B11-hormonal control Flashcards
What does the hormonal system do
are chemical messengers from glands
they generate a response by regulation by homeostasis and other processes
-their effect is they travel to the target organ in the bloodstream and bind to receptors on the surface of organs (slower than nervous system! But longer lasting)
-e.g. insulin, ADH, adrenaline, thyroxin, cortisol, testosterone, oestrogen
What are hormones
They are chemical messengers from the glands
What are target hormones
Where the hormones produce an effect and have receptors on the cell membrane that pick up the hormone molecules triggering a response in the cell
What is type 1 diabetes
It is when your pancreas doesn’t make enough or any insulin your blood glucose concentration is not controlled. Which caused various problems when eating and with weight and tiredness.
What causes type 1 diabetes
There seems to be a genetic element to development of the disease usually starting in young children and teenagers.
Treatment of type 1 diabetes
You have to inject insulin as replacement insulin before meals every day and it is successful but it does not cure it and there is no cure yet. Also you need to be careful about the levels of carbohydrates you eat, regular meals and exercise but it needs to be carefully planned to keep your blood glucose levels steady. There are possible cures for type 1 diabetes from pancreatic transplants and maybe embryonic stem cells
What is type 2 diabetes
The pancreas still makes insulin but it may make less than your body needs and your body cells stop responding properly to the insulin made.
What causes type 2 diabetes
A very common diabetese and gets more common as you get older and is often linked to obesity lack of exercise or both and there is a strong genetic tendency to develop it.
Treatment of type 2 diabetes
No need for injections and many people can restore their normal blood glucose balance by: eating a balanced diet with carefully controlled amounts of carbohydrates, losing weight and doing regular exercise. If this doesn’t work there are drugs that help insulin work better on the body cells make more insulin in the pancreas and reduce the amount of glucose you absorb from your gut but if none of these work you probably need insulin injections.
The endocrine system gland:pituitary gland
Found in the brain -Controls growth in children - Stimulates the thyroid gland to make thyroxine (which controls rate of metabolism) - Stimulates ovaries to produce and release eggs in females - Stimulates testes to make sperm and testosterone in males
The endocrine system gland:adrenal
Located at the top of your kidneys secretes adrenaline which boosts the delivery of oxygen and glucose to your brain and muscles preparing for your body for flight or fight once danger over it stops, doesn’t involve negative feedback loop
Adrenaline causes
Your heart rate and breathing rate to increase
Stored glycogen in the liver to be converted to glucose for respiration
The pupils of your eyes to dilate to let in more light
Your mental awareness to increase
Blood to be diverted away from your digestive system to the bug muscles of the limbs
Endocrine system gland:ovaries(female)
Controls development of female secondary sexual characteristics and is involved in menstrual cycle also makes the female sex hormone oestrogen
Endocrine system gland:testes(male)
Controls the development of the male secondary sexual characteristics and is involved in the production of sperm
Endocrine system gland:pancreas
Controls the levels of glucose in the blood
Endocrine system gland:thyroid
In the neck uses iodine from diet to produce hormone throxide which controls the basal metabolic rate of the body(how quickly substances are broken down and built up, how much oxygen tissues use, how the brain of a growing child develops) plays an important role in growth and development buy in adults usually stays stable, this happens because of negative feedback vomteol involving pituitary gland and hormone it produces-thyroid stimulating hormone or TSH
Negative feedback system of throxine
If levels of thyroxine in the blood fall it’s detected by sensors in the brain so the amount of TSH released from the pituitary gland increases. TSH stimulates the production of thyroxine by the thyroid gland as the levels of thyroxine goes up it’s detected by the sensors and in turn the level of TSH released falls
If blood glucose levels rise from normal blood glucose level
Insulin is ‘secreted’ by the pancreas the effect of this is soluble glucose is converted into glycogen to be stored away in the liver it is also moved into the cells where it is used so blood glucose levels drop back to normal glucose level
If blood glucose levels drop from normal blood glucose level
Glucagon is ‘secreted’ by the pancreas the effect of this is the stored glycogen is converted back to glucose by making your liver break it down to the cells and bloodwhere it is used and amnio acids/fats are broken down so blood glucose levels rise back to normal blood glucose level
By using 2 hormones and the glycogen in your liver
Your pancreas keeps your blood glucose concentration fairly constant by using negative feedback control which involves switching between the 2 hormones
Autoimmune is
When the immune system attacks the pancreas
What is the negative feedback system
Works to maintain a steady state, if a factor in the internal environment increases changes take place to reduce it and restore the original level. And if a factor in the internal environment decreases changes take place to increase it and restore the original level. Whatever the initial change in negative feedback the response causes the opposite. Many hormones are involved in negative feedback systems like insulin and glucogen, most female sex hormones and thyroxine [LOOK AT DIAGRAM IN BOOK]
Day 1 of the menstrual cycle
Day 1 the lining breaks down and until day 7 oestrogen and progesterone as doesn’t move
Day 7 of menstrual cycle
The amount of progesterone released increases and the amount of oestrogen stays very similar until day 14 the lining is being built up at the moment but day 11 the amount of progesterone starts decreasing
Day 14 of the menstrual cycle
Egg is released and the lining is maintained as the oestrogen is back to normal levels by day 16 and the levels of progestrone start decreasing by day 22
Day 21 of the menstrual cycle
The egg has reached the uterus and the lining falls and it is ready for it to be fertilised
What is ovulation
When Every 28 days a mature egg is released