Bacteria Derived Enzymes. Flashcards
1
Q
What is the MOA of bacteria derived enzymes?
A
They degrade asparagine which starves rapidly dividing cells.
2
Q
What is the only bacteria derived enzyme?
A
L-asparaginase.
3
Q
What is L-asparaginase used to treat?
A
Large cell lymphoma.
4
Q
Are the many side effects associated with L-asparaginase?
A
No.
5
Q
What is a negative of L-asparaginase?
A
Resistance develops quickly.
