B3 The upper GI tract 2 Flashcards
What are the NT and receptors in the pre ganglionic nerve in the sympathetic system?
NT- ACh
receptor - nicotinic
What are the NT and receptors in the post ganglionic nerve in the sympathetic system?
NT- NA
receptor- adrenoceptors
What are the NT and receptors in the pre ganglionic nerve in the parasympathetic system?
NT- ACh
receptor- nicotinic
What are the NT and receptor in the post ganglionic nerve in the parasympathetic system?
NT- ACh
receptor- muscarinic
What is an agonist at alpha and beta adrenoceptors?
Noradrenaline
What is a beta blocker antagonist at beta adrenoceptors?
Atenolol
What is an agonist at muscranic receptors?
Acetylcholine
What is an antagonist at muscarinic receptors?
Atropine
What is the function of saliva?
1) aids speech
2) promotes dental hygiene
3) allows mastication
4) adds fluid
5) starts digestion of starches - amylase
What do Acinar cells secrete?
amylase and electrolytes with similar tonicity to plasma
What modify secretion of saliva?
Striated and excitatory ducts
What are the side effects of some drugs which produce a secondary action to block muscarinic receptors (antimuscarinic)?
1) dry mouth
2) constipation
3) blurred vision
4) urinary retention
What causes enhanced muscarinic activity?
muscarinic agonists
acetylcholinerase
both cause salivation
What causes increase in acid secretion?
1) histamine via H2 receptors
2) gastrin
3) acetylcholine via M-receptors M3 on parietal cells
What causes a decrease in acid secretion?
1) prostaglandins (E2 & I2)
2) also cytoprotective via bicarbonate and mucus release - from superficial epithelial cells