histiocytes)
russell bodies (plasma cells with eosinophilic aggregates of immunoglobulin)
22
Q

what do dog bites give you

A

pasturella multocida - capnocytophaga canimorsus (DF-2 gram neg rod)

23
Q

human bits give you what? txt

A

eikenella corrodens

augmentin

24
Q

what causes glanders

A

burkholderia (pseudomonas) mallei

direct contact with horses, mules, donkeys

25
Q

what is the sporotrichoid spread DDx

A 
SLANT
sporotrichosis
leishmaniasis
atypical mycobacterium
norcardiosis
tularemia
26
Q

what causes Melioidosis (whitmore disease)

A

burkolderia pseudomallei

27
Q

MCC chronic LAN in children

a. cause
b. how is it spread
c. cause of oculoglandular syndrome of Parinaud

A

cat scratch ds

a. bartonella henslae
b. cat flea (ctenocephalides felis)
c. oculoglandular syndrome of Parinaud: chronic granulomatous conjunctivitis & preauricular adenopathy from conjunctiva innoculation site

28
Q

cause of bacillary angiomatosis

a. what mediates the Jarisch-herxheimer reaction

A

bartonella henselae, bartonella quintana

a. IL-6 and TNF-alpha

29
Q

what causes peliosis hepatitis

A

bartonella henselae

30
Q

cause of carrion’s disease

a. acute vs chronic and assoc problems
b. txt

A

bartonella bacilliformis

a. acute: oroya fever = 2-6 wks after bite –> hemolytic anemia
chronic: verruga peruana = angiomatous PG like lesions after wks-mos
b. chloramphenicol 2 g daily + beta lactam

31
Q

rocha-lima bodies

A

seen in verruga peruana

purple cytoplasmic inclusion bodies in endothelial cells

32
Q

cause of trench fever

a. vector

A

B. quintana

a. body louse (pediculus humanus corporis)

33
Q

cause of bubonic plague

a. what transmits it
b. comb or no comb
c. txt

A

yersinia pestis

a. xenopsylla cheopis (rat flea)
b. no comb
c. streptomycin 2g/d IM x 10d

34
Q

cause of haverhill fever? other name? presentation?

A

streptobacillus moniliformis

a. rat bite fever (fever + arthritis + rash)

35
Q

other name for icteric leptospirosis? cause? presentation?

A

weil syndrome
leptospira interrogans serotype icterohemorrhagiae

f/c, jaundice, purpura, renal fail, hemorrhage, pulm/liver/encephalitis

36
Q

nonicteric leptospirosis other name? cause?

A

fort bragg fever
leptospira autumnalis
pre-tibial exanthem, fever (3-7 d, followed by 1-2 day absence), conjunctiva, HA

37
Q

cause of Ohara’s ds? other name? soure?

A

francisella tularensis
tularemia
handling wild rabits

38
Q

txt of rickettsial disease

A

doxy 100 mg bid x 7 days

39
Q

cause of endemic typhus? vector? host?

A

R. prowazekii
pediculus humanus var corporis (body louse)
humans and flying squirrels

40
Q

cause of endemic (murine) typhus? vector?

A 
rickettsia typhi
xenopsylla cheopis (rat flea)
41
Q

disease resulting from chiggers bite? cause?

A 
scrub typhus (tsutsugamushi fever)
rickettsia tsutsugamushi
42
Q

cause rocky mountain spotted fever? vectors? reservoir?

A 
rickettsia ricketsii
wood tick - D. andersoni (west US)
dog tick - D. variabilis (east US)
lone star tick - amblyomma americanum
reservoir - dogs, small animals
43
Q

boutonneuse fever cause? vector? indurated papule produced by tick bite?

A

aka mediterranean fever
rickettsia conorii
brown dog tick (rhiphicephalus sanguineus)
tache noir

44
Q

rickettsial pox cause? vector? reservoir? weil-felix positive or negative?

A

rickettsia akari
vector: rodent mite = allodermanyssys sanguineus (blood mite)
reservoir: mus musculus (house mouse)
weil-felix negative

45
Q

human monocytic erlichiosis cause? vector? what is seen on wright-giemsa stain of leukocytes?

A

ehrlichia chafeensis
vector: amblyomma americanum (lonestar tick)
wright-giemsa: mulberry inculsions (morula)

46
Q

cause of human granulocytotropic anaplasmosis? vector?

A

ehrlichia phagocytophilia

47
Q

cause of lyme disease in US? vector? 3 stages? 10% untreated pts get?

A

borellia burgdorferi
vector: ixodes scapularis and dammini (nw/midwest), pacificus (west), ricinus (europe)
stage 1: erythema migrans
stage 2: hematogenous spread, borrelia lymphocytoma = b cell proliferation w/ blue red swelling on ear lobe or areola/scrotum
stage 3: inflamatory, acrodermatitis chronica atrophicans, meningitis/encephalitis
untreated: carditis w/ AV block

48
Q

cause of acrodermatitis chronica atrophicans ‘herxheimer disease’? transmitted by? seen where?

A

borellia afzelii
ixodes ricinus
europe

Andrews (15 decks)

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