B8-046 Female UTI

Question 1

cystitis, urethritis, and prostatitis are [upper/lower] UTI

Answer 1

lower

Question 2

pyelonephritis, intra-renal abscess, perinephric abscess is [upper/lower] UTI

Answer 2

upper

Question 3

UTI in healthy patient with functionally normal urinary tract

Answer 3

uncomplicated UTI

Question 4

infection associated with anatomic/functional abnormality of the urinary tract, immunocompromised host, or multi-drug resistant bacteria

Answer 4

complicated UTI

Question 5

pyelonephritis tends to arise from […] UTI

Answer 5

ascending

Question 6

2 consecutive clean catch urine sample growing bacteria in the absence of symptoms

Answer 6

asymptomatic bacteriuria

Question 7

does asymptomatic bateriuria need to be treated?

Answer 7

no

only in pregnancy or prior to GU surgery

Question 8

UTIs in males are [complicated/uncomplicated]

Answer 8

complicated

Question 9

UTIs in pregnancy are [complicated/uncomplicated]

Answer 9

complicated

Question 10

UTIs in children are [complicated/uncomplicated]

Answer 10

complicated

Question 11

UTIs in patients with DM are [complicated/uncomplicated]

Answer 11

complicated

Question 12

genetic factor that provides risk factor for recurrent UTI

Answer 12

lewis blood group non-secretor

Question 13

80% of outpatient UTIs are caused by

Answer 13

E coli

Question 14

major virulence factor of UPEC

Answer 14

P pili

(prevents phagocytosis, upregulated in strains that cause pyelonephritis)

Question 15

fever, chills, flank pain
CVA tenderness

Answer 15

pyelonephritis

Question 16

treatment options for uncomplicated cystitis [3]

Answer 16

nitrofurantoin 100 mg BID x5
TMP/SMX BID x 3
fosfomycin 3g x 1

Question 17

why is nitrofurantoin not recommend in pyelonephritis?

Answer 17

poor tissue penetration

Question 18

treatment for pyelonephritis [3]

Answer 18

floroquinolone x 7 days
TMP/SMX BID x 14 days
oral b lactam x 14 days

Question 19

definition of recurrent UTI

Answer 19

3 within 12 months OR
2 in 6 months

Question 20

what diagnostic tool is mandatory for evaluation of recurrent UTI?

Answer 20

urine cultures

Question 21

treatment for recurrent UTI in postmenopausal women

Answer 21

vaginal estrogen

Question 22

treatment options for UTI in pregnancy [4]

Answer 22

penicillins
cephalosporin
nitrofurantoin (hemolytic anemia)
fosfomycin

Question 23

what type of kidney stones are caused by urease producing bacteria?

Answer 23

struvite

(Proteus, Klebsiella, S. sapro)

Question 24

intensely pink on MacConkey agar

Answer 24

E coli

Question 25

viscous colonies

Answer 25

Klebsiella

Question 26

swarming motility pattern

Answer 26

proteus mirabilis

Question 27

Leukocyte casts in urine sample may indicate

Answer 27

pyelonephritis

Question 28

Alkaline urine (pH > 8) may indicate

Answer 28

urease producing organisms (Proteus, Klebsiella, S. sapro)

Question 29

Positive urinary nitrites indicate

Answer 29

bacteria that convert nitrates to nitrites (most commonly E.coli) (lack of nitrites does not mean no infection)

Question 30

antibiotic prophylaxis may be considered in all women with

Answer 30

recurrent uncomplicated UTIs (can be continuous or postcoital)

Question 31

first line medications for treatment of UTI [2]

Answer 31

nitrofurantoin Trimethoprim/sulfamethoxazole (TMP/SMX)

Question 32

staghorn calculus is composed of

Answer 32

struvite (magnesium ammonium)

Question 33

struvite stones are produced by [...] producing bacteria

Answer 33

urease (proteaus mirabilis)

Question 34

symptoms of upper UTI

Answer 34

fever CVA tenderness chills, malaise (ill appearing)

Question 35

treatment options for uncomplicated pyelonephritis [3]

Answer 35

fluoroquinolone x 7 day TMP-SMX x 14 days beta-lactam x 14 days

Question 36

not recommended for treatment of pyelonephritis due to poor tissue penetration

Answer 36

nitrofuratoin

Question 37

treatment of asymptomatic bacteriuria in pregnancy

Answer 37

culture --> appropriate antibiotics (no cipro or trimethoprim)