B3.2 The endocrine system Flashcards
What does the endocrine system consist of?
Glands, hormones and receptors
Endocrine glands
Ductless glands that secrete (release) hormones into the blood stream
Are Sweat, Salivary and tear glands part of the endocrine system?
No, they are part of the exocrine system. these glands secrete substances onto an epithelial surface by way if duct.
Hormones
chemical messengers which are secreted by endocrine glands in 1 part of the body and carried via the blood steam to target organs elsewhere in the body.
endocrine system duration of response?
long
Adrenaline
- hormone secreted by the adrenal glands in ‘stressful’ situation to prepare body for ‘fight or flight’ response
- — fight or fight is done to prepare the body for intense physical actions by:
- adrenaline binds to receptors in the heart that causes the heart muscle to contract more frequently and forcefully to increase the heart rate & blood pressure. consequently the blood flows to the muscles increases and the cells receive more O2 and glucose for increased respiration
- adrenaline also binds to the receptors in the liver causing the lover to break down its glycogen stores to release glucose. By increasing the blood glucose level, there is more glucose in the blood to be transported to the cells for increased respiration.
- Breathing rate increases to cope with extra demand for O2
- once the stress / situation stops or is removed adrenaline will stop being produced and the body system returns to its previous state.
Thyroxine
- hormone secreted by the thyroid gland in order to regulate the body’s metabolic rate (the speed at which the body transfers chemical stores in order to perform functions such as growth)
- the thyroid stimulating hormone (THS) which is released from the pituitary gland, stimulates the release of thyroxine
- negative feedback is the system that ensures the thyroxine levels in the blood are normal. it is important in keeping the other internal conditions at a constant. - - when thyroxine levels are too high the secretion of TSH from the pituitary gland is inhibited / stopped / slowed.
- the thyroid gland converts iodine into thyroxine by combining it with an amino acid called tyrosine. if iodine is lacking from the diet the thyroid gland will enlarge in its attempt to produce thyroxine - produces large swelling called a goitre.
Oestrogen and Progesterone
Role - ovulation and menstruation
Gland - ovaries
target organs - uterus, pituitary gland
Oestrogen and progesterone –> pituitary glands and hypothalamus –> LHRH –> pituitary –> LH and FSH –> uterus
Testosterone
Role - gives body its masculine characters - changes during puberty sand sperm production
Gland - testes
target organs - various
ADH
Anti-diuretic hormone regulates water level in the bloodstream
gland - pituitary gland
helps control blood pressure by acting on kidneys and blood vessels. conserves the fluid volume of your body by reducing the amount of water passed out in urine.
Pituitary Gland
The ‘master gland’ - secretes nine hormones that directly regulate many body functions.
Disorders - gigantism is if too much growth hormone is produced in early childhood. too little growth hormone produced can result it pituitary dwarfism.
Negative feedback
A type of control that keeps internal conditions constant in the body.
any change away from normal level brings about mechanisms to reverse the change and bring the levels back to normal - if body temp decreases heating mechanism is activated (shivering), if body temp increases cooling mechanism is activated (sweating)
Controlling Thyroxine if needed
- Thyroxine controls how much energy is available to cells. the hypothalamus detects if more is needed. it causes the pituitary gland to release TSH (thyroxine stimulating hormone.) this causes the Thyroid to release thyroxine. this increases the metabolic rate and energy available to cell
Negative feedback practical
Equipment - beaker, Bunsen burner, safety mat, tripod, gauze, thermometer, safety glasses
Half - fill beaker with water
Heat water to exactly 50 degrees Celsius and try to maintain it at this temp for 10 mins
Controlling Thyroxine if not needed
Hypothalamus detects when cells have enough energy. It then stops the pituitary gland from producing TSH. the thyroid gland stops producing thyroxine and less energy is released to cells.
Stages in the menstrual cycle - the follicle
- girls are born with thousands of follicles (potential eggs) in each ovary
- At puberty some of the follicles start to develop - the cell divides by meiosis halving the number of chromosomes in the nucleus
- A follicle starts to develop at the start of the cycle - it enlarges and fills with fluid - after 2 weeks it bursts and releases the egg - this is ovulation. Follicle cells left behind form the yellow body (corpus luteum) which supports the lining of the uterus during pregnancy.