B4.038 - Interpreting Arterial Blood Gas Prework 3 Flashcards
step 1 of diagnosing acid base issues
step 1 - what is pH (7.35-7.45)
how do you differentiate if someones disorder is primarily respiratory or metabolic?
respiratory - high or low pCO2 (more than 40 or low) with compensatory bicarb changes
metabolic - changes in HCO3- primarily with compensatory pCO2
how do you know if a respiratory disturbance is acute or chronic
acute - an increase in pCO2 shifts the equilibrium between CO2 and HCO3 to increase HCO3. This occurs almost immediately
chronic - the kidneys respond by retaining HCO3 this takes a few days to fully occur)
what do COPD patients have as far as balance
high HCO3- to compensate for the acidosis they usually have from low ventilation
describe acute respiratory alkalosis
decrease in pCO2 shifts the equilibrium between CO2 and pCO2 to decrease the HCO3- this occurs very quickly
what is winters formula
PCO2 = 1.5 x HCO3 + 8
it tells you if the respiration is adquately compensating for metabolic alidocis
if the actual measured pCO2 is much greater than whats expected according to Winters formula what does that mean
the respiratory system is not fully compensating for the metabolic acidosis and a respiratory acidosis is concurrently present
in emphysema what is pCO2 like
usually elevated, if they have metabolic acidosis the body wants to blow oc CO2 but becaue of emphysema they will have metabolic acidosis and secondary respiratory bc of lack of compensatory ability
when do you calculate anion gap
if there is metabolic acidosis
what is the equation for anion gap
anion gap = [Na+] - ([Cl-] + [HCO3])
what is a normal anion gap
12
what is the electroneutrality principle
for every molecule of unmeasure anion present, one molecule of bicarbonate is lost
if there is an anion gap metabolic acidosis and there are other metabolic derangements present what equation do you use to find corrected HCO3
Corrected HCO3 = measured CO3 + (anion gap - 12)
what is a delta gap
corrected HCO3
if corrected HCO3 is less than normal (22) what does that mean
There is an additional metabolic disorder present