B3-072 Viral Infection-HIV Flashcards
HIV drug resistance testing is recommended at
diagnosis
[genotypic or phenotypic] testing is preferred
genotypic
Should ART initiation be delayed while awaiting resistance results?
No, modify later
standard genotypic drug resistance testing tests for mutations in
RT and PR
if integrase mutation is a concern, providers must ensure this is also tested (AIII)
RAPID START ART
bictergravir/tenofovir/emtricitabine
or
dolutegravir (or boosted darunavir) + tenofovir + emtricitabine (or lamivudine)
ART only for individuals who are HLA-B5701 negative and without HBV coinfection
dolutegravir/abacavir/lamivudine
illness script: weight loss, immunodeficiency,cough, hypoxic respiratory failure, bilateral plumonary infiltrates, HIV
PJP
when should PJP prophylaxis be administered?
CD4 <200
when should toxoplasma gondii prophylaxis be administered?
CD4 <100 cells
when should M. avium prophylaxis be administered?
CD4 <50 cells
PJP is diagnosed using a _______ on a sputum sample
silver stain
therapy for PJP
trimethoprim-sulfamethaxozole
abacavir hypersensitivity causes
rash on face and chest