B8-046 Female UTI Flashcards

1
Q

cystitis, urethritis, and prostatitis are [upper/lower] UTI

A

lower

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2
Q

pyelonephritis, intra-renal abscess, perinephric abscess is [upper/lower] UTI

A

upper

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3
Q

UTI in healthy patient with functionally normal urinary tract

A

uncomplicated UTI

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4
Q

infection associated with anatomic/functional abnormality of the urinary tract, immunocompromised host, or multi-drug resistant bacteria

A

complicated UTI

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5
Q

pyelonephritis tends to arise from […] UTI

A

ascending

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6
Q

2 consecutive clean catch urine sample growing bacteria in the absence of symptoms

A

asymptomatic bacteriuria

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7
Q

does asymptomatic bateriuria need to be treated?

A

no

only in pregnancy or prior to GU surgery

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8
Q

UTIs in males are [complicated/uncomplicated]

A

complicated

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9
Q

UTIs in pregnancy are [complicated/uncomplicated]

A

complicated

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10
Q

UTIs in children are [complicated/uncomplicated]

A

complicated

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11
Q

UTIs in patients with DM are [complicated/uncomplicated]

A

complicated

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12
Q

genetic factor that provides risk factor for recurrent UTI

A

lewis blood group non-secretor

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13
Q

80% of outpatient UTIs are caused by

A

E coli

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14
Q

major virulence factor of UPEC

A

P pili

(prevents phagocytosis, upregulated in strains that cause pyelonephritis)

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15
Q

fever, chills, flank pain
CVA tenderness

A

pyelonephritis

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16
Q

treatment options for uncomplicated cystitis [3]

A

nitrofurantoin 100 mg BID x5
TMP/SMX BID x 3
fosfomycin 3g x 1

17
Q

why is nitrofurantoin not recommend in pyelonephritis?

A

poor tissue penetration

18
Q

treatment for pyelonephritis [3]

A

floroquinolone x 7 days
TMP/SMX BID x 14 days
oral b lactam x 14 days

19
Q

definition of recurrent UTI

A

3 within 12 months OR
2 in 6 months

20
Q

what diagnostic tool is mandatory for evaluation of recurrent UTI?

A

urine cultures

21
Q

treatment for recurrent UTI in postmenopausal women

A

vaginal estrogen

22
Q

treatment options for UTI in pregnancy [4]

A

penicillins
cephalosporin
nitrofurantoin (hemolytic anemia)
fosfomycin

23
Q

what type of kidney stones are caused by urease producing bacteria?

A

struvite

(Proteus, Klebsiella, S. sapro)

24
Q

intensely pink on MacConkey agar

A

E coli

25
Q

viscous colonies

A

Klebsiella

26
Q

swarming motility pattern

A

proteus mirabilis

27
Q

Leukocyte casts in urine sample may indicate

A

pyelonephritis

28
Q

Alkaline urine (pH > 8) may indicate

A

urease producing organisms

(Proteus, Klebsiella, S. sapro)

29
Q

Positive urinary nitrites indicate

A

bacteria that convert nitrates to nitrites

(most commonly E.coli)
(lack of nitrites does not mean no infection)

30
Q

antibiotic prophylaxis may be considered in all women with

A

recurrent uncomplicated UTIs

(can be continuous or postcoital)

31
Q

first line medications for treatment of UTI [2]

A

nitrofurantoin
Trimethoprim/sulfamethoxazole (TMP/SMX)

32
Q

staghorn calculus is composed of

A

struvite (magnesium ammonium)

33
Q

struvite stones are produced by […] producing bacteria

A

urease

(proteaus mirabilis)

34
Q

symptoms of upper UTI

A

fever
CVA tenderness
chills, malaise (ill appearing)

35
Q

treatment options for uncomplicated pyelonephritis [3]

A

fluoroquinolone x 7 day

TMP-SMX x 14 days

beta-lactam x 14 days

36
Q

not recommended for treatment of pyelonephritis due to poor tissue penetration

A

nitrofuratoin

37
Q

treatment of asymptomatic bacteriuria in pregnancy

A

culture –> appropriate antibiotics

(no cipro or trimethoprim)