Bacteria-Oral Bacteria B-with highlights Flashcards
Endodontic infections are ……………. infections
that are …………………..
Endodontic infections are endogenous infections
that are opportunistic
……………………… infections associated with the
teeth and surrounding supporting
Pyogenic infections associated with the
teeth and surrounding supporting
Bacteria in root canal infections are?
cultivaded
Enterococcus faecilis
• Found often in cases of chronic apical infection and failed root canal treatments • normal levels are very low but this organism is very hardy
Bacteroids and prevotella
Most frequently culticated root canal infections
Anachoresis (3) (via pulpal
…………supply) during
bacteremia from ……………… at different site
Anachoresis (3) (via pulpal
blood supply) during
bacteremia from tooth
extraction at different site
bacteria commonly isolated from dentoaleolar absesses.
Faculative anerobes: Step.
obligate anerobes: prevotella
Ludwigs Angina;
A spreading, …………… infection of the …………….and …………………… spaces.
…………….. of the fascial spaces rather than true …………….. formation.
A spreading, bilateral infection of the sublingual and submandibular spaces.
Cellulitis of the fascial spaces rather than true abscess formation.
Ludwigs Angina
Without treatment
Airway obstruction - death by asphyxiation
without intervention
Mixed endogenous infection:
Porphyromonas spp.
Prevotella spp.
Fusobacteria
Anaerobic streptococci
Localized collection of pus caused by acute or chronic destruction of periodontium
Endogenous, subgingival plaque bacteria
Periodontal Abscess
Suppurative Osteomyelitis of the Jaws
Same organisms as above but involves bone Porphyromonas spp. Prevotella spp. Fusobacteria Anaerobic streptococci
Cervicofacial Actinomycosis
endogenous, granulomatous disease 65% in cervicofacial region Actinomyces (oral commensal) visible granules in pus sulphur granules = collections of bacteria
Oral manifestations of bacterial infections
Syphilis
congenital: Hutchinson’s incisors, mulberry molars
primary and secondary syphilis lesions
gummas (granulomatous lesions)
Oral manifestations of bacterial infections
Tuberculosis
oral lesions in up to 5% of primary and secondary tuberculosis cases
ulcers on palate and gingiva
Leprosy
For leprosy just know there are
many oral manifestations
Bacterial infections of salivary glands are mostly?
often Staphylococcus
Diseases or situations associated with
oral bacteria or their components
Infective endocarditis Disseminated intravascular coagulation Nephritis Rheumatoid arthritis Behçets disease (chronic inflammatory disorder with oral ulcers) Atherosclerosis Low-birth-weight infants
Infective endocarditis
Strep adhere to platelets through?
adhesions and platelettes
Aggrestion of platelets requires crosslinking of?
Fibrogen molecules
Heat shock proteins (HSPs
Microbial HSPs are very similar to human HSPs that are normally shielded
within cells. Antibodies elicited by bacterial HSPs can cross-react with
exposed human HSPs (e.g. present in damaged tissue). If immune
complexes are deposited in the arterial wall (atherosclerosis), joints
(arthritis), or mucous membranes (Behçets disease), HSP mimicry can
contribute to systemic disease.
Autorecognition induced by oral microorganisms
Streptococcus sanguinis express an epitope within PAAP (plateletaggregation
associated protein), which is similar to the arthritogenic epitope
of type II collagen. In a murine arthritis model, S. sanguinis infection
exacerbates arthritis.
Interestingly, exposure of neonatal mice to PAAP+ S. sanguinis inhibited
development of autoimmune arthritis in the adult (early exposure
protective?).
TNF alpha and IL-1beta enter …………and induce the ………… to produce acute phase eractants such a ….CRP
TNF alpha and IL-1beta enter circulation and induce the Liver to produce acute phase reactants such a CRP causing exaberation of existing diseases.
The mucosal barrier
Contains
Toll-like receptors
TLRs recognize PAMPs (Pathogen-
Associated Molecular Patterns)
