Baby Respi

Question 1

Phase:

main feature Development of Proximal Airways

Answer 1

Embryonic

Question 2

Duration of Embryonic Phase

Answer 2

End of 3rd week to 5th week

Question 3

Lung Bud arises at the level of what pharyngeal pouch

Answer 3

4th

Question 4

In embryonic phase: Increase in what kind of acid in adjacent mesoderm

Answer 4

Retinoic Acid

Question 5

TBX4

Answer 5

induces formation, growth and differentiation of lungs and trachea

Question 6

In the Embryonic Phase what maintains communication with pharynx via laryngeal orifice?
In adults?

Answer 6

Respiratory primordium

in adults: laryngeal opening

Question 7

Main feature of PSEUDOGLANDULAR PHASE

Answer 7

Development of Lower Conducting Airways and Vascular Supply

Question 8

Duration of Pseudoglandular phase

Answer 8

5th week to 16th week

Question 9

What stage of Respiratory Development:
Epithelial differentiation of airways, penetration into coelomic cavity
bronchial buds form main bronchi and then secondary bronchi
cartilagionus and muscular components of trachea and bronchi from splanchic mesoderm (visceral pleura)

Answer 9

PSEUDOGLANDULAR PHASE

Question 10

Fibroblast Growth Factor Family FGFF

Answer 10

Branching continues to form terminal bronchioles

Question 11

Main Feature of CANALICULAR PHASE

Answer 11

Formation of Gas Exchange Units

Question 12

3 major events of CANALICULAR PHASE

Answer 12

Birth of acinus, epithelial differentiation and beginning of surfactant synthesis by type II pneumocytes/ alveolar cells

Question 13

Duration of CANALICULAR PHASE

Answer 13

17th to 24th week

Question 14

Main Feature of SACCULAR PHASE

Answer 14

Initiation of Alveolarization

Question 15

Duration of Saccular phase

Answer 15

24th to 37th week

Question 16

Respiration will only begin to occur in what epithelium?

Answer 16

When epithelium develops into squamos epithelium

Question 17

Surfactant starts to appear in alveolar lung fluid in significant amounts by what week

Answer 17

28th week

Question 18

Dissipation of interstitium occurs at what stage

Answer 18

Alveolar Phase

Question 19

Main feature of Alveolar Phase

Answer 19

Continued Alveolar Development and Proliferation

Question 20

Presence of a posterolateral defect in the diaphragm allowing the intestines to move up
Lung development is affected
Lung hypoplasia

Answer 20

Congenital Diaphragmatic Hernia

Question 21

Muscle weakness allows the intestines to push the diaphragm up
Half of diaphragm has defective musculature and balloons into thoracic cavity–diaphragmatic pouch
results from failure of muscular tissue from the body wall to extend into the pleuroperitoneal membrane on the affected side

Answer 21

Eventration of the diaphragm

Question 22

Abnormal partitioning by tracheoesophageal septum

Answer 22

Tracheoesophageal fistula

Question 23

Deflated lungs from absence of surfactant

Answer 23

Respiratory Distress Syndrome/Hyaline Membrane Disease