B8-040 Benign Prostatic Hyperplasia Flashcards
most common cause of post-TURP hyponatremia
dilutional
what medications reduce the need for BPH related surgery?
5-a-reductase inhibitors (finasteride)
what is the best indication for treatment of BPH symptoms?
degree of bother
most common location of prostate cancer
peripheral zone
most common location of BPH
transition zone
[…] cancer in the mother is a risk factor for prostate cancer
breast
(BRCA2)
describe what’s going on in these uroflowmetry graphs
a. normal male
b. normal female
c. and d. intermittent flow
e. prolonged weak stream
[…] inhibition leads to prostatic relaxation
a1
block the conversion of T to DHT
5a reductase
older a1 blockers can cause […]
orthostatic hypotension
(doxazosin/terazosin, but cheap)
which a1 blocker has to lowest rate of retrograde ejaculation?
alfuzosin
what medication is able to reduce prostate volume up to 20%?
(show to reduce need for surgery)
5a reductase inhibitors
(finasteride- type 2, dutasteride type 1 and 2)
(du=dual)
NOS mediated smooth muscle relaxation
PDE5 inhibitors
used to relieve irritative symptoms [2]
anticholinergics (oxybutynin)
beta 3 agonists (mirabegron)
AUA recommends […] for prostate cancer screening in men ages 55-70
shared decision making
(1-2 year intervals)
water vapor therapy that uses steam to destroy adenoma
rezum
staple-like implants that hold the prostatic lobes apart
urolift
non-surgical, minimally invasive surgical options [2]
rezum
urolift
historical gold standard prostate surgery
TURP
benefits of laser ablation over TURP
less blood loss
shorter catheterization
outpatient
disadvantage of laser ablation over TURP
no tissue for pathology
surgical technique that has supplanted open surgery removal for very large glands
laser enucleation
laser goes between the prostate capsule and adenoma
tissue then morcellated and pulled out in pieces for pathology
laser enucleation
(great for very big glands)
